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Yuritci Martinez

Dr. Sharity Nelson

ENGL 1302-101

28 October 2022

Covid-19 Vaccines effectiveness and safety toward the community

There have been more than 100 million cases of the coronavirus illness (COVID-19 or also

known as SARS CoV-2) and many millions of fatalities. To defend against COVID-19, the Commented [LA1]: I think a fact is good introduction!

government has approved five to eight immunizations. There are several SARSCoV2 vaccines that

have received worldwide approval, including mRNA (Comirnaty and Spikevax) and viral vector

(Covid-19 Janssen and Vaxzervria). Determining the best vaccination for various demographic

groups is essential since several vaccines shown good safety profiles and considerable

effectiveness against COVID-19 in clinical studies. The SARSCoV-2 was prevented with the

Covid-19 vaccine and booster shots, which have also been reducing hospitalizations. The Covid-

19 vaccine has been shown to protect against hospitalization, help children’s and adolescents from

not getting infected. The researchers have shown that the more booster shots a someone receives, Commented [LA2]: Who? I think it would be great if you
mention what researchers
the lower their chance of being admitted. The Covid-19 vaccinations have shown that doing so

will assist the globe limit the spread of SARS-CoV-2 and prevent further deaths from occurring

globally. Additionally, regulatory, and medical choices are frequently based on benefit-risk Commented [LA3]: Take care of this format

analyses. The Covid-19 vaccine is an efficient method of preventing the disease, which can assist

to lower the risk of serious sickness and fatality, to stop the disease from spreading, and perhaps

to create herd immunity. Commented [LA4]: Good thesis statement

The Covid-19 vaccines have helped a lot of people from not getting hospitalized or even

causing death. Many people of all ages have been hospitalized in the ER because of the Covid-19
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virus and has caused them health problems. Additionally, Pfizer, AstraZeneca, Johnson &

Johnson) and boosters are among the five anti-Covid-19 immunizations that have received official

government approval. Each vaccination has a unique set of responses or side effects in human

Erazo et al. Recognize the fact that the Covid-19 vaccination is secure and has a history of lowering

hospitalizations, yet they all work well in lowering hospitalization rates, demonstrating their

effectiveness. The results "affirm the protection offered by the immunizations against the risks of

hospitalization in all age categories," (Erazo et al. 4). The second SARSCoV-2 was prevented with

the Covid-19 vaccine and booster shots, which have also been reducing hospitalizations. The

Covid-19 vaccination has been shown to protect against hospitalization, and studies have shown

that the more booster shots a person receives, the lower their chance of being admitted.

Veerle et al. agrees that the Covid-19 are safe and effectiveness for the people, but as the

other authors stated that some vaccines can have more side effects than others. “For these vaccines,

clinical trials have shown high vaccine efficacy against symptomatic infection and under real-

world circumstances, great vaccine efficacy has been established” (Veerle et al. 1). Although these

vaccinations can be both safe and efficacious, they cannot simultaneously be effective. This

finding was "supported by empirical data on the efficacy of viral vector-based vaccinations as

compared to mRNA-based immunizations against the delta variation, and it was also proven in

other assessments of emerging diseases," according to the study (9). They concluded that this

finding increased the body of knowledge on variances in the amount of protection offered by

different vaccine brands and may justify updated or new government immunization regulations.

The Covid-19 immunizations have had a significant impact since they have prevented

people from needing hospitalization, re-infecting themselves with the virus, and maybe even

dying. Since many patients have reported that the Covid-19 immunizations have kept them healthy,
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Chirico et al. believe that the vaccines are safe and effective. These vaccinations have showed

significant efficiency against the virus and extremely high levels of protection against illness,

hospitalization, and morality/deaths (Chirico et al. 92). These vaccinations demonstrated both a

very high level of protection against sickness, hospitalization, and mortality as well as great

effectiveness against the infection.

Therefore, it has been established that these immunizations are both efficient and safe for

everyone, but not everyone is the same. Liu et al. evaluate the "Covid-19 vaccine's effectiveness

and safety" in the real world (3). Vaccinations against Covid-19 are safe and effective, according

to Liu et al., and they will help avoid hospitalization, infections, admission to the ICU or

Emergency department, and mortalities. Worldwide, coronavirus vaccines are extremely safe and

have the potential to drastically reduce the number of virus-related illnesses, infections, and

fatalities” (1). The researchers found that while two doses of a vaccination might have moderate

side effects, they are more effective than other immunizations.

Chen et al., believes that the Covid-19 vaccinations are safe and could progressively lower

the number of infections, deaths, and the other Covid-19 related illnesses around the world. Two

doses of the Covid-19 vaccine had an effectiveness of 85% or higher (Chen et al. 9). Although

immunizations against strains of the SARS-CoV-2 virus were less effective than the initial strain,

they were still more than 50% effective in those who had received all available vaccinations (Chen

et al. 9). The results of the study showed that while various immunization types are usually safe

and effective, certain vaccinations may nonetheless have more adverse effects than others. These

immunizations helped the virus spread less widely and significantly reduced the number of

mortalities among persons of all ages.

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Most of the vaccines showed a good safety profile and significant efficacy against Covid-

19. The researchers wanted to examine how efficacy each Covid-19 vaccine is and for every

vaccine they did trials to make sure they are safe. They examined first Moderna, AstraZeneca,

CoronaVac, Baharat, Sinopharm, Clover, Casino, CureVac, and ZyCov-D vaccines only. These

vaccines tested to be more effective in preventing Covid-19 infection. Sinopharm and Sputnik

vaccines exhibited the highest safety profile and most effectives. Toubasi et.al stated that “In the

elderly population it is important to balance between the safety and efficacy for each individual”

(259). The researchers revealed that Pfizer was the most effective toward the elderly population.

The researchers wanted to examine four vaccines, which are Pfizer, Moderna, AstraZeneca,

and Sinovac. These four vaccines have low safety risk and have higher efficacy of 95%,44%,70%

and 78%. Also, these vaccines are effective and save, but they can show some adverse effects.

Most of the adverse effect were caused by the second dose. The AstraZeneca Covid-19 vaccine Commented [LA5]: "Also, these vaccines are effective and
safe, but they can show some adverse effects, mostly causes
by the second dose."
was not safe nor effective for the people. The government banned the use of these vaccine because

it was causing blood clots. The Sinopharm vaccine has been approved as a 2-dose vaccine for

prevention of Coronavirus and this vaccine has help people from not getting infected. The Pfizer

vaccines is the most popular and has a 95% efficacy against the Covid-19 virus. The Sputnik V

vaccine has efficacy of 91.6% and has help a lot of people with lowering the side effects.

The Covid-19 vaccine is an efficient method of preventing the disease, which can assist to

lower the risk of serious sickness and fatality, to stop the disease from spreading, and perhaps to

create herd immunity. These vaccines have been widely used on the adult’s population and try it

with some younger generation. The Covid-19 vaccines has helped the children’s and adolescents

to have less chance of getting infected or get another type of virus because the vaccines are helping

them to not get sick again. “According to a prior study, people who received mRNA vaccinations Commented [LA6]: Connect this sentences.
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in full or in part were protected against Covid-19 in 91% of cases and in 81% of cases,

respectively” (Tian et al. 4652).

Worldwide, the Covid-19 sickness claimed many lives and infected many more. Many

people have demonstrated the safety and efficacy of the Covid-19 vaccines. Covid-19 vaccines are

safe and effective for everyone. The Covid-19 vaccines were evaluated by different people to make

sure they are safe and effective for the community. The clinical trials used to assess and approve

Covid-19 vaccinations shown that the vaccine considerably lowers the risk of getting the virus.

Even if you contract the virus, the Covid-19 vaccination may help prevent you from becoming

extremely unwell, according to what has been demonstrated concerning vaccines for other

illnesses. Getting vaccinated may help protect individuals close to you, especially those who are

more susceptible to Covid-19's severe disease. Regardless of whether people have favorable or

unfavorable experiences and perspectives, they should get vaccinated for the safe of everyone.

This study suggests that patients should receive Covid-19 vaccines to help prevent mortality or

other diseases, allowing them to lead normal lives without worrying about catching the disease

again. Commented [LA7]: Try using transition words to make

connect your sentences
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Works Cited

Chen, Yamin, et al. “Covid-19 Vaccine Research Focusses on Safety, Efficacy,

Immunoinformatics, and Vaccine Production and Delivery: A Bibliometric

Analysis Based on VOSviewer.” BioScience Trends, vol. 15, no. 2, 2021, pp.

64–73., https://doi.org/10.5582/bst.2021.01061.

Chirico, Francesco, et al. “Safety & Effectiveness of COVID-19 Vaccines: A

Narrative Review.” Indian Journal of Medical Research, vol. 155, no. 1, Jan.

2022, pp. 91–104., https://doi.org/10.4103/ijmr.ijmr_474_21.

Liu, Qiao, et al. “Effectiveness and Safety of SARS-COV-2 Vaccine in Real-

World Studies: A Systematic Review and Meta-Analysis.” Infectious

Diseases of Poverty, vol. 10, no. 1, 14 Nov. 2021, pp. 1–15.,

https://doi.org/10.1186/s40249-021-00915-3.

Erazo, Diana, et al. “Investigating Covid-19 Vaccine Impact on the Risk of

Hospitalisation through the Analysis of National Surveillance Data Collected

in Belgium.” Viruses, vol. 14, no. 6, 16 June 2022, pp. 2–8.,

https://doi.org/10.3390/v14061315.
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Tian, Fangyuan, et al. “Safety and Efficacy of Covid‐19 Vaccines in Children and

Adolescents: A Systematic Review of Randomized Controlled

Trials.” Journal of Medical Virology, vol. 94, no. 10, 2022, pp. 4644–4653.,

https://doi.org/10.1002/jmv.27940.

Qamar, Naila, et al. “Vaccines for Covid‐19: An Insight on Their Effectiveness and

Adverse Effects.” Journal of Medical Virology, vol. 94, no. 8, 2022, pp.

3554–3560., https://doi.org/10.1002/jmv.27810.

Toubasi, Ahmad A., et al. “Efficacy and Safety of Covid‐19 Vaccines: A Network

Meta‐Analysis.” Journal of Evidence-Based Medicine, vol. 15, no. 3, 2022,

pp. 245–262., https://doi.org/10.1111/jebm.12492.

Yang, Bingyi, et al. “Immunogenicity, Efficacy, and Safety of SARS-COV-2

Vaccine Dose Fractionation: A Systematic Review and Meta-Analysis.” BMC

Medicine, vol. 20, no. 1, 2022, https://doi.org/10.1186/s12916-022-02600-0.