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SYSTEMATIC REVIEWS
Professor F. E. Afolabi LESI FNAMed, FAMedS
Department of Paediatrics,
College of Medicine, University of Lagos
OBJECTIVES
At the end of the session it is expected that participants should:
• Define what a systematic review is and note the differences from a
traditional review.
• Outline the systematic review process.
• Describe how the knowledge can be applied in appraising evidence
for healthcare decision making.
SEARCH Loading dose Index and free text search for: Randomised
STRATEGY High first dose Malaria Controlled Trial
Quinine (ti:ab)
Controlled clinical
trial
Double blind
PERFORMANCE BIAS Blinding of participants and personnel, Other potential threats to validity
Overall
Effectiveness
33
CONCLUSION
• Systematic reviews are rigorous and scientifically sound. It is now
being regarded and published as original research in reputable
journals.
• Doing a systematic review is a continuous iterative process. Evidence
is never final.
• It forms the basis of evidence based medicine and are an integral part
of improving clinical practice.