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Sas 13 MC PDF
Sas 13 MC PDF
Materials:
LESSON TITLE: DISORDERS OF PITUITARY AND THYROID Book, pen and notebook, projector
GLANDS
LEARNING OUTCOMES:
Upon completion of this lesson, the nursing student can:
1. Differentiate the clinical manifestations of the disorders.
2. Identify the different medical and nursing management of the References:
disorders.
Smeltzer, S., Bare, B., Hinkle, J., & Cheever, K.
3. Recognize the characteristics of each disease.
(2008). Brunner &Suddarth’s Textbook of
4. Determine the appropriate nursing diagnoses of each
Medical-Surgical Nursing 12th Edition.
disease.
Lippincott Williams &Wilkins
5. Identify the medical-surgical and nursing management of
pituitary and thyroid tumors.
Clinical Manifestations
1. Eosinophilic tumors
- Occurs early in life: gigantism: more than 7 feet tall and large in all proportions; weak and lethargic; can
hardly stand
- Occurs during adult life: acromegaly: excessive skeletal growth in the feet, hands, superciliary ridge, molar
eminences, nose, and the chin
- Enlargement involves all tissues and organs; severe headaches; visual disturbances (central vision and
visual fields may reveal loss of color discrimination, diplopia, or blindness in a portion of a field of vision)
- Decalcification of the skeleton; muscular weakness; and endocrine disturbances, similar to those occurring
in patients with hyperthyroidism, also are associated with this type of tumor.
2. Basophilic tumors
- Give rise to Cushing’s syndrome with features largely attributable to hyperadrenalism, including
masculinization and amenorrhea in females, truncal obesity, hypertension, osteoporosis, and polycythemia
3. Chromophobic tumors
- Represent 90% of pituitary tumors; usually produce no hormones but destroy the rest of the pituitary gland,
causing hypopituitarism
- People with this disease are often obese and somnolent and exhibit fine, scanty hair; dry, soft skin; a pasty
complexion; and small bones.
- They also experience headaches, loss of libido, and visual defects progressing to blindness. Other signs
and symptoms include polyuria, polyphagia, a lowering of the basal metabolic rate, and a subnormal body
temperature.
Medical Management
1. Stereotactic radiation therapy
- Used to deliver external beam radiation therapy precisely to the pituitary tumor with minimal effect on normal
tissue.
2. Other treatments
a. Conventional radiation therapy
b. Medications like Bromocriptine (Parlodel, a dopamine antagonist), and Octreotide (Sandostatin, a synthetic
analogue of GH).
- These medications inhibit the production or release of GH and may bring about marked improvement
of symptoms.
- Octreotide and Lanreotide (Somatuline Depot, a somatostatin analogue) may also be used
preoperatively to improve the patient’s clinical condition and to shrink the tumor.
Surgical Management
Hypophysectomy
Surgical removal of the pituitary tumor through a transsphenoidal (endoscopic transnasal)
approach is the usual treatment.
SIADH DI
Excessive secretion of antidiuretic hormone (ADH) – Characterized by a deficiency of antidiuretic hormone
vasopressin. Characterized by inability to excrete dilute (vasopressin), leading to polydipsia and large volumes of
urine, retention of fluids, and a dilutional hyponatremia dilute urine.
Causes Causes
bronchogenic carcinoma in which malignant lung cells head trauma, brain tumor, surgical ablation, or irradiation of
synthesize and release ADH; head injury; brain surgery or posterior pituitary gland, meningitis, encephalitis,
tumor, and infection; medications: Vincristine (Oncovin), nephrogenic forms: hypokalemia, hypercalcemia, lithium,
Phenothiazines, Tricyclic antidepressants, Thiazide demeclocycline
diuretics
Nursing Management
1. Monitor vital signs
2. Daily weights
3. Monitor intake and output
4. Monitor serum electrolytes
5. Observe signs of dehydration
6. Monitor urine values
7. Encourage medical bracelet alert
Medical Management
1. Supplementary iodine, such as SSKI to suppress the pituitary’s thyroid-stimulating activity.
2. Ensure a preoperative euthyroid state through treatment with antithyroid medications and iodide to
reduce the size and vascularity of the goiter before surgery to minimize postoperative complications.
3. Provide children in iodine-poor regions with iodine compounds to prevent simple or endemic goiter.
Introduction of iodized salt has been the single most effective means of preventing goiter in at-risk
populations.
NODULAR GOITER
Some thyroid glands are nodular because of areas of hyperplasia (overgrowth). No symptoms may arise
as a result of this condition, but not uncommonly these nodules slowly increase in size, with some descending into
the thorax, where they cause local pressure symptoms. Some nodules become malignant, and some are associated
with a hyperthyroid state. Therefore, the patient with many thyroid nodules may eventually require surgery.
THYROID CANCER
Cancer of the thyroid is much less prevalent than other forms of cancer; however, it accounts for 90% of
endocrine malignancies.
- With one fourth of the cases occurring in men and three fourths in women.
- External radiation of the head, neck, or chest in infancy and childhood increases the risk of thyroid
carcinoma. The incidence of thyroid cancer appears to increase 5 to 40 years after irradiation.
Surgical Management
Total or Near-total Thyroidectomy
- The treatment of choice for thyroid carcinoma is surgical removal.
- Efforts are made to spare parathyroid tissue to reduce the risk of postoperative hypocalcemia and
tetany.
HYPERTHYROIDISM HYPOTHYROIDISM
Excessive secretion of thyroid hormones. It is the second A deficiency in thyroid hormones
most prevalent endocrine disorder, after diabetes mellitus. Types
1. Primary Hypothyroidism
Graves’ disease: the most common type of 2. Secondary/Pituitary Hypothyroidism
hyperthyroidism 3. Tertiary/Hypothalamic Hypothyroidism
4. Cretinism
Thyroid Storm:
5. Electrocardiographic (ECG) monitoring
6. ABG analysis
7. Pulse oximetry
8. Oxygen administration
9. IV fluids
10. Antipyretic
11. Cooling blanket
12. Patent airway
Surgical Management
Performed soon after the thyroid function has returned to
normal (4 to 6 weeks). Administration of PTU, Iodine
solutions, and Beta-blockers before surgery is needed.
Thyroidectomy
- needs thyroid hormone and calcium replacement
after surgery
- hormone levels should be monitored every 6 weeks
Complications: Hypothyroidism; Hypocalcemia;
Hypoparathyroidism
Multiple Choice
(For 1-15 items, please refer to the questions in the Rationalization Activity)
RATIONALIZATION ACTIVITY (DURING THE FACE TO FACE INTERACTION WITH THE STUDENTS)
The instructor will now rationalize the answers to the students (including Quiz activity) and will encourage them to ask
questions and to discuss among their classmates for 20 minutes.
1. When caring for a male client with diabetes insipidus, nurse Juliet expects to administer:
A. Vasopressin (Pitressin Synthetic).
B. Furosemide (Lasix).
C. Regular insulin.
2. Nurse Louie is developing a teaching plan for a male client diagnosed with diabetes insipidus. The nurse should include
information about which hormone lacking in clients with diabetes insipidus?
A. Antidiuretic hormone (ADH).
B. Thyroid-stimulating hormone (TSH).
C. Follicle-stimulating hormone (FSH).
D. Luteinizing hormone (LH).
ANSWER: ________
RATIO:___________________________________________________________________________________________
_________________________________________________________________________________________________
____________________________________________________
3. Which outcome indicates that treatment of a male client with diabetes insipidus has been effective?
A. Fluid intake is less than 2,500 ml/day.
B. Urine output measures more than 200 ml/hour.
C. Blood pressure is 90/50 mm Hg.
D. The heart rate is 126 beats/minute.
ANSWER: ________
RATIO:___________________________________________________________________________________________
________________________________________________________________________________________________
_____________________________________________________
4. An incoherent female client with a history of hypothyroidism is brought to the emergency department by the rescue squad.
Physical and laboratory findings reveal hypothermia, hypoventilation, respiratory acidosis, bradycardia, hypotension, and
nonpitting edema of the face and pretibial area. Knowing that these findings suggest severe hypothyroidism, nurse Libby
prepares to take emergency action to prevent the potential complication of:
A. Thyroid storm
B. Cretinism
C. Myxedema coma
D. Hashimoto’s thyroiditis
ANSWER: ________
RATIO:___________________________________________________________________________________________
_________________________________________________________________________________________________
____________________________________________________
5. Vasopressin is administered to the client with diabetes insipidus (DI) because it:
A. Decreases blood sugar.
B. Increases tubular reabsorption of water.
C. Increases release of insulin from the pancreas.
D. Decreases glucose production within the liver.
ANSWER: ________
RATIO:___________________________________________________________________________________________
_________________________________________________________________________________________________
____________________________________________________
6. A male client is admitted for treatment of the syndrome of inappropriate antidiuretic hormone (SIADH). Which nursing
intervention is appropriate?
A. Infusing I.V. fluids rapidly as ordered.
B. Encouraging increased oral intake.
C. Restricting fluids.
D. Administering glucose-containing I.V. fluids as ordered.
ANSWER: ________
RATIO:___________________________________________________________________________________________
________________________________________________________________________________________________
_____________________________________________________
9. A client represents with flushed skin, bulging eyes, and perspiration, and states that he has been irritable and having
palpitations. This client is presenting with symptoms of which disorder?
A. Pancreatitis
B. Hypothyroidism
C. Hyperthyroidism
D. Diabetes insipidus
ANSWER: ________
RATIO:___________________________________________________________________________________________
________________________________________________________________________________________________
_____________________________________________________
10. The appropriate nursing diagnosis for a patient with SIADH is:
A. Fluid volume deficit related to excessive fluid loss
B. Fluid volume excess related to fluid retention
C. Risk for injury related to decreased blood pressure
D. Impaired skin integrity related to dehydration
ANSWER: ________
RATIO:___________________________________________________________________________________________
_________________________________________________________________________________________________
____________________________________________________
11. A male client has recently undergone surgical removal of a pituitary tumor. Dr. Wong prescribes corticotropin (Acthar),
20 units I.M. q.i.d. as a replacement therapy. What is the mechanism of action of corticotropin?
A. It decreases cyclic adenosine monophosphate (cAMP) production and affects the metabolic rate of target organs.
B. It interacts with plasma membrane receptors to inhibit enzymatic actions.
C. It interacts with plasma membrane receptors to produce enzymatic actions that affect protein, fat, and carbohydrate
metabolism.
D. It regulates the threshold for water resorption in the kidneys.
ANSWER: ________
RATIO:___________________________________________________________________________________________
_________________________________________________________________________________________________
____________________________________________________
12. A female client whose physical findings suggest a hyperpituitary condition undergoes an extensive diagnostic workup.
Test results reveal a pituitary tumor, which necessitates a transsphenoidal hypophysectomy. The evening before the
surgery, nurse Jacob reviews preoperative and postoperative instructions given to the client earlier. Which postoperative
instruction should the nurse emphasize?
A. “You must lie flat for 24 hours after surgery.”
B. “You must avoid coughing, sneezing, and blowing your nose.”
13. A somatotropin-secreting tumor of which of the following glands would lead to the development of acromegaly, Cushing’s
syndrome, and hypopituitarism?
A. Adrenal gland
B. Hypothalamus
C. Pituitary gland
D. Thyroid gland
ANSWER: ________
RATIO:___________________________________________________________________________________________
_________________________________________________________________________________________________
____________________________________________________
14. Surgical management for large, invasive pituitary tumors is a transphenoidal hypophysectomy. The nurse would explain
that the surgery will be performed through an incision in the:
A. Nose
B. Back of the mouth
C. Sinus channel below the right eye
D. Upper gingival mucosa in the space between the upper gums and lip
ANSWER: ________
RATIO:___________________________________________________________________________________________
_________________________________________________________________________________________________
____________________________________________________
15. Initial treatment for a CSF leak after transphenoidal hypophysectomy would most likely involve:
A. Repacking the nose.
B. Returning the client to surgery.
C. Enforcing bed rest with the head of the bed elevated.
D. Administering high-dose corticosteroid therapy.
ANSWER: ________
RATIO:___________________________________________________________________________________________
_________________________________________________________________________________________________
____________________________________________________
You are done with the session! Let’s track your progress.
Quiz
A. Answer the items below.
Instruction: Write A – for SIADH, and B – for DI. Write your answers on the spaces provided.
1. excessive vasopressin:
2. hypotension:
3. weight gain:
4. deficient vasopressin:
5. rales:
B. Instruction: Match the symptoms. Put an arrow next to the sign or symptom.
Arrow up = hyperthyroidism
Arrow down = hypothyroidism