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Research Snapshot Theater: Quality/Resuscitation/Pulmonary

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A SURVEY OF PHYSICIAN-PERCEIVED BARRI- TRANSIENT ISCHEMIC ATTACK SECOND-
ERS TO TARGETED TEMPERATURE MANAGE- ARY TO AIR EMBOLISM FROM RIGHT RADIAL
MENT CATHETER
Selina Sutchu1, Dacia Ticas1, Tierra Smith1, John Dollerschell1, Caleb Emma Nash1, Brooke Veer-Sundermeier2, James Sullivan2, Daniel
Harrell1, Madelaine Mills1, Shreya Patel1, Torben Becker1 Johnson3

Introduction/Hypothesis: Neurologic prognosis following car- Introduction: Invasive blood pressure monitoring via an arte-
diac arrest remains poor. In 2015, the American Heart Associa- rial line is frequently performed in the ICU for hemodynamic
tion updated their guideline that comatose adult patients with monitoring and frequent lab draws. Here we describe a previ-
return of spontaneous circulation after cardiac arrest should ously unreported complication of radial arterial air embolism
have targeted temperature management (TTM) for at least 24 resulting in transient ischemic attack.
hours. The aim of this study was to explore practice pattern Description: A 25 year-old man underwent aortic and mitral
and views of physicians within an academic medical center re- valve replacement with mechanical valves due to recurrent
garding TTM for patients resuscitated from cardiac arrest. bacterial endocarditis and was subsequently anticoagulated
Methods: We conducted an anonymous survey of physicians on a heparin infusion. On postoperative day 1, he remained
who make decisions about TTM initiation and continuation at intubated, on vasopressors, sedated and was able to move all
the University of Florida. The survey questions were developed extremities to command. Overnight the patient had an acute
following a literature review of guideline adherence research change in mental status, and the nurse practitioner and physi-
and refined during review by a multidisciplinary cardiac arrest cian were called to bedside. Per report, the nurse was attempting
research team. The survey was disseminated electronically with to flush a malfunctioning arterial line when the patient became
advertisement at educational conferences. unresponsive with bilateral nystagmus. The nurse practitioner
Results: The response rate was 64% (80/125). The respondents then noted that the tubing from the pressurized saline was dis-
were emergency physicians (34%), medical intensivists (30%), connected and now full of air. They suspected neurologic de-
cardiologists (24%), surgical and anesthesiology intensivists cline was related to air being pushed into the right radial artery.
(6%) and neurointensivists (5%). The majority of the respon- A code stroke was called and the patient was taken for head CT,
dents reported managing patients after cardiac arrest weekly where several small air emboli were found within the vascula-
to monthly (71%) and having personally initiated TTM for ture of the right hemisphere. The patient did begin moving his
a patient (75%). Almost one third of respondents (29%) had right side but was still unable to move the left. Arrangements
discontinued TTM orders prior to a full 24 hours of TTM. Rea- were made to undergo emergency hyperbaric oxygen (HBO)
sons of discontinuation included skepticism in the evidence of therapy, however the patient began improving so therapy was
cooling patients with non- shockable rhythms (24%), lack of held given the risks for critically ill patients. Within 8 hours the
consensus within and between departments (19%), lack of re- patient was fully neurologically intact.
sources (18%), concern for prolonging neuroprognostication Discussion: Air anywhere in the arterial tree is a severe risk for
(9%), fear of bleeding complications (5%), and difficulties with devastating embolism, and there is extensive literature describ-
the electronic health record (1%). ing this in cardiopulmonary bypass and ECMO cases. Distal
Conclusions: This study highlights the lack of consensus about arterial line cannulation is very safe by comparison, and in
TTM implementation at our large academic medical center. fact there are no reported cases involving distal arterial lines in
Discrepancies in reasons for guideline nonadherence were evi- humans, and only one report of using cows as a model for iat-
dent between departments. This study emphasizes the need for rogenic embolism. This patient’s outcome was likely due to his
more collaboration on initiating and continuing TTM in the youth and healthy collateral vasculature, as well as his short is-
post-arrest period. Future study will involve both local groups chemic time that likely spared the penumbra contributing to his
and national critical care organizations in overcoming barriers functional recovery. This case demonstrates that air embolism,
to best practices in post-cardiac arrest care. even from a distal arterial line, can cause devastating conse-
quences, and a high level of vigilance is required when manipu-
lating these common tools.

1
Omaha, NE, 2University of Nebraska Medical Center, Omaha, NE, 3University
University of Florida, Gainesville, FL
1
of Nebraska, Omaha

Critical Care Medicine • Volume 48 • Number 1 (Supplement) www.ccmjournal.org

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