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Pathology Related To Spine 2022 - Feryanda
Pathology Related To Spine 2022 - Feryanda
Intake 13
2022
Leaning Outcomes
2 SO/JSPO/2022/Intake13
Contents
Type of Spinal Pathology 9) Spondylolisthesis
1) Fracture 10) Spondylolysis
1. Compression Fracture 11) Intervertebral Disc Herniation
2. Burst Fracture 12) Ankylosing Spondylitis
3. Tear Drop Fracture 13) Ossification of the Posterior
4. Jefferson Fracture Longitudinal Ligament (OPLL)
5. Hangman’s Fracture 14) Thoracic Outlet Syndrome
6. Facet joint Fracture 15) Low Back Pain
7. Seat belt (Chance) Fracture 16) TB spine
2) Atlanto-Occipital Dislocation (AOD) 17) Neurofibromatosis
3) C1/2 Dislocation 18) Charcot spine
4) Whiplash Injury 19) Paget’s disease
5) Spondylosis 20) Spine hematoma
6) Spinal osteoarthritis 21) Deformity
7) Spinal stenosis 1. Torticollis
8) Degenerative disc disease 2. Scheuermann’s Kyphosis
3. Scoliosis (*another chapter)
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Type of Spinal Pathology
Causes Regions
• Trauma • Cervical
• Non Trauma (Disease) • Thoracic
• Congenital • Lumber
• Unknown Idiopathic
Structures
• Bone
• Ligament
• Nerve
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[1] Fracture
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Fracture
• Causes for trauma
– Traffic accident
– Fall down
– Sports
– Violence
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Fracture
1. Anterior
2. Middle
3. Posterior
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Fracture
Posterior column :
• Ligamentum flavum
• Facet joint
• Interspinous ligaments
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Fracture
Middle column :
• Posterior aspect of
Intervertebral Disc
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Fracture
Anterior column :
• Anterior aspect of
Intervertebral Disc
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Fracture SUPER IMPORTANT
• Major Injuries
• Compression
• Burst
• Fracture – Dislocation
• Seat belt type
• Minor Injuries
• Transverse processes
• Spinous processes
• Articular process
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Compression Fracture (1)
Overview
• Vertebra breaks and collapses
• Failure of anterior column
• The middle column is intact as a hinge
• Can put pressure on the spinal cord and nerves by compression
itself or protrusion of bone into spinal canal in the worst cases
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Compression Fracture
Causes
• Trauma
– A fall, a forceful jump, a car accident,
etc.
– Downward pressure when spine
bending position
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Compression Fracture
Osteoporosis
• Bone is getting weaker
• Bones become brittle and fragile
from loss of tissue, typically as a
result of hormonal changes, or
deficiency of calcium or vitamin
D
• Common in old generation
people (usually old women)
• Tend easy to fracture, and tend
to get compression fracture
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Compression Fracture
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Compression Fracture
Causes by
Osteoporosis
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Compression Fracture
Symptom
• Traumatic accident
– Severe pain at back
• Osteoporosis
– No symptom at first
– Back pain start slowly and get worse with walking
• Common at T12-L2
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Compression Fracture
Treatment
• Traumatic accident
– Stable → Conservative treatment
– Unstable → Surgical treatment
• Osteoporosis
– Conservative treatment would be a
first choice
– BKB (balloon Kyphoplasty)
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Compression Fracture
Orthotic Treatment
• Orthotic Goal?
• Biomechanical principle?
• Conservative treatment? Or surgical treatment?
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Burst Fracture (2)
Overview
• More severe than
compression fracture
• Occur from;
– Compression force
– Flexion force
– Extension force
– Rotation force
• Failure of anterior column
and middle column
• Most common junction T/L
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Burst Fracture
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22 Intake13
Tear Drop Fracture (3)
• Flexion Teardrop
– Extreme flexion and
axial loading at cervical
– Most severe – dive into
pool
– Vertebral column shift
posteriorly
Risk of SCI
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C1 Fracture “Jefferson fracture” (4)
• is a bone fracture of the
anterior and posterior
arches of the vertebra
• commonly results from
axial load to the head
combined with
hyperextension of the
cervical part
• commonly results from
diving into shallow
water
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C1 Fracture “Jefferson Fracture”
1. Burst Fracture
• Most common
• Compression (axial load force)
2. Posterior arch Fracture
3. Lateral mass fracture
4. Anterior arch fracture
5. Transverse Process fracture
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C1 Fracture
“Jefferson fracture”
Video:
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https://www.youtube.com/watch?v=XyLW
Hangman Fracture (5)
Fracture
caused by
extension and
compression
at C2
Fracture at
pars
interarticularis
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There are type I, II, IIa and type III
• Stable
• Unstable
Video: https://www.youtube.com/watch?v=BuonvKW7Uxo
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Facet Joint Fracture (6)
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Unilateral Facet Joint Fracture
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Bilateral Facet Joint Fracture
Radiographic features:
(best seen on lateral view)
1. Complete anterior dislocation of
affected vetebral body by half or
more of the vertebral body AP
diameter.
2. Disruption of the posterior
ligament complex and the anterior
longitudinal ligament
Unstable
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(7)
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Seat belt Injury or Chance Fracture
Anterior
Longitudinal
Ligament
Annulus Fibrous
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Flexion distraction or Seat Belt type Injury or
Chance fracture
Alar Ligament
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[2] Atlanto-Occipital dislocation (AOD)
Hyperextension distraction
and rotation of cranio-
cervical junction
Causing disruption of
carnio-cervical ligament:
Alar ligament
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Atlanto-Occipital dislocation (AOD) - Type
Type 2 Distraction
Type 3 Head displaced posteriorly
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[3] C1-C2 Dislocation
Atlanto-Axial Dislocation and
Fracture
Causes :
- Direct Trauma (Flexion
extension injury Traction or
rotation
- Bone Disorders
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[3] C1-C2 Dislocation
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[4] Whiplash Injury
• Non-medical term describing a range of injuries to the neck caused
by or related to a sudden distortion of the neck associated with
extension, although the exact injury mechanism(s) remain unknown.
• Usually it occurs in cases of car accident.
• No always visible on x-ray or scan
• Cervical pain, ringing in the ear, and dizziness.
• Stretching of ligaments. Rupture of ligaments
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General Symptoms of Whiplash
• Neck pain and stiffness
• Worsening of pain with neck movement
• Loss of range of motion in the neck
• Headaches, most often starting at the base of the
skull
• Tenderness or pain in shoulder, upper back or
arms
• Tingling or numbness in the arms
• Fatigue
• Dizziness
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[5] Spondylosis
• Spondylosis refers to degeneration (progressive diseases)
of the spine
• It is not a pathology but a term to describe pain caused
from degenerative conditions of the spine
• Pathologies
– Spinal osteoarthritis
– Spinal stenosis
– Degenerative Disc Disease
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[6] Spinal Osteoarthritis
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[7] Spinal Stenosis
• Narrowing of the spinal canal
⇨ Compression of the spinal cord or spinal nerve
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[7] Spinal Stenosis
Causes
• Degeneration in the spine
• Anatomical debris that has been created by the natural aging process
– Spinal osteoarthritis
– Degenerative disc disease
– Spondylolisthesis
– Calcification of the ligamentum flavum
– Bone spur
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[7] Spinal Stenosis
(Foraminal Stenosis)
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[7] Spinal Stenosis
Foraminal stenosis
• Compression of spinal nerve root when passing through
neural foramen
• Caused by bone spur, DDD
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[7] Spinal Stenosis
Symptoms (Lumbar)
• Back pain
• Sciatica (due to irritation or compression of
sciatic nerve)
– Pain at buttock, thigh and leg
– Numbness and tingling at buttock and legs
– Muscle Weakness
• Bowel and bladder dysfunction
• Intermittent claudication
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[7] Spinal Stenosis
Symptoms (Lumbar)
Symptoms (Cervical)
• Myelopathy
– Compression of spinal cord
– Loss of function in upper and
lower extremities
– Bowel and bladder dysfunction
– Spasticity
• Radiculopathy
– Compression of nerve root
– Pinched nerve
– Pain at shoulder
– Muscle weakness, numbness,
tingling
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[7] Spinal Stenosis
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[8] Degenerative Disc Disease
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[9] Spondylolisthesis
Overview
• Vertebra slips anteriorly
• May lead to your spinal cord or nerve roots being squeezed
(spinal stenosis)
• Common at L4/5 or L5/S1
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[9] Spondylolisthesis
Causes
• Can be caused by facet joint fracture (spondylolysis)
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[9] Spondylolisthesis
Causes
• Repetitive stress to the spine
– Stress fracture by sports (teens)
• Degenerative factor
– The joint of the vertebrae becoming worn and
arthritic
– DDD, osteoporosis, muscle weakness (older
adults)
• Trauma
• Congenital
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[9] Spondylolisthesis
Symptoms
• Back or buttock pain
• Pain that runs from lower back to down (one or both legs)
• Numbness or weakness in one or both legs
• Difficult to walk (intermittent claudication)
• Leg, back or buttock pain that gets worse when bend backward
or twist
• Loss of bladder or bowel control (in rare case)
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[10] Spondylolysis
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[10] Spondylolysis
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QUICK REVIEW…..
• Spondylosis
• Spondylolysis
• Spondylolisthesis
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[11] Intervertebral Disc Herniation
• Known as Spinal disc herniation, slipped disc, herniated disc…
• Nucleus pulposus comes out to posterior or side
• Common at L4/5, L5/S1, and C5/6 (C4/5, C3/4)
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[11] Intervertebral Disc Herniation
Causes
• Disc degeneration
– Gradual, aging-related wear and tear
• Risk factor
– Weight
• Excess body weight causes extra
stress on the disc
– Occupation
• Repetitive lifting, pushing, bending
sideways and twisting
• Driver
– Bad posture
– Smoking
– Genetics
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[11] Intervertebral Disc Herniation
Symptoms (Lumbar) Symptoms (Cervical)
• Back pain • Neck pain
• Pain at buttock, thigh and leg • Pain at shoulder and arm
• Numbness and tingling • Numbness and tingling
• Muscle Weakness • Muscle Weakness
• Bowel and bladder dysfunction • Bowel and bladder dysfunction
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[11] Intervertebral Disc Herniation
Symptoms (Radiculopathy) Symptoms (Myelopathy,
• Pain Cauda equina syndrome)
• Numbness and tingling • Dysfunction of motion
• Muscle Weakness – Difficult to walk, run, write, eat
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[11] Intervertebral Disc Herniation
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[11] Intervertebral Disc Herniation
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Spinal Stenosis vs Intervertebral Disc Herniation (1)
Spinal stenosis Intervertebral disc herniation
MRI diagnosis
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Spinal stenosis vs Intervertebral Disc Herniation (2)
Intermittent
+ -
claudication
SLR - +
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[12] Ankylosing Spondylitis
• Chronic Spinal Inflammation
• Unknown cause – genetic?
– Common in men, 10-30 years old
• Causes pain & stiffness
• Can lead to fusion (bamboo spine)
– Loss of mobility
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[12] Ankylosing Spondylitis
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[12] Ankylosing Spondylitis -
Treatment
• There's no cure for ankylosing spondylitis (AS),
but treatment is available to help relieve the
symptoms.
• Treatment can also help delay or prevent the
process of the spine joining up (fusing) and
stiffening.
– exercise
– physiotherapy
– medication
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[13] Ossification of the Posterior Longitudinal Ligament
(OPLL)
• Abnormal calcification of
the posterior longitudinal
ligament
• Unknown cause – genetic?
– Common in men, elderly,
Asian
• Cervical region
• Myelopathy
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[14] Thoracic Outlet Syndrome
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[14] Thoracic Outlet Syndrome
• Common in young women who has sloping
shoulder, or the person who work with upper
limb such as hairstylist, PC worker
• Test
– Morley
– Adson
– Wright
– Roos
– Eden
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[14] Thoracic Outlet Syndrome
• Orthotic treatment
– Lift up clavicle and
scapula
– Positioning (reduce
kyphosis)
– Open thoracic outlet
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[15] Low Back Pain
• Mechanical Low Back Pain
• Non specific pathology
• Not found obvious cause
– No any changes on X-ray
– No sciatica
• Either acute or chronic
– Muscle weakness
– Skeletal instability
– Acute Injury
• Common in men who are hard
workers, heavy weight, Driver or office
worker
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[15] Low Back Pain
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[15] Low Back Pain
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[15] Low Back Pain
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[16] Tuberculosis Spine (TB Spine)
• M.tuberculosis infection (primarily in lungs)
• Include: pulmonary, genitourinary, skeletal, pericardium,
meninges
• Skeletal TBPott’s disease (affects spine mostly but also
knee and hip)
• Synonim: tuberculosis spondylitis
• Symptoms
Fever and weight loss
Localized pain
Paravertebral abscess
Neurological impact, eg: paraplegia
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[16] TB Spine/ Pott’s Spine
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[16] TB Spine / Pott’s Spine
Pathogenesis
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[16] TB Spine / Pott’s Spine
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[16] TB Spine / Pott’s Spine
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[16] TB Spine / Pott’s Spine
Clinical Features
Active Stage
1. Constitutional symptoms 4. Deformity: Knuckle (1 or 2
• Malaise vertebrae) ; Gibbus (2 or 3
vertebrae) ; Kyphus
• Loss of weight/appetite (angular kyphosis > 3
• Night sweats vertebrae)
• Evening rise of 5. Cold abscess may be
temperature present
2. Back pain 6. Paraplegia (if neglected in
3. Spine stiffness: spasm of early stages)
para-vertebral muscle **Several of these signs and
symptoms may be absent
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TB Spine
Healed Stage Healing is indicated by
Patient neither looks ill nor feel
ill Decreased soft tissue
shadow
No systemic features but the Return of normal
deformity that occurred density
during active stage, Bony ankylosis
however: persists.
Erythrocyte sedimentation
rate (ESR) falls
There is radiological
evidence of bone healing in
serial x-rays.
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TB Spine
Radiological Investigations
TYPE
1. Paradiscal Lesions
• Most common
• Narrowing of the disc
• Destruction of subchondral bone with
subsequent herniation of the disc
into the vertebral body
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TB Spine
TYPE
2. Anterior Lesions
• More common in thoracic spine in children
• Both pressure and ischemia combine to produce anterior
scalloping
• Collapse of the vertebral body and diminution of the disc
space is usually minimal and occurs late
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TB Spine
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Posterior view
TB Spine of the pelvis
TYPE
3. Central Lesions
• Centered on the vertebral body
• Disc not involved
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TB Spine
TYPE
4. Appendicial Lesions
• Uncommon (<5%)
• Radiographically- erosive
lesions, paravertebral shadows
with intact disc space
• Rarely, present as synovitis of
facet joints
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TB Spine
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TB Spine
Complications:
• Paraplegia • Secondary infection
• Cold abscess • Amyloid disease
• Spinal deformity • Fatality
• Sinuses
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TB Spine
Staging of neurological deficit
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TB Spine
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[17] Spine Neurofibromatosis
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Spine Neurofibromatosis
Skeletal associations
Generalized: Focal:
• Osteoporosis • Spinal deformity
• Osteomalacia • Long bone and sphenoid wing dysplasia
• Chest wall and dental abnormalities
• Short stature
• Cystic osseous lesions
• Macrocephaly
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Spine Neurofibromatosis
Neurofibromatosis type 1 (NF1)
• Von Recklinghausen disease
• Mostly affects nerves of the outer parts of the body
(peripheral nervous system)
• Common sign: café-au-lait spots (>6)
• Lisch nodules in eyes
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Spine Neurofibromatosis
Neurofibromatosis type 1
Skeletal features
• Kyphoscoliosis
• Posterior vertebral scalloping
• Posterior hypoplastic elements
• Enlarged neural foramina
• Ribbon rib deformity, rib notching, dysplasia
• Dural ectasia
• Tibial pseudoarthrosis
• Severe bowing
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Spine Neurofibromatosis
Neurofibromatosis type 1
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Spine Neurofibromatosis
Neurofibromatosis type 1
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Spine Neurofibromatosis
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[18] Charcot Spine
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Charcot Spine
Etiology
• SCI
• Diabetes mellitus neuropathy
• Multiple sclerosis
• Syringomelia
• Leprosy
• Etc
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Charcot Spine
Degenerative Cascade
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Charcot Spine
Symptoms
• Localized low back pain
• Loss or increase of spasticity
• Audible noise with motion of the spine
• Kyphosis or scoliosis
• Autonomic dysreflexia
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[19] Paget’s Disease
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Paget’s Disease
Symptoms:
• Bone pain (the most common symptom)
• Secondary osteoarthritis (when Paget disease occurs around a
joint)
• Bony deformity (most commonly bowing of an extremity)
• Excessive warmth (due to hypervascularity)
• Neurologic complications (caused by the compression of neural
tissues)
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Paget’s Disease
Phases
• Lytic
Increase of bone turnover rate
• Mixed (lytic and blastic)
Rapid increase in bone
formation
• Sclerotic
Bone formation dominates
(woven bone)
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Paget’s Disease
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Paget’s Disease
Clinical features
• Localised pain and tenderness
• Local temp ↑ hypervascularity
• Bone size ↑ (changing hat size)
• Bowing deformities
• Kyphosis
• Decreased ROM
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Paget’s Disease
Complications
• Optic and auditory nerve compression
• Heart failure
• Malignancies (eg: osteosarcoma)
• Deformity and fractures (eg: paraplegia, quadriplegia)
• hyperparatyroidism
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[20] Spinal Hematoma
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Spinal Hematoma
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Spinal Hematoma
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Spinal Hematoma
Association with:
• Vascular malformation
• Coagulopathies
(eg: congenital hemophilia)
• Myelitis/vasculitis
(eg: tumor)
• Symptoms
– Sudden onset of severe back pain, or radicular pain,
depending on the location of the bleeding
– Pain may be exacerbated by percussion of the spine or by
movements that increase intraspinal pressure (coughing or
sneezing)
– Neurological symptoms may not develop until hours to days
after the onset of back pain, difficult for early diagnosis to
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Spinal Hematoma
• Signs
– There may be tenderness to palpation of the spine
– Motor and sensory deficits depend on the level and size of the
hematoma
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Spinal Hematoma
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[21] Spine Deformities
TORTICOLLIS
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Torticollis
• Latin word = Twisted neck
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Congenital Muscular Torticollis
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Congenital Muscular Torticollis
• Clinical Presentations
– Spasm of the sternocleidomastoid muscle on the
same tilt
– Head tilt toward the tightened muscle and chin
rotation to the opposite site
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SCHEUERMANN’S KYPHOSIS
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Alignment of Spine
• Normal thoracic
kyphosis 20 - 40°
• Normal lumbar
lordosis 55 - 65°
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Scheuermann’s Kyphosis
• It is a rigid thoracic
hyperkyphosis by >45°
• Unknown cause
• There are 2 forms:
– Thoracic SK most
common form
– Thoracolumbar/Lumbar
SK
• Associated with
increased back pain
• No vertebral wedging
involved
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Thoracic Scheuermann’s Kyphosis
• 12 – 15 years old , M > F
• Thoracic deformity with compensatory cervical lordosis
• The forward bending test to check the excessive of
kyphosis
• 30% associated with mild scoliosis
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Scheuermann’s Kyphosis
• Radiographs
– Excessive khyposis
– Vetebral wedging >5°
on 3 vertebrae
– End plates irregularity
– Narrowing of disc
space - anteriorly
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Scheuermann’s Kyphosis
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Thank you
Questions?