GENERIC MECHANISM INDICATION CONTRAINDICATION SIDE NURSING

NAME OF ACTION EFFECTS CONSIDERATION

Nitrofurantoin oral Macrodantin is Macrodantin is Macrodantin is Chronic, Assess any breathing

capsule a synthetic specifically contraindicated in subacute, or problems or signs of
chemical of indicated for the patients with a previous acute pulmonary pneumonitis such as
Brand name: controlled treatment of urinary history of cholestatic hypersensitivity cough, shortness of
Macrodantin crystal size. It tract infections jaundice/ hepatic may occur. breath, fever, rales,
is a stable, when due to dysfunction associated chest pain, and
Classification: yellow, susceptible strains with nitrofurantoin. Asthenia difficult, labored
Antibiotics crystalline of Escherichia coli, Vertigo breathing. Monitor
compound. enterococci, Macrodantin is also Dizziness pulse oximetry and
Dosage: 100 mg Macrodantin is Staphylococcus contraindicated in those Headache perform pulmonary
four an antibacterial aureus, and certain patients with known Drowsiness function tests.
times daily. agent for susceptible strains hypersensitivity to
specific urinary of Klebsiella and nitrofurantoin.
tract infections. Enterobacter
It is available in species.
25 mg, 50 mg,
and 100 mg
capsules for
oral
administration.
 GENERIC MECHANISM INDICATION CONTRAINDICATION SIDE NURSING
NAME OF ACTION EFFECTS CONSIDERATION

Amoxicillin AUGMENTIN is To reduce the AUGMENTIN is Anaphylactic

clavulanate acid an oral development of drug contraindicated in reactions Assess respiratory
antibacterial resistant bacteria and patients with a history status.
Brand Name: combination maintain the of serious Hepatic
Augmentin consisting of effectiveness of hypersensitivity Dysfunction Observe for
amoxicillin and AUGMENTIN reactions (e.g., anaphylaxis.
Classification: the beta- (amoxicillin/clavulanate anaphylaxis or Stevens-
Antimicrobials lactamase potassium) and other Johnson syndrome) to
and Penicillin. inhibitor, antibacterial drugs, amoxicillin, clavulanate
clavulanate AUGMENTIN should be or to other beta lactam
Dosage: potassium (the used only to treat antibacterial drugs
250 mg four potassium salt infections that are (e.g., penicillins and
times daily. of clavulanic proven or strongly cephalosporins).
acid). suspected to be
caused by susceptible
bacteria. When culture
and susceptibility
information are
available, they should
be considered in
selecting or modifying
antibacterial therapy.
In the absence of such
data, local
epidemiology and
susceptibility patterns
may contribute to the
empiric selection of
therapy.