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NCCN Guidelines for Thyroid Carcinoma V 1.

2022 – 01/26/2022

Institution Vote
Guideline Page
Panel Discussion/References ABSEN
and Request YES NO ABSTAIN
T
Based on the review of the data, the panel
consensus was to include doxorubicin/cisplatin
ANAP-A 2 of 3 as a systemic therapy option for metastatic
Comment to consider the inclusion of anaplastic thyroid carcinoma. This is a category
doxorubicin/cisplatin as a systemic therapy option 2A, useful in certain circumstances regimen.
for metastatic anaplastic thyroid carcinoma, based 19 0 6 9
on the updated ATA Guidelines for management Bible KC, Kebebew E, Brierley J, et al. 2021
of anaplastic thyroid carcinoma. american thyroid association guidelines for
management of patients with anaplastic thyroid
cancer. Thyroid 2021;31:337-386.

Based on the review of the data, the panel


consensus was that paclitaxel/carboplatin has
limited clinical use for the treatment of metastatic
ANAP-A 2 of 3 anaplastic thyroid carcinoma, and the category
Comment to reassess the continued inclusion of was changed from a category 2A (other
paclitaxel/carboplatin as a systemic therapy option recommended) regimen to a category 2B, other
for metastatic anaplastic thyroid carcinoma, based recommended regimen. 8 4 14 8
on the updated ATA Guidelines for management
of anaplastic thyroid carcinoma. Bible KC, Kebebew E, Brierley J, et al. 2021
american thyroid association guidelines for
management of patients with anaplastic thyroid
cancer. Thyroid 2021;31:337-386.

ANAP-A 2 of 3 Based on the review of the data, the panel


Comment to reassess the continued inclusion of consensus was that docetaxel/doxorubicin has
docetaxel/doxorubicin as a systemic therapy limited clinical use for the treatment of metastatic
option for metastatic anaplastic thyroid carcinoma, anaplastic thyroid carcinoma, and the category
7 4 14 9
based on the updated ATA Guidelines for was changed from a category 2A (other
management of anaplastic thyroid carcinoma. recommended) regimen to a category 2B, other
recommended regimen.
NCCN Guidelines for Thyroid Carcinoma V 1.2022 – 01/26/2022

Bible KC, Kebebew E, Brierley J, et al. 2021


american thyroid association guidelines for
management of patients with anaplastic thyroid
cancer. Thyroid 2021;31:337-386.

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