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Lars Erik Olson, Ph.D.

Marquette University and Medical College of Wisconsin


Department of Biomedical Engineering, P.O. Box 1881,Milwaukee, WI 53201-1881
(414) 288-3529 lars.olson@marquette.edu

EDUCATION:

Ph.D. 1993 Biomedical Engineering, Vanderbilt University, Nashville, TN


Dissertation title: An Optical Multiple Indicator Dilution Method for
Measuring Lung Microvascular Permeability-Surface Area

M.S. 1989 Biomedical Engineering, Vanderbilt University, Nashville, TN


Thesis title: The Assessment of Lung Microvascular Permeability by Multiple
Indicator Dilution: the Use of 14C-1,4-Butanediol and 14C-Urea as Barrier-
Limited Tracers

B.S.E. 1987 Electrical Engineering, Tulane University, New Orleans, LA

HONORS:

Marquette University College of Engineering Outstanding Teacher Year Award, 1996, 2003.

Proctor and Gamble American Physiological Society Graduate Student Award, 1991.

Vanderbilt University Graduate Student Research Day Award (Science), 1989.

Harold Stirling Vanderbilt Scholar.

PROFESSIONAL EXPERIENCE:

2018 to Present Vice Chair for Academic Affairs, Department of Biomedical Engineering,
Marquette University and Medical College of Wisconsin, Milwaukee, WI.

2016 to 2018 Interim Joint Chair, Department of Biomedical Engineering, Marquette


University and Medical College of Wisconsin, Milwaukee, WI.

2016 to Present Founder and President, Cortina Medical Devices, LLC.

2016 to Present Co-Founder and President, Cortina Global Medical Fund.

2015 to Present Member, Core Revision Facilitation Group, Marquette University,


Milwaukee, WI.
2013 to 2016 Interim Chair, Department of Biomedical Engineering, Marquette University,
Milwaukee, WI.

2009 to Present Director, Human Powered Nebulizer Project, Marquette University,


Milwaukee, WI.

2000 to Present Associate Professor, Department of Biomedical Engineering, Marquette


University, Milwaukee, WI.

1993 to 2000 Assistant Professor, Department of Biomedical Engineering, Marquette


University, Milwaukee, WI.

1988 to 1993 Pre-doctoral Fellow, Department of Biomedical Engineering, Graduate


School, Vanderbilt University, Nashville, TN.

1987 to 1988 Graduate Research Assistant, Department of Electrical and Biomedical


Engineering, School of Engineering, Vanderbilt University, Nashville, TN.

1987 Graduate Teaching Assistant, Department of Electrical and Biomedical


Engineering, School of Engineering, Vanderbilt University, Nashville, TN

FIELDS OF SPECIALIZATION:

Global respiratory health and appropriate technologies, high performance computing, cardiovascular
and pulmonary physiology, endothelial cell biology, mathematical modeling, mass transport, fluid
mechanics, optical instrumentation.

SCHOLARLY WORKS:

Refereed Journal Publications

Olson, L.E., A. Pou, and T.R. Harris. Surface-area independent assessment of lung microvascular
permeability using an amphipathic tracer. J. Appl. Physiol. 70:1085-1096, 1991.

Olson, L.E., D.J. Staton, M. Young, R.L. Galloway, and T.R. Harris. Sulfhemoglobinated
erythrocytes as an optical intravascular tracer in the lung. Annals of Biomed. Eng. 22:319-327, 1994.

Olson, L.E., T.R. Harris, A. Pou, M.N. Sayed-Ahmed, and R.L. Galloway., An optical multiple
indicator dilution technique to measure lung permeability-surface area: calibration and baseline
measurement. IEEE Trans. Biomed. Eng. 42:451-463, 1995.

Feiring, A.J., and L.E. Olson. Coronary stent and over-the-wire catheter exchange using standard
length guide wires; jet exchange "JEX" practice and theory. Catheterization and Cardiovascular
Diagnosis, 42:457-466, 1997.
Olson, L.E., M.P. Merker, R.D. Bongard, B.M. Brantmeier, S.H. Audi, J.H. Linehan, and C.A.
Dawson. Kinetics of plasma membrane electron transport in a pulmonary endothelial cell-column.
Annals of Biomed. Eng. 26:117-127, 1998.

Merker, M.P., L.E. Olson, R.D. Bongard, M.K. Patel, J.H. Linehan, and C.A. Dawson.
Ascorbate - mediated transplasma membrane electron transport in pulmonary arterial endothelial
cells. Am. J. Physiol. (Lung Cell Mol. Physiol.) 274:L685-L693, 1998.

DeMarino, S., L.E. Olson, N.A. Pou, S.U. Adams, and T.R. Harris. Optical and radioisotope
indicator dilution measurements in pulmonary edema. Annals of Biomed. Eng. 26: 417-430, 1998.

Olson, L.E., Merker, M.P., Patel, M.K., Bongard, R.D., Daum, J.D., Johns, R.A., and C.A. Dawson.
Cyanide increases reduction but decreases sequestration of methylene blue by endothelial cells.
Annals of Biomed. Eng. 28(1):85-93, 2000.

Audi, S.H., Olson, L.E., Bongard, R.D., Roerig, D.L., Schulte, M.L., and C.A. Dawson.
Toluidine blue O and methylene blue as endothelial redox probes in the intact lung. Am. J. Physiol.
(Heart Circ. Physiol) 278(1):H137-H150, 2000.

Dawson, C.A., Audi, S.H., Bongard, R.D., Okamato, Y., Olson, L.E., and M.P. Merker. Transport
and reaction at endothelial plasmalemma: Distinguishing intra- from extracellular events. Annals of
Biomed. Eng. 28:1010-1018, 2000.

Effros RM. Hogan G. Wahlen Hoagland K. Olson L. and W. Lin. Protection of the lungs from acid
during aspiration. American Journal of Medicine. 111 Suppl 8A:56S-59S, 2001.

LaDisa, J.F., Hettrick, D.A., Olson, L.E., Guler, I., Gross, E.R., Kress, T.T., Kersten, J.R., Warltier,
D.C., and P.S. Pagel. Stent implantation alters coronary artery hemodynamics and wall shear stress
during maximal vasodilation. J. Appl. Physiol. 93(6):1939-46, 2002.

Gross, E.R., LaDisa, J.F., Weihrauch D, Olson, L.E., Kress, T.T. Hettrick, D.A., Pagel, P.S.
Warltier, D.C. and J.R. Kersten. Reactive oxygen species modulate coronary wall shear stress and
endothelial function during hyperglycemia. Am. J. Physiol. (Heart Circ. Physiol.) 284(5):H1552-9,
2003.

LaDisa, J.F., Guler, I, Olson, L.E., Hettrick, D.A., Kersten, J.R., Warltier, D.C., and P.S. Pagel.
Three-dimensional computational fluid dynamics modeling of alterations in coronary wall shear
stress produced by stent implantation. Ann. Biomed. Eng. 31(8):972-80, 2003.

R.M. Effros, Olson, L.E., Lin, W., Audi, S.H., Hogan, R., Shaker, R., Hoagland, K., and B. Foss.
Resistance of the pulmonary epithelium to movement of buffer ions. Am J. Physiol. (Lung Cell Mol.
Physiol.) 285:L476-83, 2003.

Savla, U*., Olson, L.E. and C.M. Waters. Mathematical modeling of airway epithelial wound
closure during cyclic mechanical strain. J. Appl. Physiol. 96(2):566-74, 2004.

LaDisa, J.F., Olson, L.E., Guler, I., Hettrick, D.A., Audi, S.H., Kersten, J.R., Warltier, D.C., and
P.S. Pagel. Stent design properties and deployment ratio influences indexes of wall shear stress: a
three-dimensional computational fluid dynamics investigation with a normal artery. J. Appl.
Physiol. 97(1): 424-30, 2004.
LaDisa, J.F., Olson, L.E., Guler, I., Hettrick, D.A., Kersten, J.R., Warltier, D.C., and P.S. Pagel.
Circumferential stress evaluated using time-dependent 3D computational fluid dynamics models. J.
Appl. Physiol. 97(1):424-430, 2004.

Ladisa, J.F., Olson, L.E., Guler, I., Hettrick, D.A., Kersten, J.R., Warltier, D.C., Pagel, P.S.
Circumferential vascular deformation after stent implantation alters wall shear stress evaluated with
time-dependent 3D computational fluid dynamics models. J. Appl. Physiol. 98(3): 947-57, 2005.

Ladisa, J.F. Olson, L.E., Molthen, R.C., Hettrick, D.A., Pratt, P.F. Hardel, M.D., Kersten, J.R.,
Warltier, D.C., Pagel, P.S. Alterations in wall shear stress predict sites of neointimal hyperplasia
after stent implantation in rabbit iliac arteries. Am. J. Physiol. Heart Circ. Physiol. 288(5):H2465-
75, 2005.

Ladisa, J.F., Olson, L.E., Ropella, K.M., Molthen, R.C., Haworth S.T., Kersten, J.R., Warltier,
D.C., Pagel, P.S. Microfocal X-Ray computed tomography post-processing operations for
optimizing reconstruction volumes of stented arteries during 3D computational fluid dynamics
modeling. Comput. Methods Programs Biomed. 79(2):121-134, 2005.

LaDisa JF Jr. Olson LE. Hettrick DA. Warltier DC. Kersten JR. Pagel PS. Axial stent strut angle
influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics
models of stent foreshortening. Biomedical Engineering Online. 4:59, 2005.

LaDisa JF Jr. Olson LE. Douglas HA. Warltier DC. Kersten JR. Pagel PS. Alterations in regional
vascular geometry produced by theoretical stent implantation influence distributions of wall shear
stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling.
Biomedical Engineering Online. 5:40, 2006.

Kranzer K., Olson, L., van Schaik, N., Raditlhalo, E., Hudson, E., Panigrahi, P., Bekker L.G.,
Quality of induced sputum using a human-powered nebulizer in a mobile human immunodeficiency
virus testing service in South Africa. Int J Tuberc Lung Dis. Aug: 15(8), 1077-81, August 2011.

Hallberg C.J., Lysaught M.T., Najarro R.A., Cea Gil F., Villatoro C., Diaz de Uriarte A.C., Olson
L.E., Treatment of asthma exacerbations with the human powered nebulizer: a randomized clinical
trial. Nature: Primary Care Respiratory Journal. 14:14016, 2014.

Hallberg C.J., Lysaught MT, Zmudka CE, Kopesky WK, Olson LE, Characterization of a human
powered nebulizer compressor for resource poor settings. Biomedical Engineering Online, 13:77,
2014.

Goulet, B., B. Mayer, and L.E. Olson. A comparative life cycle assessment between a metered dose
inhaler and electric nebulizer. Sustainabilty 9(10):1725 DOI: 10.3390/su9101725, 2017.

Book Chapter

Dawson, C.A., R.D. Bongard, D.L. Roerig, M.P. Merker, Y. Okamoto, S.H. Audi, L.E. Olson, G.S.
Krenz, and J. H. Linehan. Pulmonary Endothelial Surface Reductase Kinetics. Whole Organ
Approaches to Cellular Metabolism, Permeation, Cellular Uptake, and Product Formation.
J.B. Bassingthwaighte, C.A. Goresky and J. H. Linehan, Eds. New York, Springer-Verlag, 1998.
Government Report

Olson, L.E., C. Villatoro, C. Santin. Estudio sobre: Eficacia del Nebulizador Manual en la práctica
de los Ecos Familiar en el Oriente de El Salvador: la atención de salud y el ahorro de costos. Report
to the Ministry of Health of El Salvador, April 2015.

Invited Paper

Olson, L.E., R.D. Bongard, M.P. Merker, J.H. Linehan, and C.A. Dawson. Endothelial transplasma
electron transport. Annals of Biomed. Eng. 25:S-19, 1997.

Refereed Conference Proceedings

Olson, L.E., Galloway, R.L., Harris, T.R. Real-time assessment of lung microvascular permeability:
Use of a CO2 laser aids measurement of 1,2-propanediol concentration. Proc. IEEE/EMBS
13(1):281-2, 1991.

Olson, L.E., and Goldberg, J.R., International Service Learning Senior Design Projects: Human
Power and Medical Devices., Proceedings of FIE, F4B, 2007.

Olson, L.E., Glucksberg, M.R., Malkin, R.A., and Poluta, M. Special Session-Biomedical
Engineering Ethics and Standards in the Developing World. FIE Conference, 2007.

Herzfeld, D.J., Olson, L.E., and Struble, C.A. Pools of Virtual Boxes: Building Campus Grids with
Virtual Machines, Proceedings of the ACM VTDC, June 2010.

Conference Sessions Organized and Presented

Olson L.E., Session on International Service Learning, BMES annual meeting, 2006. Presented
“Service learning solutions for appropriate respiratory technology in Central America.”

Olson, L.E., Glucksberg, M.R., Malkin, R.A., and Poluta, M. Special Session-Biomedical
Engineering Ethics and Standards in the Developing World. FIE Conference, 2007.

Olson, L.E., Founding Chair of Southeast Wisconsin High Performance Computing Consortium
(SeWHiP), Data Symposium, 2012.

Invited Lectures
Olson, L.E. Endothelial transplasma membrane electron transport: measurement and modeling.
National Simulation Resource on Mathematical Modeling Symposium, 1997.

Olson, L.E. "Optical Probes of Vascular Anti-Oxidant Mechanisms" Northwestern University


Biomedical Engineering Departmental Seminar, February 13, 1998.

Olson, L.E. "Bioreactor Studies and Vascular Anti-Oxidant Mechanisms" Pennsylvania State
University Biomedical Engineering Departmental Seminar, November 11, 1999.

Olson, L.E. “A better method for Cryopreserving Cells: Case Study of Erythrocytes” Medical
College of Wisconsin, September 26, 2002.

Olson, L.E., M.T. Lysaught, C.J. Hallberg, C. Villatoro. "The Human Powered Nebulizer."
IMECHE Appropriate Healthcare Technologies Seminar, London, September 18, 2013.

Conference Presentations

Harris, T.R., Olson, L.E., Pou, A. Lipid Solubility increases the sensitivity of indicators for
endothelial damage in the lung. Proceedings of the World Congress on Medical Physics and
Biomedical Engineering 33(1):351, San Antonio, TX, 1988.

Olson, L.E., Pou, A., Harris, T.R. Measurements of amphipathic and hydrophilic indicator-dilution
tracers in the lung provide a surface area independent assessment of permeability changes. FASEB J.
3:A1140, New Orleans, LA, 1989.

Olson, L.E., Pou, A., Harris, T.R. Evidence for the validity of 14C-1,4-butanediol (B) as a barrier-
limited, multiple indicator dilution (MID) tracer in the lung. FASEB J. 4:A1181, Washington, DC,
1990.

Olson, L.E., Galloway, R.L., Pou, A., Harris, T.R. Optical measurements in whole blood of tracers
for lung microvascular permeability. FASEB J. 5:A754, Atlanta, GA, 1991.

Olson, L.E., Pou, A., Syed - Ahmed, M.N., Galloway, R.L., Harris, T.R. On-line, optical
measurement of lung permeability surface area (PS) is sensitive to hypoxia and alloxan injury.
FASEB J. 7(3):A2924, New Orleans, LA, 1993.

Olson, L.E., R.D.Bongard, C.A. Dawson, and J.H. Linehan. On-Line detection of reduction and
sequestration of thiazine dyes by the lung. FASEB J. 8:A916, Anaheim, CA, 1994
Krenz, G.S., C.A. Dawson, J.H. Linehan, R.D. Bongard, M.P. Merker, and L.E. Olson. A simple
model of methylene blue reduction in the lung. Annals of Biomed. Eng. 22:44, Tempe, AZ, 1994.

Olson, L.E., M.P. Merker, R.D. Bongard, J.H. Linehan, and C.A. Dawson. Effect of hypoxia and
potassium ferricyanide on thiazine dye reduction and uptake in a cell-column model of the
pulmonary microvasculature. Annals of Biomed. Eng. 23:S-12, Boston, MA, 1995.

Olson, L.E., M.P. Merker, J.H. Linehan, and C.A. Dawson. Effect of flow on thiazine dye reduction
and uptake in a cell-column model of the pulmonary microvasculature. FASEB J. 10:A719, Atlanta,
GA, 1995.
Olson, L.E., R.D. Bongard, S.H. Audi, D.L. Roerig, J.H. Linehan, and C.A. Dawson. Plasma protein
binding and Toluidine Blue O (TBO) reduction in the pulmonary circulation. FASEB J. 11:A100,
University Park, PA, 1996.

Olson, L.E., R.D. Bongard, M.P. Merker, S.H. Audi, M.L. Schulte, J.H. Linehan and C.A. Dawson.
Comparison of transplasma membrane electron transport by pulmonary endothelial cells in situ and
in cell culture. Annals of Biomed. Eng. 24:S-27, University Park, PA, 1996.

Olson, L.E. and A.J. Feiring. Analysis of dynamics of a novel technique for over-the-wire balloon
catheter exchange during stent deployment. Annals of Biomed. Eng. 24:S-27, University Park, PA,
1996.

Dembowski, E.T.(UG), L.E. Olson, G.S. Krenz, S.H. Audi, C.A. Dawson, and J.H. Linehan. Effect
of on-line sampling and dye properties on optical measurements in a flow-through endothelial cell
system. Annals of Biomed. Eng. 24:S-54, University Park, PA, 1996.

Olson, L.E., R.D. Bongard, M.P. Merker, M.K. Patel*, J.H. Linehan, and C.A. Dawson. Endothelial
redox status and transplasma membrane electron transport. FASEB J. 11:A136, New Orleans, LA,
1997.

Bongard, R.D., L.E. Olson, M.K. Patel*, J.H. Linehan, C.A. Dawson, and M.P. Merker.
Dehydroascorbate stimulates pulmonary arterial endothelial cell transplasma membrane electron
transport. FASEB J. 12:A182, San Francisco, CA, 1998.

Olson, L.E., R.D. Bongard, M.P. Merker, M.K. Patel*, J.H. Linehan, and C.A. Dawson. Effect of
cyanide on kinetics of extracellular reduction and intracellular reoxidation of Methylene Blue (MB)
by endothelium. FASEB J. 12:A182, San Francisco, CA, 1998.

Olson, L.E., Merker, M.P., Bongard, R.D., Linehan, J.H., and C.A. Dawson. Cell column studies of
endothelial transplasma membrane electron transport (ETMET) mechanisms. Annals of Biomed.
Eng. 26(S):S-51, 1998.

Vosniak, K.J., Olson, L.E., Clough, A.V., Linehan, J.H., and C.A. Dawson. Computational fluid
dynamics model study of transit time through arterial trees. Annals of Biomed. Eng. 26(S):S-65,
1998.

Olson, L.E., Audi, S.H., Lin, N., Lin, W., and C.A. Dawson. Adaptation to hyperoxia results in
pulmonary sequestration of toluidine blue O (TBO+). FASEB J. 13:A184, 1999.

Clough, A.V., Haworth, S.T., Vosniak, K.J.*, Dawson, C.A., and L.E. Olson. Transit time through
the pulmonary arterial tree: Experimental and modeling observations. FASEB J. 13:A428, 1999.

Olson, L.E. Yakubovich, O., Clough, A.V., and C.A. Dawson. A fast algorithm for predicting
transit times through arterial trees. FASEB J. 14:A168, 2000.

Olson, L.E., Effros, R.M., Hogan, G., and W. Lin. Alveolar pH changes and trans-alveolar
transport.
Annals of Biomed. Eng. 28(S):S-48, 2000.
Gross, E.R., Olson, L.E., Weihrauch, D., Kersten, J.R., Hettrick, D.A., Pagel, P.S., and D.C.
Warltier. Acute hyperglycemia alters shear and oxidant stress in coronary arteries in vivo. Annals of
Biomed. Eng. 28(S):S-63, 2000.

LaDisa, J.F., Olson, L.E., DiCaprio, F., Guler, I., and D.C. Warltier. In vivo measurement and fluid
dynamics modeling of hemodynamic changes produced by coronary stenting. FASEB J. 2001.

LaDisa, J.F., Olson, L.E., Hettrick, D.A., Guler, I., DiCaprio, F., Pagel, P.S., Kersten, J.R., and D.C.
Warltier. Computational fluid dynamics modeling of hemodynamic changes caused by coronary
stenting in vivo. Ann. Biomed. Eng., 2001.

LaDisa, J.F., Olson, L.E., Guler, I., Gross, E.R., Hettrick, D.A., Kersten, J.R., Warltier, D.C., and
P.S. Pagel. Coronary stent implantation alters wall shear stress during maximal vasodilation. IEEE
Engineering in Medicine and Biology Proceedings v2 2002:1228-9, 2002.

Schedgick, D.J.*, Olson, L.E., Bigelow, L.K. and W.E. Brower. Cryopreservation of erythrocytes
without a cryoprotectant by rapid quenching and rewarming. Cryobiology, 2002.

LaDisa, J.F., Warltier, D.C., Olson, L.E., Kersten, J.R., and P.S. Pagel. Shear-modulated neointimal
hyperplasia after stent implantation. FASEB J. 2003.

Ladisa, J.F., Olson, L.E., Kersten, J.R., Warltier, D.C., and P.S. Pagel, Wall shear stress varies with
stent properties and correlates with sites of neointimal hyperplasia. Ann. Biomed. Eng., 2003.

Zitomer, D., Olson, L.E., Borg, J. International Service Learning at Marquette University. Role of
Engineering at Catholic Universities (RECU) Conference in Dayton, OH 2005.

Olson, L.E., LaDisa, J.F. A model of Shear-Dependent neointimal growth of stented vessels, Ann.
Biomed. Eng. 2007.

L.E. Olson. Human Powered Nebulizer is Equivalent to Commercial Nebulizer in rate of Liquid
delivery. BMES 2009

Olson LE, “The Human Powered Nebulizer in Developing World Applications,” Presentation at
Unite For Sight Conference, Yale University, April 2010

Olson LE, Zmudka CE, Hallberg CJ, Kopesky WK, Lysaught MT, Particle size measurements of the
human powered nebulizer, BMES 2012.

Research Projects Funding

Principal Investigator - Marquette Research Challenge Grant: "Analysis of Functional Brain


Magnetic Resonance Images using Fiber - optic Cortical Measurements", for $10,000 in 1994/95.

Co–Investigator (J.H. Linehan P.I.) – National Institutes of Health, Heart Lung and Blood Institute:
“Lung Metabolism of Vasoactive Hormones”, for $132,062 per year from 1995 – 1999.
Role: Develop mathematical models and numerical solution methods for identification of parameters
of endothelial function. Develop new optical methods for investigation of lung metabolism.
Principal Investigator - Anthony J. and Rose E. Bagozzi Medical Research Fellowship: “Equipment
and Supplies for Endothelial Cell Investigation”, for $9,300 from 1996 – 1999.

Co–Investigator (. J.H. Linehan, P.I.) - Ralph and Marion Falk Medical Research Trust:
“Primary Pulmonary Hypertension”, for $360,000 from 1997 – 1998.
Role: Develop probes of endothelial function, which influence the pulmonary hypertension. Use
computation fluid mechanics to study mechanical aspects of pulmonary.

Functional Imaging Faculty-Whitaker Foundation Special Opportunity Award: “Ph.D. Degree


Program in Functional Imaging”, for $331,000 per year from 1996-1999.
Role:Consultant—Participate in functional imaging training.

Principal Investigator-American Heart Association Beginning Grant-in-Aid: “Endothelial


Transplasma Membrane Electron Transport: Mechanisms and Roles in Intracellular Signaling” for
$69,992 from 1999-2001.

Principal Investigator-Scimed Life Systems Graduate Industrial Fellowship: “In vivo


Computational Fluid Dyanamics Modeling of Coronary Stent Mechanics and Dynamics” for
$39,910 from 2000-2002.

Investigator, NSF Grant, “Acquision of a Linux Cluster to Support College-wide Research and
Teaching Activities” 2006.

Principal Investigator, NCIIA Grant, "The Human Powered Nebulizer" for $45,000, from 2010-
2011.

Co-PI, NSF Grant, " MRI: Acquisition of a Parallel Computing Cluster and Storage for the
Marquette University Grid (MUGrid)", for $560,000 from 2009-2011.

Principal Investigator, CTSI Grant, “Toward a bioinformatics and bioengineering core for
Southeastern Wisconsin: Internship Program.” $50,000, 2015-2016.

Principal Investigator, Seed Enterprise Fund Grant, Marquette University and WEDC, “Human
Powered Nebulizer” for $50,000, 2017.

TEACHING AND MENTORING ACTIVITIES:

Courses Taught

BIEN 1120 Introduction to Computing for Biomedical Engineers (created)


BIEN 2300 Biomedical Circuits and Electronics (co-created)
BIEN 3200 Computer Applications in Biomedical Engineering
BIEN 4320 Biomedical Instrumentation Design
BIEN 4400 Transport Phenomena
BIEN 4731 High Performance and Parallel Computing
BIEN 6400 Biofluid Mechanics
BIEN 6410 Biological Mass Transfer
BIEN 6710 Cellular and Molecular Bioengineering
BIEN 6953 Seminar in Biomedical Engineering

Graduate Student Interaction

Thesis Advisor:

Student Involvement Semesters

Sejal Patel M.S. Thesis Advisor FA96 - FA98


Title: A Model of Pulmonary Endothelial Transplasma Membrane
Electron Transport: Inclusion of Plasma-Protein Binding.

Meha Patel M.S. Thesis Advisor FA96 – SP99


Title: The Effect of Cyanide on Methylene Blue Reduction and
Uptake in Cell Columns

Kenneth Vosniak M.S. Thesis Advisor SP98 – FA99


Title: Computational Fluid Dynamic Studies of Transit Time
Through Arterial Bifurcations

John Ladisa M.S. Thesis Advisor SP00-SU01


Title: Computational Fluid Dynamic Study of Coronary Arterial Stents

John LaDisa Ph.D. Dissertation Advisor FA01-SP04


Title: Computational Fluid Dynamics Estimations of Wall Shear Stress
Alterations Influencing Neointimal Hyperplasia After Stent Implantation.

Jason Clyne M.S. Thesis Advisor FA03-F05


Distensibility of Coronary and Intestine Arterioles in Relation to Heart
Disease.

Ankit Shah M.S. Thesis Advisor SP04-F05


Development of an In Vitro Vascular Flow Model to Determine the
Pharmacokinetics of Locally Delivered Therapeutics: A Comparison of
Drug Physiochemical Properties and Modes of Delivery.

Richard Schroeder M.S. Thesis Advisor SP15-Present

Thesis Committees:

Student Involvement Semesters

Amir Al-Tinawi Ph.D. Committee Member 1993 – 1994


Junghwa Hong Ph.D. Committee Member 1994 – 1996
Mary Spilker M.S. Committee Member 1995 – 1998
Todd Schmeling M.S. Committee Member 1998 – 1998
Jason Daum M.S. Committee Member 1998 – 1998
Ushma Savla Northwestern University, Ph.D.
Committee Member 2003 - 2004
David Schedgick Ph.D. Committee Member 2001 - 2004
Michael Stineman M.S. Committee Member 2004 - 2005
Moses Darpoalarr Ph.D. Committee Member 2005 - 2006.
Andrew Williams M.S. Committee Member 2008 - 2008.

David Quam M.S. Committee Member 2010-2012.


Franco Rupcich Ph.D. Committee Member 2010-2013.
Kwon Sung M.S. Commitee Member 2011-2013.
Tamara Cohen Ph.D. Committee Member 2013-Present.
Ben Dickerhoff Ph.D. Committee Member 2016-Present

Advisor for Senior Design Projects:

2017-2018 Low-Cost Ventilator


2017-2018 Electronic Medical Record
2016-2017 Low-Cost Ventilator
2016-2017 Low-Cost Patient and Healthcare Record System
2015-2016 Low-Cost Suction Device for Lower Respiratory Infections
2014-2015 Human Powered Oxygen Concentrator.
2013-2014 Human Powered Oxygen Concentrator: bicycle-based design
2012-2013 Human Powered Nebulizer: Manufacturable design
2011-2012 Human Powered Nebulizer: hand-cranked design
2010-2011 Human Powered Nebulizer: bicycle-based design; treadle design
2009-2010 Human Powered Nebulizer: bicycle-based design
2008-2009 Human transporter for Africa
2008-2009 Hydropur: Human powered UV water sanitizer for medical applications
2007-2008 Bicycle powered AC electrical storage supply for medical applications
2007-2008 Step powered nebulizer for Latin America
2006-2007 Mechanical nebulizer for Latin America
2005-2006 Low-cost mechanical nebulizer for Central America
2004-2005 Glucose meter for Guatemala
2003-2004 Low-cost wheelchair for Central America.

SERVICE ACTIVITIES:

Marquette University Service

Biomedical Engineering Department Graduate Committee, 1993-1998


Mechanical Engineering Curriculum Committee, Fluid Mechanics Area, 1994-present
Instructor for the Marquette University Young Scholars Program, 1994.
College of Engineering Task Force on Computer Aided Design, 1995-present
Advisor for the Biomedical Engineering Society (BMES) Marquette University Graduate Student
Chapter, 1995-present
Engineering College Computer Resources Committee, 1995
Biomedical Engineering Department Undergraduate Committee, 1998-present
Chair, Biomedical Engineering Department Undergraduate Committee 2000-2004
Faculty Advisor, Student Chapter of BMES 2000-Present
Member, Health Environment and Infrastructure in Latin America.
Co-director, 2004 Spring International Service Learning Guatemala Trip.
Director, 2005 Spring International Service Learning Guatemala Trip.
Member, University Technology Committee, 2011-2013.
Member, Core Curriculum Review Committee, 2013-present.
Member, Milwaukee Global Health Consortium 2014-present.

Professional Service

1997 Served on National BMES Student Awards Committee


1996 Organizer/Chair of session of annual National BMES meeting.
2005 Organizer/Chair of session of annual National BMES meeting.
2006 Organizer/Chair of session of annual FIE meeting.
2010 EXCEDE Campus Champion.
2010 Founder, Southeast High Performance Computing Consortium (SeWHiP)

Professional Societies

Biomedical Engineering Society.


American Physiological Society.
Sigma Xi.
Alpha Sigma Nu.

Other Scholarly Activities

Reviewer, Journal of Applied Physiology


Reviewer, Annals of Biomedical Engineering
Reviewer, Biochimica et Biophysica Acta
Reviewer, Journal of Biomechanical Engineering.
Reviewer, Journal of Biomechanics.

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