HIDDEN CRISIS LABORATORY HOW 150 PEOPLE DIE EVERY YEAR FROM FUNGAL INFECTIONS : VAiLETIEORITTUBS AE fi COLLECTION UNITS UNITS ai 1B,Gulshane Shamim Comm, Yaseenabad, EB Area i : : 48/39, Block 3-0, Opp. Abbasi, Shaheed Hospital, Nazimabad : ¥ 4 18-68, Sector, 81, Near Qatar Hospital, Orangi Town 7 ‘ ‘Ground Floor, Plot No. 58-C, Badar Comm., St. 12, Ph. V-Ext,, DHA > |, Makhdoom Blessing, sc5, Block N North Nazimabad a \ 4-Ground Floor, Fatima Heights, Doctor Lane, Saddar, Cantt. SEECIALISLLAG IN Rene naa t www.onehealth.pkSerious Fungal Infections. HIV/AIDS. 2016 > 15M ot on treatment TUBERCULOSIS AND TB-LIKE FUNGAL DISEASES 5,200,000 Ea CANCER Stan, INFECTIONS rn oa, son > EYE INFECTIONS (FUNGAL KERATITIS) inion oer wer > a NEGLECTED TROPICAL FUNGAL DISEASES The size of the problem Aspergillosis 56K Histoplasmosis 80x Cryptococcal meningitis 181 Peumooystis preumona (PCP) 250% e <@ @--« 42M ‘AIDS deaths a yoar ore oth ACS Per reo cern} Vital recover Naan ope Pere poetWhy the accurate diagnosis of Fungal Infection is important? 3.2 million Pakistanis living with serious infections includ- ing keratitis, which can cause blindness, and the life-threat- ening Candida auris infection. Laboratory diagnosis of Fungal infections remains challenging and virtually forgot- ten area in Pakistan and lack of routine diagnostic testing for fungal diseases exacerbates the problem of antimicrobial drug empiricism, both antibiotic and antifungal - thanks to recent advancement in Fungal Diagnostic capabilities that allowed an increasing number of Fungal infections to be ac- curately diagnosed and treated with appropriate Antifungal drugs and support stewardship programs and control AMR. 1-Fungal Smear/ Microscopy Fungal infection is caused by fungi or microorganisms like yeast or mold, If the fungal infection is superficial, then a simple Microscopic examination is helpful to identify the infection causing organism, and the root cause of the fungal infection. Reporting: 6-8 Hours Peet Most fungal infections occur on the skin, mouth, or genitals. Some infections can be more serious and occur inside the body, such as inthe lungs or the blood. The most direct and Per tena age Seep) Or Tea reer nn ae ET Cue) Me eg en eae ee ‘number of immunosuppressed individuals has increased. A fungal culture can aid in identifying the type of fungus pres- ent so that the best treatment choice can be made. ST ACE LL Smee Mere Bot) BOs oe ao) + Body fluids (All) Ber Teer) ed ecu) Be eR See eae eacrey Se Ee) Bren nan) + Nasal (Tissue & Secretion) SO eee a) BE era) SSS n LD) cee cer) Be) BCE arg Boy BriersSen ise Ct eC Ce Re py laboratorians to healthcare professionals and the general Cae suc a se} Ge De UCU We mea ar UC Pee uuu Ns ee es LMR and report MIC of following Antifungal Drugs: Beary l St earr + Flucytosine a at erty Bae Barco 24-48 hours Fresh and Pure Culture in Sealed plate or agar stant in individually sealed bag, Parry Ley ree Ree A notte sk Rt Leg cad cus species complex (Cryptococcus neoformans and Crypto Roce PAR a Ti eee CES ena Reuse] aon at aoe cau Eo ciated with this disease. Blood, Serum, Plasma & CSF 5-Aspergillus Galactomannan Aspergillus spp. are filamentous fungi found worldwide and ‘an live both indoors and outdoors. Invasive aspergillosis (/A) is caused by breathing in these fungal spores. [Ais one of the most significant threats to recipient of hematopoietic stem cell, solid organ transplants and individuals with suppressed immune systems. There has been a significant rise in the inc dence of IA in the last two decades due to the widespread Use of treatments, such as chemotherapy and immunosup- pressive agents. Hence, an early diagnosis and initiation of therapy strongly influence outcome. Specimen: Serum & BAL Reporting: 6-24 Hours 6-Glucan Detection Most pathogenic fungi have 1,3-B-D-Glucan in their cell walls and minute, but detectable quantities are released into the circulation during infection. Detection of elevated levels of 1,3:8-D-Glucan is useful for the early diagnosis of fungal fections and to support decisions to withhold or withdraw antifungals. Hence, there is significant utility 1,3--D-Glucan test in patients at risk such as; ICU/MICU/NICU, Mechanical Ventilation, Stem Cell and Organ Transplants, HIV, Cancer Treatment, Diabetes, Central Venous Catheters, Hemodialy- , Gastrointestinal Surgery and Total Parenteral Nutri Specimen: BAL & Serum Reporting: Wednesday/ SaturdayHIDDEN CRISIS LABORATORY HOW 150 PEOPLE DIE EVERY YEAR FROM FUNGAL INFECTIONS : VAiLETIEORITTUBS AE fi COLLECTION UNITS UNITS ai 1B,Gulshane Shamim Comm, Yaseenabad, EB Area i : : 48/39, Block 3-0, Opp. Abbasi, Shaheed Hospital, Nazimabad : ¥ 4 18-68, Sector, 81, Near Qatar Hospital, Orangi Town 7 ‘ ‘Ground Floor, Plot No. 58-C, Badar Comm., St. 12, Ph. V-Ext,, DHA > |, Makhdoom Blessing, sc5, Block N North Nazimabad a \ 4-Ground Floor, Fatima Heights, Doctor Lane, Saddar, Cantt. SEECIALISLLAG IN Rene naa t www.onehealth.pk