BARTOLOME, RHOEL JOHN V

BSN 4B

DRUG STUDY

Omepron
Contents Indications Dosage Omeprazole Listed in Dosage. Active duodenal ulcer & GERD w/ erosive esophagitis 20 mg once daily for 4-8 wk. Gastric ulcer 40 mg once daily for 4-8 wk. Symptomatic GERD w/o esophageal lesions 20 mg once daily for up to 4 wk. Maintenance of healing of erosive esophagitis 20 mg once daily for up to 12 mth.Pathological hypersecretory conditions eg Zollinger-Ellison syndromeInitially 60 mg once daily. Max: 120 mg tid in divided doses. H. pylorieradication in peptic ulcer disease Triple therapy: 20 mg Omepron bid, 500 mg clarithromycin bid & 1000 mg amoxicillin bid, or 20 mg Omepron bid, 250 mg clarithromycin bid & 500 mg metronidazole/tinidazole bid, or 40 mg Omepron once daily, 500 mg amoxicillin tid& 500 mg metronidazole/tinidazoletid. Treat for 10 days. Dual therapy: 40 mg Omepron once or bid + 500 mg clarithromycin or 500 mg amoxicillin tid. Treat for 14 days. Should be taken with food (Take immediately before a meal.). Symptomatic response to therapy does not rule out presence of gastric malignancy. Pregnancy & lactation. Click to view Omepron detailed prescribing infomation Constipation, diarrhea, flatulence, nausea, vomiting & acid regurgitation. Abdominal pain, asthenia, headache, dizziness, rash. Increase metabolism & prolong elimination of diazepam, warfarin,carbamazepine, phenytoin & other drugs metabolized by oxidation in the liver. Interfere w/ absorption of ketoconazole, ampicillin esters & iron salts.

Administration Special Precautions

Adverse Drug Reactions Drug Interactions

MIMS Class ATC Classification

Antacids, Antireflux Agents &Antiulcerants A02BC01 - Omeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

BARTOLOME, RHOEL JOHN V

BSN 4B

DRUG STUDY

Cefuroxime
Indications Dosage Listed in Dosage. Adult: PO Uncomplicated UTI 125 mg twice daily. Resp tract infections250-500 mg twice daily. Uncomplicated gonorrhoea W/ oral probenecid: 1 g as a single dose. IV Meningitis 3 g 8 hrly. IM Gonorrhoea W/ oral probenecid: 1.5 g as a single dose. IV/IM Surgical prophylaxis 1.5 g IV per-op, then 750 mg IM 8 hrly for up to 24-48 hr. Susceptible infections 750 mg 8 hrly, up to 1.5 g 6-8 hrly for severe infections. Should be taken with food. Hypersensitivity to cephalosporins. Severe renal impairment; pregnancy, lactation; hypersensitivity to penicillins. Large doses can cause cerebral irritation and convulsions; nausea, vomiting, diarrhoea, GI disturbances; erythema multiforme, Stevens-Johnson syndrome, epidermal necrolysis. Potentially Fatal: Anaphylaxis, nephrotoxicity, pseudomembranous colitis. Probenecid decreases renal clearance of cefuroxime. Potentially Fatal: Nephrotoxicity with aminoglycosides and furosemide. Cephalosporins J01DC02 - Cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.

Administration Contraindications Special Precautions Adverse Drug Reactions

Drug Interactions

MIMS Class ATC Classification