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  • Protein Degradation

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    Afrin Ibrahim
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    The document discusses protein degradation in prokaryotes and eukaryotes. In prokaryotes, protein degradation involves proteases that directly cleave proteins. In eukaryotes, protein degradation involves two systems: the ubiquitin proteolytic system where ubiquitin is activated and attached to target proteins, and the polyubiquitin system where ubiquitin molecules are attached to each other on the target protein. The document was written by V. Priscilla Pushparani from the Department of Biotechnology at St. Peter's College of Engineering & Technology in Avadi, Chennai.

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    PROTEIN DEGRADATION

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    The document discusses protein degradation in prokaryotes and eukaryotes. In prokaryotes, protein degradation involves proteases that directly cleave proteins. In eukaryotes, protein degradation involves two systems: the ubiquitin proteolytic system where ubiquitin is activated and attached to target proteins, and the polyubiquitin system where ubiquitin molecules are attached to each other on the target protein. The document was written by V. Priscilla Pushparani from the Department of Biotechnology at St. Peter's College of Engineering & Technology in Avadi, Chennai.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    8 views9 pages

    Protein Degradation

    Uploaded by

    Afrin Ibrahim
    The document discusses protein degradation in prokaryotes and eukaryotes. In prokaryotes, protein degradation involves proteases that directly cleave proteins. In eukaryotes, protein degradation involves two systems: the ubiquitin proteolytic system where ubiquitin is activated and attached to target proteins, and the polyubiquitin system where ubiquitin molecules are attached to each other on the target protein. The document was written by V. Priscilla Pushparani from the Department of Biotechnology at St. Peter's College of Engineering & Technology in Avadi, Chennai.

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    © All Rights Reserved
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    of 9

    PROTEIN DEGRADATION

    (BIOCHEMISTRY UNIT -5)

    By

    v.Priscilla pushparani
    Assistant professor

    Department of biotechnology
    St.Peter’s college of Engineering & Technology
    Avadi,Chennai
    PROTEIN DEGRADATION IN PROKARYOTICS

    PROTEIN DEGRADATION IN EUKARYOTICS


    The degradation in eukaryotics is divided in to two system:

    (i) Ubiquitin proteolytic system


    (ii) Polyubiquitin system
    Ubiquitin proteolytic system

    Activation and attachment of ubiquitin to a protein


    targeted for degradation in eukaryotes
    Polyubiquitin system
    THANK YOU

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