Patient’s Profile

Name: Mr. x
Age: 47
Occupation: CArpenter
Gender: Male
Past Health History:
Patient X had several symptoms, including indigestion, loss of appetite, abdominal pain, and oily diarrhea. The abdominal pain
was relieved temporarily by eating and by taking OTC antacids. He saw his primary care physician, who referred him to a
gastroenterologist.
Past Medical History:
(Surgery done)
1. Fiberoptic endoscopy, which showed an ulcer in the duodenal bulb.
2. Laparoscopic surgery, during which the tumor was localized and removed. Jonas’s ulcer subsequently healed, and his
symptoms disappeared.
Laboratory Result:
To determine the cause of the ulcer (No date indicated for this lab test date)
HIGH
HIGH
HIGH
CT SCAN RESULT:
3-cm mass in the tail of the pancreas. Initial impression: Gastrinoma. Final diagnosis: Zollinger-Ellison syndrome.
Definition of Terms: A-Z
1. Fiberoptic endoscopy- formal evaluation which involves placing a flexible scope through the nasal
passageway and into the pharynx in order to observe the pharynx and larynx before and after a swallow
2. Gastrinoma- rare tumors forming in the pancreas or duodenum, which is the first part of the small intestine.
3. Laparoscopic surgery- a kind of exploratory surgery using a laparoscope
4. Tumor- is a mass or group of abnormal cells that form in the body.
5. Ulcer- are sores on the lining of your stomach or small intestine.
6. Zollinger-Ellison syndrome- is a rare condition in which one or more tumors grow in the pancreas or in the
upper part of the small intestine. The tumors are called gastrinomas.
 Zollinger-Ellison syndrome
MR. X G cells in the pancreas or duodenum
develop a mutation which makes them
divide uncontrollably

Gastrinoma

Hypergastrinemia

Hypertrophy of gastric
mucosa
Increased number of parietal
cells
Increased acid
production

Increased maximal acid

output
Pancreatic Lipase
Inactivated
Gastric Ulceration Bowel mucosal
injury

Indigestion
Abdominal Pain

Diarrhea Malabsorption

Loss of appetite