Infantile diarrhea constipation regurgitation FAP

colic

L. Reuteri √ √ √ √ √
DSM17938

Bacillus √
clausii

probiotic √

Lactobacillus √
killed

Probiotic+pre √ √
biotic

The importance of gut bacteria

Our bacteria
 Are our first line of defense against bad bacteria, pathogens
 Support and educate our immune system
 Help with digestion and absorption of nutrients
 Produce certain vitamins, like vitamin B and K
 May even affect our brain and thereby our mood
Bacteria in the human body
Our microbiota
 Consists of some 40 trillion bacteria and most of them are located in our
gastrointestinal tract
 Consists of 400-4000 different species
 Weighs up to two kg
 Is extremely essential for human health
 Being referred to as our new organ
Health starts in the gut
80% of our immune defense is located in our gut and a balanced microbiota and enough
of good bacteria is important for a well-functioning immune system. 
Ø regurgitation 67% at age 4 months
Th
Ø flatulence 56%
To achieve a healthy balance the atneedage
good bacteria 2 months
to outnumber the bad with ten to one

Ø constipation 17% of infants < 6 months

e
Ø colics/The microbiota
heavy in infants
crying 5-30% and< 6 months
of infants
children

GIT disturbances - common in infancy

 Ø im regurgitation 67% at age 4
months
Ø flatulence 56% at age 2
months
Ø constipation 17% of infants < 6
months
Ø infantile colic/ heavy crying 5-30% of
infants < 6 months

o f gThe
portance

importance of gut
bacteria

ut bactoption:
A treatment eria No treatment
Infantile Colic
DONNA M. ROBERTS, M.D., MICHAEL OSTAPCHUK, M.D., and JAMES G. O’BRIEN, M.D.
University of Louisville School of Medicine, Louisville, Kentucky

Pharmacological treatments

Drug and Therapeutics Bulletin. Management of infantile colic. BMJ 2013;40:f4102

Savino F, Tarasco V. New treatments for infant colic. Curr Opin Pediatr 2010;40(6):791–7

Simethicone:
• No difference in reducing colic episodes compared with placebo

• Not effective in resolving crises