38 Revisao de plantas brasileiras com comprovado efeito hipoglicemiante no controle do Diabetes mellitus Volpato, G.7.'; Damasceno, D.C. ‘alderon, |. M. ; Rudge, M.V.C.> “Dept. de Ginecologia e Obstetricia/UNESP/Campus de Botucatu, Distrito de Fubido Jr, CEP 18616-000, Botucalu/SP, e-mail: givolpato @zipmail,com,br, “Faculdade de Medicina de Marilia (FAMEMA), Marilia/SP. RESUMO: Cs vagetais sie utiizados na cura de doencas desde os priméidios da humanidade Hoje em dia, no Brasil, sou uso é comum devido princpalmente ao cific acesso da populagzo & ascieténcia médica. E comum 0 pensamento de que 2 plantas madicinais do use tradiconel ja foram testades © homologadas pelo uso protongado na espécie humana, sendo considerados remédios eficazes e que no apresontam eels colalerais, nfo necessiiando, portant, de avaliagao, ‘A automedicagdo milagrosa com plantas mecicinais chega ao extromo de substivirterapias em doengas graves como, pot exemplo, as de efeito hipoglicemiantas ou anidiabstcas. Para o tesio de plantas medicinais, tom que ser levado em conta a qualidade do material a ser testado, parte da planta uilizada, métedo de extracso @ a dose @ aspécie da experimentacao utlizedos. Diversas plantas jd iveram seus eletes hipogicemianies comprovados experimentalmerte. O objetivo desie trabatho foi realizar uma revisdo de plantas medicinaisbrasileras ulizadas popularmente, como hipogliceriantes que tiveram seus eletes comprovados em animais @ no homem Palavras-chave: planias medicinais, diabetes mellitus, hipoglicémicos ABSTRACT: Review of Brazilian plants with proven hypoglycemic effectn the control of Diabetes. ‘mellitus. Plants have been used in the cure of diseases {rom the origins of the humanity. At present, in Brazil the use is commen because of the difieity of accass of part othe population to medical assistance. itis commonly believed that the that the medicinal plants of tractionel use were already tested and ratified by the longrlasting use by the human species, being considered effective mecicines, presenting no collateral effects, not needful, therefore, of evaluation, The miraculous sell-medication with medicinal plants goes to the point of substituting therapies in serious diseases such as those of hypoglyceme or anti Tego agus | — |v | woe 1 | Qcoimam abun | Pere” | Fama | Aqucso | 25mokg | vo. | Aarawa tat, 1996 Corum cancion | Manioicio | Fahne | Thue | eS | V3 | “Sera tox ome Frqveiada | Cauje | capsula | 335mgcaps | vo. | Muna tat, 1982 Parthos Quebrapadra | Folha | Aquaso _ wo. baie fallen j Trgonelatenu | eenoereqo | Semerte Nacdeta | 1009 | vo. | Sama etal 1980 graccun Semente Nadie] 125g | [Nea again 0. via oral Uma vez estabelecido 0 grau de confianga do ponto de vista toxicol6gico, e comprovada sua seguranga, € possivel que essas plantas possam ser usadas como terapéutica complementar da terapia convencional do diabete. Embora soja improvavel que um substiiio botdnico, oralmente ativo, vanha mimetizara apace a insulina, 08 extratos ou principics ativos de plantas, com ago estimulante na biossintese e ‘sectaeao de insulina endégena (2 conseqiente promogao de sua agao), sa0 possibilidades reais (Bailey & Day, 1989). A idéia primordial na indicagao de fitoterapicos nao @ substituir medicamentos registrados e j4 comercializados, mas sim ‘aumentar a opgao terapéutica dos profissionais de salide, considerando-se a reducaa dos custos (Lapa et a/, 1999) e os beneficios de uma agao coadjuvante, potencializadora da terapia convencional. REFERENCIABIBLIOGRAFICA ABDEL-BARRY, J.A., ABDEL-HASSAN, LA, AL-HAKIEN, N.H.H. Hypoglycaamic and antihyperglycaemic ‘etfecis of Trigonelia foenum-graceurn eal in normal land alloxan induced diabetic rats, Journal of Ethnopharmacology, v.58, p.149:55, 1997. AQDEL-HASSAN, LA,, ABDEL-BARRY, JA, TARIQ MOHAMMEDA, 8. 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