Universidade do Porto

Faculdade de Engenharia da Universidade do Porto

Instituto de Ciencias Biomedicas Abel Salazar da Universidade do Porto

Final Report of Experimental Classes

Molecular Biointerfaces
Bachelor in Bioengineering

Ana Benedita Borges de Correia de Oliveira up201904820 Date: 24 December 2022

Guilherme Faria Dias up202204112

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Introduction
Polycaprolactone (PCL) is a biodegradable and
biocompatible polymer that has gained increasing
importance for various biomedical applications, such
as drug delivery, tissue engineering, and wound
dressings. In this study, PCL films were fabricated
using the solvent casting method and modified with a
surface hydrolysis with a solution of sodium
hydroxide. The wettability and surface roughness
(SEM) of the films were evaluated to assess their
potential as biomaterials. The biological response of
the films was also studied in vitro using cell culture
techniques. This report presents the results of these
studies and discuss their implications for the use of
PCL films in biomedical applications.

Result and Discussion

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