compromise nutritional status. This paper based its research on nutritional biomarkers in drug addicts who had not had nutritional counseling or treatment. The methodology was analytical, observational and based on a convenience sample. the nutritional markers that were studied in the blood were ASL, ALT, glucose, urea, creatinine, total cholesterol, HDL cholesterol, triglycerides and hemoglobin of 103 individuals who had already been diagnosed with some behavior or mental disorder due to drug abuse and other psychoactive substances. The type of drugs used were alcohol, cocaine, amphetamines, MDNA, opioids, marijuana and in the results they found that the mean of hemogloin, total cholesterol, HDL and creatinine was statistically different in gender and age.