BUG BUSTERS

TOPICAL PREPARATIONS INTRAVITREAL PREPARATIONS

ANTIBIOTICS
Shelf Repeat
Name Vial Size Brands Strength Preparation Refrigeration Shelf Life Spectrum Name Strength Brand Vial Size Preparation Refrigeration
Life
Spectrum
Injection
1 Vancomycin 500mg Ancomycin 50mg/ml "Reconstitute 500 mg 4 degrees 1week at Active against 1 Vancomycin 1 mg/ Ancomycin 500mg Reconstitute 500mg of 4 degrees C 24 hrs Active against 72hrs
Celovan (5%) of vancomycin powder 4 degree GPCs - 0.1 ml Celovan vancomycin powder for GPCs -
Covancin for injection with 2 MRSA, MDR Covancin injection with 10 ml sterile MRSA, MDR
ml sterile water/BSS. Staphylococcus water/BSS. Take 0.2 ml Staphylococcus
Add to epidermidis of this solution and make epidermidis
8ml of artificial tears" it 1 ml.
2 Cefazolin 2.25mg/ 0.1 Azolin 500mg Reconstitute parenteral 4 degrees C 24 hrs GPC, GPB, 24hrs
2 Cefazolin 500mg Azolin 50mg/ml "Reconstitute 4 degrees C 1week at GPC, GPB, ml Cefadin Cefazolin 500mg with 2ml E.coli, Proteus,
Cefadin (5%) parenteral Cefazolin 4 degree E.coli, Proteus, Cefacas sterile water. Take 0.1 ml H.influenza
Cefacas 500mg with 2ml sterile H.influenza of this solution and make
water available with it 1 ml.
the injection
3 Amikacin 0.4mg/ 0.1ml Abm , Acil 100mg/ From Parenteral Amikacin 4 degrees C 24 hrs Gram neg esp 24-
and add to 8ml of
, Acmacin 2ml 100mg/2ml or 50mg /1 ml Pseudomonas, 48hrs
artificial tears"
500mg/ take 0.2 ml and add 2.3 ml Mycobacterium
3 Tobramycin 80mg/ Alitop, 14mg/ml "Add 2ml/80mg of 4 degrees 1week at Aerobic 2ml sterile water. & Nocardia
2ml Bactob (1.4%) parenteral tobramycin 4 degree Gram-negative From Parenteral Amikacin
to commercially organisms 500mg/2ml take 0.2 ml and
available tobramycin add 6.15 ml sterile water.
eye drops
4 Gentamycin 0.2 mg/ 0.1 ml Biogracin 80mg/ 2ml Take 0.1 ml solution from 4 degrees C 24 hrs Aerobic GNBs 72-
0.3% 5 ml 15mg/5ml)"
Garamax 2ml/80mg of parenteral 96hrs
4 Gentamicin 80mg/ Biogracin, 14mg/ml "Add 2ml/80mg of 4 degrees 1week at Aerobic GNBs gentamicin and add 1.9 ml
2ml Garamax (1.4%) parenteral gentamicin 4 degree sterile water/BSS.
to commercial 5 Amphotericin 5µgm/ 0.1 ml Amfotex 50mg Add 10 ml of 5% dextrose 4 degrees C 24 hrs Yeasts, 48hrs
gentamicin ophthalmic B Ambilip to parenteral 50mg of filamentous
solution 0.3% 5 ml Amfitas amphotericin B powder. fungi (resistance
(15mg/5ml)" Take 0.1 ml of this solution reported for
5 Amikacin 250mg/ Abm, Acil, 2.50% Parenteral Amikacin Gram neg esp and add 0.9 ml of 5% various species
2ml Acmacin 250mg/2ml is mixed Pseudomonas, dextrose in the solution. ofAspergillus)
with 8 ml artificial Mycobacterium 6 Voriconazole 50-100µgm/ Voriva 200mg Mix 20 ml ringer lactate/ 4 degrees C 24 hrs Broad-spectrum 48hrs
tears & Nocardia 0.1 ml Voriz distilled water to 200 mg activity against
Voraze voriconazole lyophilized moulds and
6 Linezolid 200mg/ Anzolid, 2 mg/ml "Can use directly Aerobic GPC powder. Take 1 ml of the yeasts
100ml Linospan (0.2%) from parenteral including MRSA solution and add 9 ml of
Linezolid available as and VRE RL/distilled water to it. 0.05
200mg/100ml (2mg/ ml of the solution has 50-
ml) IV infusion" 100µgm/0.1 ml
7 Ceftazidime 500mg Afzid C-Zid 50mg/ml Reconstitute 500mg 4 deg C 1week at Aerobic GNBs, 7 Ceftazidime 2.25mg/ 0.1ml Afzid C-Zid 250mgml Take 0.1 ml solution from 4 degrees C 24 hrs Aerobic GNBs, 48-
(5%) of Ceftazidime powder 4 degree GPBs including 500mg/2ml 250mg/ml or 500mg/2ml of GPBs including 72hrs
for injection with 10 ml Pseudomonas parenteral ceftazidime and Pseudomonas
sterile water/BSS. add 0.9 ml sterile water/
BSS.
8 Imipinem 500mg Cilanem, 10mg/ml "To 500mg add 10ml 4 deg C 3 days at MDR GPB, 8 Ciprofloxacin 100µgm/ Alcipro 200mg/ "Directly loaded from the Room Temp "Broad-spectrum 12hrs
Cilaspene (1%) sterile water 4 degree GNBs including 0.1 ml sterile vial activity against
100ml
Take 1 ml of this Psedomonas, and injected intraviteally, aerobic Gram-
solution and add 4 ml therapeutic 0.05 ml" positive and
sterile water" option for Gram-negative
infections bacteria,
caused by MDR Actinomyces,
pathogens Nocardia spp."
9 Colistin 1million Xylistin 1.9mg/ml Reconstitute 4 deg C 1week at Gram negative
IU (0.19%) 1MIU(75mg) 4 degree bacilli and Multi 9 Moxifloxacin 200µgm/ Vigamox Topical Take 0.05 ml of 0.5% Room Temp "Broad-spectrum 12hrs
(75mg) Colistimethate drug resistant 0.1 ml 0.5% moxifloxacin(Preservative activity against
Sodium in 10ml sterile Pseudomonas & free) Gram-positive
water. Draw 1ml of Acinetobacter and Gram-
this and add 3 ml of negative
sterile water organisms"

ANTI FUNGAL
Name Vial Size Brands Strength Preparation Refrigeration Shelf Life Spectrum INTRASTROMAL PREPARATIONS
1 Amphotericin 50mg Amfotex 0.15% "Add 10 ml distilled or 4 degrees 1week at Yeasts,
B Ambilip sterile water to parenteral 4 degree filamentous
Amfitas 50mg of amphotericin fungi (resistance "From1% Topical solution voriconazole, take
B powder for injection. reported To be used Broad-spectrum activity
1 Voriconazole 50 µgm/ 0.1ml 1ml, add 19 ml ringer lactate to make 0.05mg/
Draw 3 ml of this and Aspergillus) immediately against moulds and yeasts
ml (50 µgm/0.1ml)"
add to 7ml of artificial
tears eye drops"
2 Voriconazole 200mg Voriva 1% Mix 20 ml ringer lactate 4deg C 1week at Broad-spectrum "Add 10 ml distilled or sterile water to
Voriz to 200 mg voriconazole 4 degree activity against parenteral 50mg of amphotericin B powder.
Voraze lyophilized powder moulds and Yeasts, filamentous fungi
From 5mg/ml solution take 0.2ml solution and
yeasts To be used (resistance reported
2 Amphotericin B 5 -10 µgm/ 0.1ml add 0.8ml BSS / sterile water. Now, take 0.1ml
immediately for various species
of this solution and add 0.9ml BSS/Sterile
ofAspergillus)
ANTI PROTOZOAL water to create 0.1mg/1ml Amphotericin B
1 Chlorhexidine 0.02% Add 5microlitre ofchlorhexidine Digluconate 4deg C 1week at Acanthamoeba equivalent to 10 µgm/0.1ml"
Digluconate solution (20% in water) in 5ml of Moisol 4 degree
using micropippete (1:1000 dilution)
2 Polyhexamethyl 0.02% Add 5microlitre of PHMB solution (20%) in 4deg C 1week at Acanthamoeba
Biguanide 5ml of Moisol using micropippete (1:1000 4 degree
(PHMB) dilution)
INTRAVENOUS
SUBCONJUNCTIVAL DOSE S.No

1
Drug

Vancomycin 2 g daily in 2 doses

Dose

Covancin, Cp-Van
Brands

S.No Drug Dose (mg)

2 Cefazolin 1–6 g daily in 3–4 divided doses Azolin, Cefadin, Ciprid
1 Vancomycin 25
3 Tobramycin 3–5 mg/kg daily in 2–3 doses Tobacin, Tobax
2 Cefazolin 100
4 Gentamicin 3–5 mg/kg/ day in 2–3 divided doses Alpagen, Avrocin
3 Tobramycin 10–20
5 Amikacin 15 mg/kg/day in 2–3 divided doses Abcin, Abiox
4 Gentamicin 10–20
6 Ceftazidime 2–6 g daily in 2–3 divided doses Fortum, Megazid
5 Amikacin 25
7 Imipinem 2 g daily in 3-4 divided doses Cilanem, Cilaspene, Lastinem
6 Ceftazidime 100–200
6 mg/kg IV every 12 hours (24 hours), then 4mg/kg × 12 hours
8 Voriconazole Voriva, Voriz
9 Voriconazole 10 (Not used) or 200 mg/day BD
10 Amphotericin B 5–10 9 Amphotericin B 10–20 µgm/ml infusion Amfitas, Amfocare