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Cefriaxone + hjentbie ds ro carmot be ved for masser 1 Safein sregnany anderen Gen + Cetuorine 2 Gettin + Cetmetsti0 1 cetamandole Il O Q A Crotoxain {Citi pregnancy an eeen + Cante sven oly + DOC for Mars hero prophylaxis of esingococe! meningitis Gen sen + Celie + Ceftirte catprome 2 Cftarolne 189 PROTEIN SYNTHESIS INHIBITORS < Scanned with CamScannerSemlsynthete Natural s AAntipseudomonal Scanned with CamScanner Z | Aer of activity Similar 10 Ampiciln, huts Pseudomonas aera ‘See maura penicitins +S. Peniciinse-producing staphylococci (RSA) of diphheria,antax 1 Spt ares 1 ¥e fo» Bee Lise oy gd sporeforming anaerobes 1. Diseases caused by tracts infections, 2. Hospital infections Side effects Alera headache, nausea, vomiing, pseudomembranous W administration itn snistration, phi Contraindications | | Allergy, 1 semester of pregnancy (amon mwo-micoorpniong ily ~intravenous s a ~ 3 , ae es 5 co Ce y res Me ie Si YY .» ey ¢ ae;| , OXAZOLIDINONS AND FUZIDIC ACID 2 24) GLYCOPEPTIDES, OXAZOI ‘Chssineaton > Giycopeptides generation Droxs Inceolid(zivox) Mechanism of action ‘Spectrum Indications Side effects hepatotoxicity, reversible ane eytopenia function, te Scanned with CamScanner(Chasitication Natural Ho Polymyxin Drugs 1. Lincomyin| 7 = Gaya abe 7] lymyxin M. 3.Polymyuin F (eo ‘Mechanism of action ls protcin inthe ribosomes (bac- on) Violate the integriy of the cytoplasmic membrane of the action) ‘microbial cell (bacteriidat Spectrum of action Gres) cocei 2. Anaerobes( Diff iaphylococci (except MRSA, steptocose,preumococei 1. Gr(.) bacteria: Ecol, Salmonella, Shigella. Klee, Enlcrobactera, Pseudomonas aeruginosa, 2, Anaerobes:Fusobostria and becle les are moderately senslive Taaiations 1A dg of tat reo or esta pcudoras nestor eee grameqave Heusine(i3y ne ey weg Ae antl an Side effects development of hed ad hematuria) newotovcty | blood eae | ae development of the respiratory mus- Je iy Wwonbopogena hylaemaapeckema | Kida, Conteaindieations| Not toxicity, and with neuromuscular blockers ~ neu ‘administration of polymyxin with aninoglycosides increases its ne- muscular tansmssion is Blood — ons = GD - cl Reh all ath pale pote Scanned with CamScannerCARBAPENEMS AND MONOBACTAMS — ae lesb rere enbbabs “— Clasitication Monobactams An Drugs ‘3. Aztreonam ‘Mechanism oF action ‘Spectrum of activity ‘ora: gonococeus, meningococeus, Escherichia coli Salmonella, Shigel= 1a, Klebsela, Proteus, Citrobacterium, Pseudomonas aeruginosa. Indications Side effects a oO ‘Vo ~ miroor ed by Blactamases of many microbes, ey Lae = Scanned with CamScanneror ~~ ye Sy \ Ly \ TETRACYCLINS AND MACROLIDES per “4 we \ Tetracycines Macrotides Natural Semisy Semisynthetic Dew 1. Tetrocyeline ‘Mechanism of action cel he level ofthe ribo ‘Spectrum of activity respiratory act (srptoceccal tone= | 4 rei, communy-acqured preumonia. | A oping cough. diphtheria) a “4. Supernfetions Salley Age bere 1 Hypersen Pregnansy, cation 2 Pregnancy ( 3. Lactation (6:9) to tetracyclines neue, staphylococcus and anaer- ie 0 day (05 g daily during 3 days Ip). The bactenicidal concentration ‘STIs ~ sexually transmitted infections, H. pylori ~ Helicobacter pylori Scanned with CamScannerClasitication| ¥ generation Drugs 2. Cephalexin (Kefles) ‘Mechanism of action Speetram of perinfections caused by entero Tndieations i ie Enlerobacera.staphy- locoeci, Preumococeas and Peewdomonas Side effects ‘Allergic reactions; hematolog Conant] aear ND! 1. 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