The Transdermal route

Transdermal drug administration refers to substances that are absorbed through the
skin, in its simplest term, a drug is placed on top of the skin, where it is absorbed into
the bloodstream.
Some of the most common examples of these are nicotine patches or patches that
contain painkillers, such as prescription opioids. Transdermal patches enable slower
drug delivery over time to control chronic pain also it is used to treat various conditions
such as hypertension & motion sickness. It can also refer to implants placed just under
the top layers of skin or simple creams rubbed onto the skin.

Disadvantages of transdermal route of drug administration

 Potential skin sensitization or irritation.
 Daily dose of more than 10mg is not possible.
 Patch may fall off.
Advantages of transdermal route of drug administration
 Bypasses the first pass effect.
 Convenient & painless
 Self-medication is possible.