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Description | 1.| Putocotds (Histamine, Sevstonin, Prostanlandd n) J 2-|Deugs acting on RTS (cough, acthena Race | cata Rutoeotals (Grek vol) Date 6*-Feb- 2022 I= Akos on Pate 2S colds " SS -7 Endogenoit’ substances produce Lota and ack locally. - — Endon Ns > oe Bt poy [»%¥in the bed coe es: ie coe 2 Defercting Son the chenttry | | aoe sPircing AP (Hifkarine, Senkontne) ¥ ect ond : | 4 4 amive acto . ete es Ae (Brads tinin) = 7 > More th Ino aetols. | gy fetes jo Lipid derived AX 2glarctine) Base prrdocec) a ony B=, Others (Gastin, es) — Z i | Masel Putacoidls _& Newtotra nsmifttes ® Predutadtn AS No thempeutt ue becouse te fas Plecte on =o ee | Desipheral smecth muscles % _—— L NO availate dsuq tm makel 5 » Rotitis. 5 sagt ne: duet Milorimahin in Bhevere fe gir ee and eee due % polls n i Date Fate: 7 > Store tm vestlls. is eats Teer cost = | r= . t stored It vapfo ne Troctvale eee pre ta Sy Utne Test _ ac eines eased ene prsene. ey Briiclgzole cacti acial, (metabes e: |_ histamine the he erxiclase (Timid : Release: ? 4 on ve Oo oo > Chemica) release - i oatdne a, a ~ ” a | BECL sel — Ha Gs —> c AMP—> PK Pp Hin aalt Fc | Allergen enter tr booly —» Th -2 ? ~produce —. £) -» veaspteys ae on masteelis anol baso Cy = Pere mest cell 40 whenever allergen come arnt oa = a e. 2 | — | co 1 clefense_mmechansina starts | = aoe te *BOr/o Yerorters cue GPCRS- = 1 PLC > Phospheltelss ad 2 DAG cy Ames J 5; °@ | univers st Pra —9 relavont ae C . | A miep a by Got t+ Cal mocuudlfn 2) ae . ~_MLCP. | MLEK 32 | 3 wortrockin | Tropontalremore) + | Acte[Myesin —> 8 contraction eros b: J 9 ) > eo CAMP Ly (Untversa) velaxant =z olen We ore Trthis core to atom far os CO Saw es > Ie, 2 Adclenylauyclase carpet = a Ge > Prarsrracolerteal Ackion af Histamtne fous Systems (Hy, $3) as a nemotransmtttec +sWep , Arpelitet\ford trtake) » Sew autal] ‘ saa tamtnic Trans rafsion REUSE - iy Testa s eno G | prions a Hr muy fo voneorboey |» — Sc co Be tute Bid alot + i ons | _ sz Sen ynunt y 2 ¢ a ( Foie ntl >ferBo aborption : erent (Patiotad > EnBinsic eckon | rete x é Reema ote Pasta, “ Ls esha lamine 3 eee eusedtn Piel [+ Mlornaytic. caer anemia Centhy co Kal. Tadics. jaa Ee oa fren = widely distibuted tn fad intake fron 1 P Snlestine Fesmur Sulplate | exsOU, ate { Gbtek _ Spithdlsinn Es Smtr cog 22 g pee, 5 ri | then (U5 Heme eo wo > fermuge | eric Trons|erin Crore Seat egg stn eideey 3 Ferric 3+ | 9 Toxicity: pee | ot =o aaa Crave iS aie: aah) 4 edeme S-odsorart | oven —> hemoe Freomectosin Fahd bat. Prittdate cle.tvo amine bind Ae tron ond dco mst ely Seger te epee By ouged pee ar, —auphapaad oqus aprrctlpe SE YES wep 49

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