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Life Sciences Real Estate
Life Sciences Real Estate
On a Booster Dose:
Life Sciences Real Estate
SP OT LI GH T
Savills Research
Contents Prologue
1. Prologue ........................................................................03 The global life sciences industry has been
on the rise, growing more rapidly than ever
2. Encapsulating the Findings......................................04 over the past decade. Its pace increased
significantly during the pandemic
3. Introduction...................................................................05 throughout 2020 and 2021 with demand
surging and access to capital continuing
4. India Life Sciences Sector: to expand.
Current State & Growth..............................................06 As the global community races to develop
new vaccines, ramp up production and
5. Life Sciences Enablers................................................07 distribution to combat coronavirus, India
is also strengthening its position in the life
Structural factors............................................................... 08 sciences industry. Currently, India is hailed
as the largest provider of generics globally
Rich demographic dividend - and is referred to as the pharmacy of the
world1.
India has a large skilled
While India’s growth continues in the
workforce............................................................................... 09
supply of generics, the country is swiftly
Cost efficiencies................................................................. 10 moving up the value chain and focusing
on innovation and R&D. Favourable
Growing number of government policies, large skilled
workforce, and cost efficiencies, among
institutional participants.............................................. 11 many other factors, are attracting venture
capital funding into the life sciences
6. Life Sciences Related Real segment. India is gaining momentum to
Estate Growth Potential.............................................12 develop a robust life sciences R&D hub that
will likely present a lucrative opportunity
7. Life Sciences Real Estate Specifications...............14 for private equity investors. As a testimony,
in July 2021, India witnessed its maiden
8. Life Sciences R&D Real Estate: investment by a global pension fund in life
Future Scenarios and Projection sciences R&D asset. A Canadian Pension
Fund along with Singapore-based wealth &
Model...............................................................................15 asset management firm jointly invested
USD 100 million (INR 7.5 billion) in life
9. Opportunity for Investors..........................................16 sciences R&D facilities in Genome Valley,
Hyderabad. This investment may prove to
10. Challenges.....................................................................18 be a stepping stone for more equity
investments into the segment.
11. Conclusion ....................................................................19
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of life sciences R&D real estate and
accelerated investments especially during
development phase. India needs to develop
a strategy that demonstrates its
resourcefulness and wherewithal as a
trustworthy partner to provide safe,
effective, and affordable platform for this.
Conservative Case
Realistic Case In this report, we have endeavoured to
estimate the growth of life sciences R&D
segment in India along with the potential
private equity institutional investment
opportunity. Since the development of life
sciences related real estate is driven by
economic growth and specifically, growth
of life sciences industry, we have developed
simulations based on a range of growth
152 27
Real Estate Demand (mn sq. ft.)
rate estimates. Going forward, we shall
closely observe this space for more
Private Equity Investment (USD bn) developments impacting related real
estate.
Optimistic Case
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On a Booster Dose: Life Sciences Real Estate On a Booster Dose: Life Sciences Real Estate
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On a Booster Dose: Life Sciences Real Estate On a Booster Dose: Life Sciences Real Estate
01 02 03
Financial Implication INR 3,000 crore INR 6,940 crore INR 15,000 crore
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Vietnam
15,800
country salary Key VC Funding Deals in Life Sciences in 2021, India
India
12,000 Malaysia Company Name Amount Raised (USD million)
Source Glassdoor, Savills Report “Science Cities, February 2021” 14,380 Ahmedabad
For more details on scientist salaries, please refer to Annexure II.
Axio Biosolutions
R&D Space Rents (USD/sq. ft./year) Hyderabad
61-113 20.9
UK SuVitas
22-105
USA At a rent of USD11-16/sq. ft. /year 17.5
for R&D space, India offers a
11-16 rental arbitrage of 82%-86%
INDIA compared to most other major Mumbai
Bengaluru
economies. Ampa Orthodontics
6-22 Private Ltd. HealthifyMe Wellness Onsurity
CHINA Private Limited Technologies
24.9
Source Savills India Research, Savills Report “Science Cities, February 2021” 28.9 18.8
Science cities are considered in this chart. UK – London, Cambridge, Oxford | USA – New York, Boston, San Francisco Bay Area, San Diego,
Seattle, Philadelphia, Research Triangle | India – Bengaluru, Chennai, Hyderabad, Mumbai, NCR, Pune | China – Shanghai, Beijing, Suzhou
Source Pitchbook
7. https://www.india-briefing.com/news/indias-pharmaceutical-industry-investment-trends-opportunities-incentives-18300.html/
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On a Booster Dose: Life Sciences Real Estate On a Booster Dose: Life Sciences Real Estate
• The Indian IT-BPM sector has • India’s domestic pharma market is valued
been the flag-bearer of India’s at USD 42 bn (INR 3 tn).
exports over the last 20 years.
• The domestic pharma market is expected
• Over the decade, the industry to grow 3X in the next decade as per the
grew by 102% reaching USD 191 Economic Survey 2021. It is likely to reach
bn (INR 14 tn) in revenues in FY USD 130 bn (INR 10 tn) by 2030.
2019-2020.
• India’s growth will continue in the supply of
• The industry added 1.8 mn generics, as the country aims to move up
employees, 70% higher over the value chain and also focus on
the last 10 years. innovation and R&D.
• Nature of work has evolved
from providing back-end
support to digital
transformation, R&D and
analytics.
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On a Booster Dose: Life Sciences Real Estate On a Booster Dose: Life Sciences Real Estate
Life sciences facilities and office space overlap to a certain extent; but,
Scenario Assumptions
there are distinct differences related to certain structural characteristics,
costs of development/ongoing capex, and tenant base. Realistic Case Optimistic Case
Assumption Rationale Assumption Rationale
Key Differences Between Life Sciences The average growth in the life The life sciences industry growth
Properties and Traditional Offices in India sciences industry in India has anticipated from global supply-
historically been around 10%-12%. chain rebalancing and favourable
The industry will continue to grow regulatory regime plays out faster
Structural: at a similar pace over the next 10 Scenario than as factored in the Realistic
years. case.
Life sciences lab spaces have certain
elements that differ from traditional
offices. These include higher floor load Assumption Metric* Assumption Metric*
capacity, higher floor-to-floor ceiling CAGR of Life Sciences Industry CAGR of Life Sciences Industry
heights, heavier HVAC usage, and Revenue over the next 10 years: Revenue over the next 10 years:
increased environmental control. 12% 16%
Additionally, life sciences properties
tend to be “low and wide” with larger
Conservative Case
floor plates.
Assumption Rationale
Assumption Metric*
The life sciences industry growth anticipated from
global supply-chain rebalancing and favourable CAGR of Life Sciences Industry Revenue over the
Costs: regulatory regime takes longer than as factored in next 10 years: 9%
Initial building infrastructure generally the Realistic case.
costs more in case of life sciences
Source : Savills India Research
properties than traditional offices, given *This is a subjective assumption, based on our discussion with industry experts.
the specific needs of lab tenants.
Per our estimates, in a Conservative Life Sciences R&D Real Estate Demand Potential in India
scenario, India has the potential to
Tenants: create a demand for approximately 72 from 2021 to 2030
Life sciences properties are typically million sq. ft. of life sciences research
and development real estate from 160 152
occupied by those involved in the
2021 till 2030. However, this may go
medical research industry: research 140
up to 152 million sq. ft. in an
institutions, pharmaceutical companies, Optimistic scenario. Realistically, 120
biotechnology firms, medical device this is estimated as 96 million sq. ft. 96
companies, and the like. Our estimate takes into 100
consideration the demand for life
80 72
sciences R&D real estate facilities as
Source : Savills India Research
well as R&D spaces in multi-tenanted
For more details on life sciences R&D asset specifications, 60
office buildings.
please refer to Annexure III.
40
20
0
Conservative case Realistic case Optimistic case
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On a Booster Dose: Life Sciences Real Estate On a Booster Dose: Life Sciences Real Estate
Per our estimates, life sciences research and development real estate
universe in India holds the potential to attract private equity
institutional investment amounting to USD 18 bn over the next ten years.
Private Equity scenarios. Realistically, the Life Sciences R&D Private Equity Investment In our view, key considerations for investing in similar-quality office cap rates. However, life sciences sector coupled with unavailability
requirement is estimated to be
Investment around USD 21 billion (INR 1,575 Potential in India during the current decade life sciences real estate is the value of the increase in investible universe and deepening of of core assets during the initial phase of
Opportunity billion). location and the relative market rent growth. investor pool is likely to drive compression in development is likely to drive higher rental
Life sciences cap rates are currently higher than cap rates. Further, strong growth in demand for growth offering attractive returns to investors.
While we expect the life sciences This could provide institutional
industry to benefit from strong investors with ample opportunity
Optimistic
demand drivers and the current
market environment, there are
to increase allocations to the
sector, especially in the
27 case Investment Considerations - Life Sciences R&D vs Traditional Office, India, October 2021
important investment development space. Realistically,
characteristics and considerations as per our estimates, life sciences
worth noting. research and development real Life Sciences
estate universe in India holds the Realistic R&D
Over the next decade, we estimate
the requirement of life sciences potential to attract private equity 18 case
11-16 8%-9% 138-178
research and development real institutional investment
estate universe in India to grow to amounting to USD 18 billion
somewhere between USD 16 billion (INR 1,350 billion) over the
(INR 1,200 billion) and USD 34 next ten years.
billion (INR 2,550 billion) as per Conservative
our Conservative and Optimistic 14 case Parameter Rent
Cap Rate USD Price
(USD/sq. ft./year)
per sq. ft.
Traditional
Office 14-18 7.5%-9% 187-200
Life Sciences in India:
Real Estate and Private Equity Investment Potential, Cumulative 2021 to 2030
Source : Savills India Research
Real Estate Demand (mn sq. ft.) Private Equity Investment (USD bn)
72 14 96 18 152 27
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On a Booster Dose: Life Sciences Real Estate On a Booster Dose: Life Sciences Real Estate
Life sciences R&D real estate is an emerging alternative asset class for
investors as the industry and its enabling ecosystem is resilient.
Challenges Conclusion
The life sciences real estate sector offers an attractive investment opportunity with limited cyclical risks. However, the
early growth phase does imply few challenges that investors and industry participants need to factor in while drawing
out their strategies. Life Sciences industry demand than the broader economy. In our view, life
sciences employment is well positioned from both a
is resilient near-term and long-term perspective. History suggests
The COVID-19 pandemic has brought the Life Sciences the sector’s employment base is resilient during
Political Uncertainties: sector to the centrestage. Moreover, its long-term recessionary periods. For instance, when the GDP
The growth envisaged for the life sciences sector is growth is considered relatively decoupled from the numbers depicted negative growth in 1991 (-1.1% GDP
contingent on tailwinds driven by the global political vagaries of economic cycles. growth), 2008-2009 (-0.3% and -4.1% GDP growth in
2008 and 2009 respectively) and in 2020 (-9.9% GDP
environment and supply-chain rebalancing. The Historical evidence from prior recessions suggests that growth) in the United Kingdom, the employment in life
demand for life sciences R&D may turn out to be global life sciences sector had witnessed stronger sciences sector still grew year-on-year.
lower than anticipated in case India’s positioning as
preferred pharma manufacturing / R&D destination
changes.
Life Science Employment vis-a-vis GDP Growth in the UK
Scalability: 8.00
4,500
The sector is still in early stages of evolution with
limited participants that have adequate track 4,000 6.00
record, akin to the status of the industrial and
4.00
warehousing sector a decade ago. Hence, the 3,500
sector might falter in offering the scale required 2.00
by large institutional investors at the onset. 3,000
thousands
% change
Nonetheless, we believe that investing in the 0.00
2,500
sector at present will provide a significant early
-2.00
mover advantage in terms of scalability and
2,000
tenant relationships as the sector matures over -4.00
time. 1,500
-6.00
1,000
-8.00
500 -10.00
Development Exposure:
India has limited core life sciences real estate 0 -12.00
2000
2004
2006
2008
2002
2020
1980
1990
2010
2014
1984
1994
2016
1986
1996
2018
1988
1998
2012
1982
1992
investible stock at present. Hence, majority of
the growth will come from developing new
facilities that entail typical development and Employment in human health and social work (LHS) Real GDP growth (RHS)
leasing risks. We believe that scarcity of core
stock and strong growth tailwinds will deliver Source Oxford Economics, International Monetary Fund
healthy development profits. We also foresee
increasing investor appetite for Indian life The World Economic Forum suggests that COVID-19 is could increase both to fight the current COVID-19
sciences real estate as the sector gains scale perhaps not the last pandemic, and that better pandemic, and to build a better infrastructure for
over time, which in turn bodes well for growth preparation is needed to fight future disease outbreaks. future.
investors who invest in development assets in As a result, we believe that life sciences research funding
the early phase of growth.
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On a Booster Dose: Life Sciences Real Estate On a Booster Dose: Life Sciences Real Estate
1. Scheme for Bulk Drug Parks - Notified on 21 July 2020 Example of Typical Life Sciences Building
The scheme on Promotion of Bulk Drug Parks for financing Common Switzerland Ireland Specifications in Mumbai, Maharashtra (India)
Infrastructure Facilities in three Bulk Drug Parks with financial 112,540 47,570
implication of INR 3,000 crore for 2020-2021. Assistance under the
scheme will be admissible for such facilities by State Government in Bulk Parameter Requirement
Drug Parks. Three Bulk Drug Parks will be supported under the scheme
and will have common facilities such as solvent recovery plant, distillation UK
USA
plant, power and steam units, common effluent treatment plant etc. 46,680 Ceiling
94,170 4.5 - 5 mtr
Height
2. Production Linked Incentive Scheme for Bulk Drugs (PLI 1.0)
– Notified on 21 July 2020 • 1 500 kg/sq.m. for max. of 50% total
China
The Production Linked Incentive (PLI) Scheme is launched for promotion Germany Floor built-up area
36,550
of domestic manufacturing of critical Key Starting Materials (KSMs)/ 80,410 Strength • Roof should be able to take load of chiller
Drug Intermediates (DIs) and Active Pharmaceutical Ingredients (APIs) plant & other utilities, if desired
in India. Incentives of up to INR 6,940 crores have been approved.
A financial incentive will be given to eligible manufacturers of identified Floor Plate 10,000 - 15,000 sq.ft., max. preferred
41 eligible products9 which covers 53 APIs, for 6 years, committed Australia Vietnam
investment and sales made by selected applicant for the eligible products. 69,680 15,800
The rates will vary between 5% and 20% for fermentation-based products • P
rovision for Installation of Effluent
Effluent
and chemically synthesized products. Treatment Plant (ETP)
Discharge
• Common ETP connectivity
France
3. P roduction Linked Incentive Scheme for Pharmaceuticals 60,680
Malaysia
Sewage
(PLI 2.0) - Notified on 3 March 2021 14,380
Treatment To be provided by developer
As an extension of PLI 1.0, this scheme incentivises the production of high Plant
value goods such as biopharmaceuticals, complex generic drugs, patented
India
drugs, drugs nearing patent expiry, cell based or gene therapy drugs, along Singapore 12,000 Safety Each floor should have emergency exits
with world class pharma R&D. 52,780
The objective of the scheme is to enhance India’s manufacturing
capabilities by increasing investment and production in the sector and
contributing to product diversification to high-value goods in the As per Maharashtra Industrial Development
Parking
pharmaceutical sector. One of the further objectives of the scheme is to Corporation (MIDC) regulations
Japan
create global champions out of India who have the potential to grow in 48,970
size and scale using cutting-edge technology and thereby penetrate the • G +4 or G+6, depending upon plot size and
global value chains. Incentives of INR 15,000 crores have been approved. No. of FSI
Floors • Basement, if provided, is to be used for
Additionally, the Ayushman Bharat Yojana (a centrally sponsored National installation of utilities
Health Protection programme) will provide poorer households with
affordable access to healthcare facilities, while also improving health Basic High Tension connection is to be
insurance penetration. It is estimated to benefit 13.17 crore vulnerable provided by developer; client may upgrade
Power
families (about 65 crore beneficiaries)10. As on 4th February 2021, as per their specific requirement at their
approximately 1.59 crore hospital admissions worth INR 19,714 crore have cost
been authorised through a network of 24,321 Empanelled Health Care
Providers under Ayushman Bharat - Pradhan Mantri Jan Arogya Yojana Building At least one side on road facing side should
(AB-PMJAY). This is an opportunity for the industry to help India’s Elevation have glass facade
underserved masses with affordable drugs.
Source Savills India Research
9. https://static.investindia.gov.in/s3fs-public/2020-08/PLI%20bulk%20drug%20schemes.pdf
10. https://pib.gov.in/PressReleseDetail.aspx?PRID=1696433
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Private Equity in Indian Real Estate
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