NAME OF DRUG ROUTE, MECHANISM INDICATIONS INDICATIONS SIDE NURSING

DOSAGE OF ACTION EFFECTS RESPONSIBILITY

AND
FREQUENCY
GENERIC NAME: 750 mg (IV Binds to • Treatment of •Hypersensitivity GI: • Check for the
CEFUROXIME bolus) in 10 cc bacterial cell certain infections to cephalosporin diarrhea, doctor’s order.
sterile water membranes, caused by bacteria or penicillin nausea, • Observed 10 rights
BRAND NAME: every 8 hours inhibits cell wall including • Carnitine antibiotic of drug administration
Zinacef after negative synthesis. pneumonia and deficiency associated • Check for history of
skin test It interferes with other lower colitis. allergies particularly
CLASSIFICATION: bacterial cell respiratory tract Skin: rash, Cephalosporin,
Therapeutic Class: wall synthesis by (lung) infection. pruritus, penicillin.
Anti-infective inhibiting the urticaria. • Check for
final step in the •To treat Urogenital: hypersensitivity by
Pharmacologic cross linking of respiratory Increased performing a skin test,
Class: peptidoglycan infection caused serum as ordered.
Second generation strands. by TB bacteria. creatinine • Administer
cephalosporins peptidoglycan and BUN, appropriate amount of
makes the cell decreased drug Cefuroxime
membrane rigid creatinine • Monitor daily pattern
and protective, clearance. of bowel activity, stool
without it Hemat: consistency.
bacterial cell Hemolytic • Monitor I&O, renal
ruptures and die. anemia function tests for
(Jones and MICS: nephrotoxicity.
Barrtlett, 2018) Anaphylaxis • Be alert for super
infection: fever,
vomiting, diarrhea,
and anal/genital
pruritus, oral mucosal
changes.
 •Document drug’s
name, time and date of
administration.
• Educate client for the
possible adverse
reactions of the drug.

Saunders, (2019). Nursing drug handbook. ELSEIVER.