An Interesting TOPIC

for Minor Thesis

Ronny Lesmana
 The scope of medical writing
Internal reports

Regulatory reports

Conference presentations
• abstract
• oral presentation
• poster

Journal articles
• original research paper
• review article
• case report
• letter to editor
“VERY VERY IMPORTANT”
IDEA AND NOVELTY
Follow the right road
 Scientific Reports
"In science, the credit goes to the man who
convinces the world, not to the man to whom
the idea first occurs."
--Sir William Osler

"Writing is an art. But when it is writing to

inform, it comes close to being a science as
well."
--Robert Gunning, The Technique of Clear Writing
 Choose attractive research areas

• That are growing in interest

• Generate new ideas, vibrancy
• Have potential relevance
Stage 1: • Critical academic mass
Choosing your • Appreciated by close colleagues
topic
Where you have a relative advantage

– Match your interests, skills, experiences

– Potential collaborators
– Good resources for collecting and
analyzing data
 • Find a few very current articles—
typically with a web search or
accepted article section of a journal
Stage 2: • Research references from those
Research your articles
topic • Try to meet with relevant experts or
get in touch with them
• Find an issue that enables you to
create new insights
1. Discussion with peers based on Literature search
2. Discussion with peers based on interest issue
3. Discussion with peers based on problem in field
3. Discussion with peers based on problem in field
“VERY VERY IMPORTANT”
Materials QUALITY
RECHECK SOURCES
RECHECK SOURCES
Citation Management
 “FILTER AND RESEARCH”
SHARP JOURNAL INCLUSION
PRISMA DIAGRAM
 “DETAILS AND TABULATION”
SUMMARIZE JOURNALS IN TABLE
 Tabulate and review details articles

• It is a critical, constructive evaluation of literature in a

particular field through summary, classification, analysis,
and comparison. –MAKE TABLE

• If you write a scientific review, you have to use database

searches to portray the research. Your primary goal is to
SUMMARIZE everything and PRESENT a clear
understanding of the topic you’ve been working on.

• The analysis, evaluation, and comparison require use

theories, ideas, and research, relevant to the subject area
of the article.
 “RECHECK TOPIC”
FAIRLY JUDGE YOUR TOPIC
 IMPORTANT POINT:
choose topic experiment

topic

Graphic by Zhiyong Han, PhD

 Make your TENTATIVE
Summary/Frame of Thinking
 CONTOH :
Beberapa Publikasi bersama temen
Undergraduate FK
TB is still big issue in Indonesia
 ETHIONAMIDE is Correlated with Hypothyroidism

Ø Thionamide and PAS (para-aminosalicylate sodium) based MDR-TB regimens have been
associated with the development of primary hypothyroidism

Ø Mostly the reports of the hypothyroid case in MDR-TB treatment are originated from resource
poor countries, such as India and some African nations, where TB and human immunodeficiency
virus (HIV) are endemic and where other risk factors such as antiretroviral drug use, nutritional and
iodine deficiencies may also contribute to thyroid status.
Ø the incident reports are vary between 3.9% - 78%

Ø Ethionamide can lead to hypothyroidism by preventing the formation of thyroid hormone by

inhibiting the organification of iodine. Similar to methimazole, a drug that is used for treating
hyperthyroid.

Ø Ethionamide has similar structure with propylthiouracil (PTU) and methimazole which are
hyperthyroid medication, in which they are all come from thionamide group. This where the theory
of correlation between the use of ethionamide and the reversible hypothyroid in MDR-TB comes
from.
Alexandra M Dumitrescu and Samuel Refetoff, M.D. 2016
Thank You
For your
Attention