MECHANISM OF

DRUG NAME DRUG CLASS INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING RESPONSIBILITIES
ACTION
Generic Name: Analgesic Blocks pain impulses  Temporary  Contraindicated with  CNS: headache Before
Paracetamol (nonopioid) by reduction of allergy to  CV: chest pain,  Perform handwashing.
Antipyretic inhibiting synthesis of fever, acetaminophen. dyspnea, myocardial  Check doctor’s order.
prostaglandin. It  Mild to damage  Obtain patient’s health history.
Dosage: 300mg relieves fever by moderate pain Use cautiously for  Perform physical assessment
 GI: hepatic toxicity and
IVTT acting directly in the patients with: and obtain baseline data.
(specifically in failure, jaundice
hypothalamic heat-  Ensure right patient, right drug,
the client’s left  impaired hepatic  GU: acute renal failure, right dose, right time, and right
Frequency: PRN regulating center to leg pain function renal tubular necrosis route.
for pain cause vasodilation caused by  chronic alcoholism  Hematologic:  Assess skin color, texture,
and pathologic  pregnancy methemoglobinemia a- lesions; orientation, reflexes,
sweating, which helps fracture and  lactation cyanosis; hemolytic bowel sounds, BP, RR, and
dissipate heat. tissue anemia hematuria, renal function.
sarcoma) anuria; neutropenia,  Assess patient for any allergy,
leukopenia, past or present history of
pancytopenia, dependence to the drug.
thrombocytopenia,  Check the label of the drug
hypoglycemia upon getting the drug from its
storage, before preparing the
 Hypersensitivity: rash,
drug, and before administering
fever the drug.

During
 Identify patient.
 Explain procedure to the
patient, as well as the name of
the drug, its therapeutic and
side effects.
 Assess BP & RR periodically
during administration.

After
 Assess bowel function
routinely.
 Monitor patient for any adverse
reactions.
 Provide comfort measures.
 Document procedure
accordingly.
 MECHANISM OF
DRUG NAME DRUG CLASS INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING RESPONSIBILITIES
ACTION
Generic Name: Pharmacologic: Analgesic and anti-  management  Contraindicated with  CNS: headache Before
Celecoxib Specific COX-2 inflammatory activities of acute pain allergies to:  Dermatologic: rash,  Perform handwashing.
enzyme related to inhibition of (specifically in o sulphonamides, pruritus, sweating, dry  Check doctor’s order.
inhibitor the COX-2 enzyme, the client’s left mucous membranes,  Obtain patient’s health history.
o celecoxib,
Dosage: which is activated in leg pain stomatitis  Perform physical assessment
o NSAIDs or and obtain baseline data.
200mg/tab Therapeutic: inflammation to cause caused by  Hematologic:
Nonopioid the signs and o aspirin,  Ensure right patient, right drug,
pathologic neutropenia,
 significant renal right dose, right time, and right
Frequency: BID, analgesic symptoms associated fracture and eosinophilia,
impairment; route.
PRN for pain with inflammation; tissue leukopenia,  Assess skin color, texture,
does not affect the sarcoma)  perioperative pain pancytopenia, lesions; orientation, reflexes,
Route: PO COX-1 enzyme, which post CABG surgery; thrombocytopenia, bowel sounds, BP, RR, and
protects the lining of  bone marrow renal function.
the GI tract & has Use cautiously for depression,  Assess patient for any allergy,
blood clotting and patients with: menorrhagia past or present history of
renal functions  impaired hearing,  CV: chest pain, dependence to the drug.
 hepatic, and CV dyspnea, myocardial  Check the label of the drug
conditions damage upon getting the drug from its
 GI: hepatic toxicity and storage, before preparing the
drug, and before administering
failure, jaundice
the drug.
 GU: acute renal failure,
renal tubular necrosis During
 Hypersensitivity: rash,  Identify patient.
fever  Explain procedure to the
 Other: Peripheral patient, as well as the name of
edema, anaphylactoid the drug, its therapeutic and
reactions to side effects.
anaphylactic shock  Assess BP & RR periodically
during administration.

After
 Assess bowel function
routinely.
 Monitor patient for any adverse
reactions.
 Provide comfort measures.
 Document procedure
accordingly.
 MECHANISM OF
DRUG NAME DRUG CLASS INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING RESPONSIBILITIES
ACTION
Generic Name: Chemical class: Is structurally like  To manage  Hypersensitivity to  Musculoskeletal: Before
Gabapentin Cyclohexane- gamma-aminobutyric postherpetic gabapentin or its Arthralgia, arthritis,  Perform handwashing.
acetic acid acid (GABA), the main neuralgia components back pain, bone  Check doctor’s order.
derivative inhibitory  As adjunct to fractures, dysarthria,  Obtain patient’s health history.
Dosage: neurotransmitter in the treat partial joint stiffness or  Perform physical assessment
300mg/tab Therapeutic: brain. Although swelling, muscle and obtain baseline data.
seizures
Anticonvulsant gabapentin’s exact  To treat  Ensure right patient, right drug,
twitching, myalgia,
right dose, right time, and right
Frequency: OD mechanism of action restless legs positive Romberg test, route.
is unknown, GABA syndrome tendinitis  Assess skin color, texture,
Route: PO inhibits the rapid firing  CNS: Agitation, altered lesions; orientation, reflexes,
of neurons associated proprioception, bowel sounds, BP, RR, and
with seizures. amnesia, anxiety, renal function.
apathy, aphasia,  Assess patient for any allergy,
asthenia, ataxia, past or present history of
cerebellar dysfunction, dependence to the drug.
chills, CNS tumors,  Check the label of the drug
decreased or absent upon getting the drug from its
reflexes, delusions, storage, before preparing the
depersonalization, drug, and before administering
depression the drug.
 CV: Angina,
During
hypertension,
 Identify patient.
hypotension, murmur,  Explain procedure to the
palpitations, peripheral patient, as well as the name of
edema, peripheral the drug, its therapeutic and
vascular insufficiency, side effects.
tachycardia,  Administer medication with or
vasodilation without food and at least 2 hrs
 EENT: Abnormal vision, after antacid administration.
amblyopia,  Urge patient to take a missed
blepharospasm, dose as soon as he
cataracts, conjunctivitis, remembers. If the next dose is
in less than 2 hours, tell him to
diplopia, dry eyes and
wait 1 to 2 hours before taking it
mouth, earache, and then resume his regular
epistaxis, eye schedule. Caution against
hemorrhage, eye pain doubling the dose.
 Other: Angioedema,
dehydration, elevated
creatine kinase level, After
facial edema,  Monitor patient for any adverse
hyponatremia, reactions.
lymphadenopathy, viral  Monitor renal function test
infection, weight gain or results, and expect to adjust
dosage, if needed.
loss
 Monitor patient closely for
evidence of suicidal thinking or
behavior, especially when
therapy starts or dosage
changes.
 Provide comfort measures.
 Document procedure
accordingly.