Product highlights CAB-O-SIL M-SP fumed silica is an excipient of extremely hit suitable for use asa multi-functional additive in the pharma sutraceutical industries. CAB-O-SIL fumed silica is compatiblf pharmaceutical ingredients and can act.as a flow aid to red in tablet and capsule production including poor flow throug] active/inactive ingredient segregation, and tablet breakage d Purity thatis reutical and with many "© common Issues the hopper, luring compaction. Information on regulatory compliance may be found in the Pharma Grade Statement: CAB-O-SIL* M-SP & M-SDP Fumed Stica for Pharmaceutical Applications, available ch the Cabot website. Key applications + Pharmaceutical tabletsand capsules Performance features Flow aid CAB-O-SIL M-SP fumed slica's glidant and anti-static properties can reduce the friction and static dnargesin high speed tablet and capsule machines, The addition of CAB-O-SIL M-SP fumed silica can enable bettel spacing between the powder particles, reduce moisture bridging and reduce static charge, helping to improve flow 4nd prevent bridging in the hopper. Die filing aid {The abilty to produce uniform tablets is dependent on the powder mix feeding into the dies ina rep When the powder exhibits less than optimel flow due to clumping, bridging or static charge build up, tablets with non-uniform weight and active ingredient content. CAB-O-SiL M-SP fumed silica can Imps Broperties of the mixture and aid partice rearrangement within the die during the earlystages of die filing and! compression. pducible manner. Compaction aid CAG-O-SIL ML-SP fumed silica can also increase tablet hardness by faclitating particle flow and reardongement during the early stages of the compression process, which can increase the bonding strength between powder particles, {his can help prevent poor tablet strength and subsequent defects that arise like chipping, capping|amiretion and breaking.CAB-O-SIL® M-5P FUMED SILICA Wide eatelaar PROPERTY VALUE Surface area 200 m/e Tapped density <60 sil Dispersi Easily dispersed N/A ‘The data in thetableaboveare typical test values intended 2s guidance only, and arenot products pecifidstions, Product ‘specifications are available from your Cabot representative, Product form and logistics Product form: powder Regionalavailability: global + Bag packaging: 101b. bags For information on productspecificstorage conditions, please efer to the applicable Safety Data Sheet (S05) availab from your Cabot representative ar at cabotearp.com, ‘The CAB-O-SIL namels a registered trademark of Cabat Corporation, own nent Sour aman curome oor wstamick AS Seer aot fitetSpectyenmene Ghar com oe Seca hi ‘eit Seelam te Seine tae Oran 3 nese bosradsiemue a (aed as oer saat stot, eyotoscoxz itantotasieransrnjensnt Heh wes egner mobs ie eke enh i enon Anes ohana FRRSEAS Wf SE ESHA Oe et ra dew asap sda Stony ay dagen cnet week Pecoucr i ntaacun Pear Wee mee 2 SE moe ‘erect copenton CABOT® ssCABOT >» SAFETY DATA SHEET Regulation (EC) No 1907/2006 (REACH), Article 31 Revision date: 20-May-2015 According to Article 31 of the Regulation (EC) No 1907/2006 {REACH}, a Safety Data Sheet (SOS) must bd provided for hazardous substances or mixtures. This product does not meet the classification criteria of the Regulation (EC) No }272/2008 (cP) ‘Therefore such document is outside the scope of Article 31 of REACH and the requirements for content fr each section donot apply AHDENTIFIOATION Product Identifier TOF THE SUBSTANCE/BREPARATIONIAND OR TNECOMPA IDERTAKING 1 | Product code: MSP Product name: CAB-O-SIL @ Untreated Fumed Silica - Pharmaceutical Grade REACH registration number: 01-2119379499-15, ‘Synonyms: Untreated Fumed Silica, Silicon Dioxide, Synthetic Amorphous Silicp, Pyrogenic (Fume) Amorphous Silica, Colleidal Silicon Dioxide, Colloidal Anhydrous Sifca, Light Anhydrous Silicle Acid This SDSis valid for CAB-O-SIL® Untreated Fumed Silica: MSP, MSDP the following grades: 1.2. Relevant identified uses of the substance or mixture and uses advised against 42. Relevant identified uses of the substance ot mixture and uses advised against Recommended use: Multifunctional excipient for pharmaceutical solid, semi-solid, andiquid forms, Free flow agent, Anti-caking agent, Spray aid, Anti-blocking agent, Anti-settlibg agent, Thickening ‘agent, Stabilization agent, Carrier, Other Uses advised against: Not known as per REACH joint registration dossier. 13. Details of the supplier of the safety data sheet Cabot EMEA* Headquarters, CABOT SWITZERLAND GmbH Miihlentalstrasse 36 £8200 Schaffhausen Switzerland Tel: +42 (0) 52 630 3838 Fax: +41 (0) 52 630 3810 Cabot EMEA Business Service Center 101 Mukusalas Street Lv-1004 Riga Latvia Tel. #371 67050700 * Europe, Middle East and Africa Poge 1/13Product code: MSP Product name: CAB-O-SIL® Untreated Fumed —_Revisid Stlica - Pharmaceutical Grade date: 20-May-2025 E-mail address: SDS@cabotcorp.com 1.4, Emergency telephone number Emergency Telephone Number; _24H/74 service Germany: CHEMTREC 0800-181-7059 UK: CHEMTREC: (+44)-870-8200418 US: CHEMTREC: +1-703-527-3887 or 1-800-424-9300 CHEMTREC China: 4002-204937 {International CHEMTREC: +1 703-741-5970 or +1-703-527-3887 2.2. Classification of the substance or mixture 2:1. Classification of the substance or mixture Dene hazardous substance according to Regulation (EC) 1272/2008 (CLP, its various amendments and ad}ptations and Directive 67/548/EEC, Label Elements Pictogram: None Signal Word: None Hazard statemen None Precautionary statements: None 2.3. Other Hazards None. Principle Routes of Exposure: Skin Contact, Eye contact Eye Contact: May cause mechanical iritation. Avoid contact with eyes, ‘Skin Contact: May cause mechanical irritation and skin drying. Avoid contact with sifn. No-cases of sensitization in humans have been reported, Inhalation: Dust may be Irritating to respiratory tract. Provide appropriate exhaust ventilation at ‘machinery and at places where dust can be generated, See also Sectio Ingestion: Adverse health effects are not expected. See Section 11, Page 2/13Product code: MSP Product name: CAB-O-SIL® Untreated Fumed Revisida date: 20-May-2015 ~ Pharmaceutical Grade Carcinogenicity: pa not contain ay substances greater than 0.3% sted by tad (Intemational Agency {for Research on Cancer), NTP (National Toxicology Program, OSHA (Occupational Safety and Health Administration}, ACGIH (American Conference for Gofernmental industri Hygienists) or EU (European Union). See also Section 11, ‘Target Organ Effects: Lungs, See Section 11 ions Aggravated by Asthma, Respiratory disorder Potential Environmental Effects: None known. See Section 12. 3.1 Substances a ei a = Synth 2sisas-4* | 112985-525 | >99.9 ‘ - lo1-2319379499-1¢ Amorphous, Pyrogenicsitica Other information: “Regulatory information is found under the general silica: CAS RN 7631-86-9, EINECS RN 231-545-4 The hyphen (-) means "not applicable" Rescription of first aid measures ‘Skin Contact Wash thoroughly with soap and water. Seek medical attention if syrfotoms develop. Eye contact Flush eyes immediately with large amounts of water for 15 minutes [seek medical attention if symptoms develop. Inhalation 'f cough, shortness of breath or other breathing problems occur, mope to fresh air. Seek medical attention if symptoms persist, f necessary, restore normal breathing through ‘standard first aid measures, Ingestion Do net induce vomiting. tf conscious, give several glasses of water. ever give anything by mouth to an unconscious person. 4.2. Most important symptoms and effects, both acute and delayed Symptoms: The most important known symptoms and effects are described in Sdction 2 and/or in Section 11, Page 3/13Product code: MSP Product name: CAB-O-sIL @ Untreated Fumed Silica - Pharmaceutical Grade 4.3. ndeation of any immediate medical attention and special treatment. needed Note to physicians: Treat symptomaticaly ene : Sane 5.1. Extinguishing media SulebleBainguising Media: Sicais non-combustible, therefore no extinguishing mela needs be dentine, Unsuitable Extinguishing Media: None. 5.2, Special hazards arising from the substance or mixture Specific hazards arising from the None, chemical: Hazardous combustion products: None. 5.3. Advice for firefighters Special protective equipment for Wear suitable protective equipment. in the event of fire, wear selffcontained breathing fire-fighters, apparatus. Risk of Dust Explosior Not Applicable. $.1. Personal precautions, protective equipment and emergency procedures Personal precautions: Avold dust formation. Ensure adequate ventilation. Use personal pr See also Section 8 tective equipment. For emergency responders: Use personal protection recommended in Section 8, 6.2. Environmental precautions Environmental Precautions: Contain spilled product on land, if possible, Local authorities should be advised if significant spillages cannot be contained, 6.3. Methods and material for containment and cleaning uy 8:3. Methods and material for containment and cleaning up_ ‘Methods for containment: Prevent further leakage or spillage if safe to do so, Methods for cleaning up: Fran UP Bromty by vacuum. Use of vacuum with high efficiency articulate air HEPA) filtration is recommended, Do not create a dust cloud by using a brush or compressed oie Pick up and transfer to properly labelled containers. See Section 13, 6.4, Reference to other sections Reference to other sections ‘See section 8 for more information. See section 13 for more informatfon. rae LOSES Page 4/13Product code: mis Product name: CAB-O-SIL® Untreated Fumed Revi Silica - Pharmaceutical Grade ZA, Precautions for safe handling 24, Precautions for safe handling Advice on safe hand! Avoid contact with skin and eyes. Avold dust formation, Do not ‘appropriate exhaust ventilation at machinery and at places wher Do not create a dust cloud by using a brush or compressed air. ‘Take precautionary measures against static discharges. ll metal bats of the mixing and cretnaa pe cauipment must be earthed/arounded. Ensure all equjoment is electrically General hygiene considerations: Handi accordance with good industrial hygiene and safety praftice, 172: Conditions for safe storage, including any incompatibities Storage Condition: Keep containers tightly closed in a dry and well-ventilated place with volatile chemicals as they may be adsorbed onto product, st. Conditions. Keep in properly labeled containers, ot store together e at ambient Incompatible materials: None known, 2.3. Specific end use(s) isk Management Measures (RMM) Per Article 14.4 ofthe REACH Regulation no exposure scenario hasbeen developed as the substance is not hazardous. ae |S SEsIEXPOSURE CONTROLS ES) 8:1 Control parameters Exposure guidelines: The table below is asummary, Please see the specific legsation tf complete information Amorphous Silica, The | regulatory Australia: mg/m", TWA, Respirable exposure limits are found under the Austria MAK 4 mg/m®, TWA, Inhalable fraction general silica, CAS RN 7631-86-9: Finland: Smg/m* Germany TRGS 900: 4mg/m?, TWA, Inhalable fraction India: 10 mg/m? TWA ireland 244 me/m?, TWA, Respirable dust Norway: 1S mg/m! TWA, Resptable dust Switzerland: ‘mes, TWA UK WEL: ‘6 mg/m’, TWA, inhalable fraction 2.4 mg/m, TWA, Respirable fraction US OSHA pet: mel (sa FR2702) Poge 5/13Product code: MSP Product name: CAB-O-SIL® Untreated Furned —_Revisidn date: Silica - Pharmaceutical Grade Dust, or Particulates Not Otherwise Gelgium: 10 mg/m, TWA, Inhalable Specified: 3 mg/m? TWA, Respirable China: 8 mg/m? TWA, 10 mg/m’, STEL France: 10 mg/m’, TWA Inhalable dust Sme/m?, TWA Respirable dust Italy: 10 mg/m? TWA, inhalable 3 mg/in®, TWA, Respirable Malaysia: 10 mg/m?, TWA, inhalable 3 mg/m?, TWA, Respirable Spain: 10 mg/m*, VLA, inhalable 3 mg/m?, VIA, Respirable US ACGIH PNos: 10 mg/m*, TWA, Inhalable 3 ma/m?, TWA, Resplrable US OSHA PEL: 15 mg/m, TWA, Total dust Simg/m®, TWA, Respirable Nore: In its facilities globally, Cabot Corporation manages TWA, Inhalable fraction ilica to the Germany TRGS 900 occupational exposurd limit of 4 mg/m’, {Wake MaximateArbetsplatzkonsentratin (Maximum Workplace Cancentraion) PEL: Permisiblo Emosure Umit NOS: Particlat Not Otherwise Specified STEL: Short Term Exposure Umit. ‘TAGS: Tehnische Regeln fr Gafahrstofie (Technical Rule for Hezardous Materials) ‘TWA: Time Weighted Average ‘US ACGIt Unite states American Conference of Governmental Industri Hygienists US Osta: Untea States Cccupational Safety ard Health Administration VLA: Valor Lite Ambientales (Environmental nit Val) WEL: Workplace Exposure init Derived No Effect Level (ONEL}: As required under the EU Registration, Evaluation and Authorizatior of Chemicals (REACH) Regulation, the Synthetic Amorphous Sillea REACH Consorthum (of whiich Cabot Corporation is a member) developed a Derived No Effect Level (ONE) for synthetic ‘Amorphous Sica of 4 mg/m? inhalable (Germany TRGS 900 occupatbynal exposure limit). Predicted No Effect Concentration Not Applicable, {enec) Exposure controls Engineering Controls: Ensure adequate ventilation to maintain exposures below occupatiofal limits. Provide appropriate local exhaust ventilation at machinery and at places whefe dust can be generated. Personal protective equipment [PPE] Page 6/13Product code: MSP Product name: CAB-O-SIL.® Untreated Fumed _Revisidn date: 20-May-2015 Silica - Pharmaceutical Grade Respiratory Protection: Approved respirator may be necessary if local exhaust ventilatiod Is not adequate. Hand Protection: Wear protective gloves to prevent skin drying, Use protective baifier cream before ‘handling the product. Wash hands and other exposed skin with Eye/tace Protection: ‘Wear eye/tace protection. Wear safety glasses with side shields (br goggles). ‘Skin and Body Protection: Wear suitable protective clothing. Wash clothing daily. Work clothing should not be allowed out of the workplace, Other: Handle in accordance with good industrial hygiene and safety praptice. Emergency eyewash and safety shower should be located nearby. Environmental exposure controls: In accordance witha focal legislation and permit requirements a applicable for dusts. ES HiVSIGAUAiD CHE MICAU PROPERTIES IE e ‘24. Information on basic physical and chemical properties Physical State: solid Odor: None Appearanc Powder Odor threshold: Not Appfcable Color: White Property. Values Remarks © Method ple 36-45 Inhouse testing Melting point/treezing point: 1700 °c NIOSH Packet Guide to Chemical Hazard Bolling point / bolting range: 2230 °C NIOSH Pocket Guide to Chemical Hazard! Evaporation Rate: Not Applicable Vapor pressur ‘Not Applicable Vapor Density: Not Applicable Density: 22 elem @20°C Butk Density: 30-150 ka/m? DIN/isO 787-11, SpecificGravityat20° 2.2 Water solubility: Slightly soluble ‘According to OECD 105 Solubility(es No information available Part Not Applicable Decompasition temperature: Not Applicable cosity: Not Applicable Kinematic viscosity: Not Applicable Not Applicable No oxidizing properties ‘Not Applicable VOC content (3: Not Applicable % Volatile (by Volume): Not Applicable % Volatile by Weight}: Not Applicable Surface Tension: Not Applicabie Explosive properties: Non-explosible Poge 7/13Product code: MSP Product name: CAB-O-SIL ® Untreated Fumed Silica - Pharmaceutical Gracie Flash Point: Not combustible Flammability (solid, gas): Not flammable. Product resists igni nnd does not promote fiame spread Flammability Limit in ai Not Applicable Explosion Limits in Air - Upper (g/m): Not Applicable Explosion Limits in Air - Lower (g/m): Not Applicable Autoignition Temperature: Not Applicable Minimum ignition Temperature: Not Applicable Minimum ignition Energy: Not Applicable Ignition Energy: Not Applicable Maximum Absolute Explosion Pressure: Not Applicable Maximum Rate of Pressure Rise: Not Applicable Burn Velocity: Not combustible Kst Value: Not Applicable Dust Explosion Classification: Not Applicable End point is isted "not applicable" due to the inherent properties of the substance "No information available” indicates testing has not been performed 9.2. Other information None See aoe ee 10.4, Reactivity Reactivity: Not reactive, Substance is an inert Inorganle solid. 10.2. Chemical stability Stability: ‘Stable under recommended handling and storage conditions. Explosion data Sensitivity to Mechanical impact: None + AOISTABIDVAND REACTIVE to Static Discharga: ‘This material is an inorganic dust and will not create nor support coifditions that would Fesult n a dust explosion or fire, Take precautionary measures agai static discharges ‘Avold dust formation, All metal parts of the mixing and processing euipment must be earthed/grounded., Ensure all equipment is electrically earthed/groupded before beginning transfer operations. 10.3. Possibility of hazardous reactions Hazardous polymerization: Hazardous polymerization does not occur. Sensiti Possibility of hazardous reactions: None under normal processing. ‘None known, Page 8/13Product code: MSP Product name: CAB-O-SIL® Untreated Fumed Revisidn date: 20-May-2015 Silica - Pharmaceutical Grade 10.8. Incompatible materials Incompatible mat 10.6. Hazardous decomposition products Hazardous decomposition products: None known None known _CLISTONICOLSGICATINFORMATIONS 11.1. Information on toxicological effects Acute toxicity Oral L050: Inhalation uso: Dermal L050: Skin corrosion/irritation: Serious eye damage/eye irritation: Sensitization: Mutagenicity: Carcinogenicity: Reproductive Toxicity: STOT- single exposur ‘STOT - repeated exposure: Aspiration Hazard: {DS0/oral/rat = > 5000 ma/kg, No deaths occurred and no signs of toxicity were seen ‘uring the observation periods after single oral administration of $ilca(OECD 402}, Due to the product's physical characteristics, no suitable testing ppcedure is available {050/dermal/rabbit = > 2000 mg/ke Very slight transient erythem in one animal. No signs of systemic or organ toxicity (OECD 402) Primary irtation index = 0/8 @ 24 hr, Not classified as an irritant (DECD 404). Braize score 2.0/110 @ 24 hr. Not clasifed as an irritant in rabbit ftudies (OECD 405). High dust concentrations may cause mechanical iritation, ‘No experimental animal data are available. No cases of sensitizatiop in humans have been reported. Not mutagenic in Ames test. Negative in the unscheduled DNA synthesis assay, Negative in the chromosome aberration test in Chinese hamster ovary (CHO|cels No evidence of carcinogenicity was observed in muitiple animal s repeated oral or inhalation exposure to amorphous silica. Similarly ‘show no evidence of carcinogenicity in workers who manufacture a ies following epidemiology studies jorphous silica, 'No effects on reproductive organs or fetal development have been Jeported in animal toxicity studies. Based on available data, specific target organ tonicity is not expectef after single oral, single Inhalation, or single dermal exposure. Repeated dose toxicity: oral (rat), 2 weeks to 6 months, no significarfttreatmentrelated adverse effects at doses of up to 8% silica in the diet. Repeated dose toxicity: inhalation (rat), 13 weeks, Lowest Observedfitfect Level (L061) = 13 mg/m® based on mild reversible effects in the lungs, Repeated dose toxicity: inhalation (rat), 90 days, LOEL = effects in the lungs and effects in the nasal cavity. on reversible mg/m? bas Based on available data, a STOT-RE classification is not warranted, Based on industrial experience and available data, no aspiration hazafd is expected. Page 9/13Product code: MSP Product name: CAB-O-SIL® Untreated Fumed _Revisidn date: 20-May-2015 Silica - Pharmaceutical Grade Aquatic Toxicity Fish (Brachydanio rerio} LC5O (86 h): > 10,000 mg/l; (Method: OEfD 203). No acute toxicity to Daphnia with EL and Else ranging from >1000 to 10,004 ma/t (OECD 202), 12.2. Persistence and degradability. ‘The methods for determining biodegradability are not applicable to inorganic substances 12:3. Bioaccumulative potential Not expected due to physicochemical properties of the substance, 12.4, Mobility in soil Mobility: Not expected to migrate 12.5. Results of PBT and vPvB. assessment This substance is not considered to be persistent, bioaccumul persistent nor very bioaccurnulating (vPvB). ing nor toxic (PBT). This substance is not donsidered to be very ee Disclaimer: Information in this section pertains to the product as shipped in its intended composition as dbscribed in Section 3 Of this MSDS. Contamination or processing may change waste characteristics and requirements. Regulatid ns may also apply to empty containers, liners or rinsate. State/provincial and local regulations may be different from federal rdgutations, Not Applicable Disposal should be in accordance with applicable regional, national regulations, ind local aws and FORMATION por 14.1 UN/D no Not regulated 14.2 Proper Shipping Name Not regulated Page 10/13Product code: MSP Productname: CAB-O-SIL® Untreated Fumed —_Revisifn date: 20-May-2015 Silica - Pharmaceutical Grade 14.3 Hazard Class Not regulated 144 Packing group Not regulated mos 14.1 UN/IDno Not regulated 34.2 Proper Shipping Nome Not regulated 16.3 Hazard Gass Not regulated 344 Pocking group Not regulated RID 14.1 UN/ID n0 Not cegulated 44.2 Proper Shipping Name Not regulated 143 Hazard class Not regulated 14.4 Packing group Not reguiated ADR. 14.1 UN/ID no. Not regulated 14.2 Proper Shipping Name Not regulated 143 Hazard Class Not regulated 144 Packing group Not regulated IcAo fair 14.1 UN/IDno ‘Not regulated 14.2 Proper Shipping Name Not regulated 143 Hazard class Not regulated 144 Packing group Not regulated ara 14.1 UN/ID no Not regulated 142 Proper Shipping Name Not regulated 14.3 Hazard Class Not regulated 14.4 Packing group Not regulated ea she ass RECOATORVIINEORMATION “Regulotary information is found under the general silica: CAS RN 7631-86-9, EINECS RN 231-545-4, 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture European Union Indication of danger: Not a hazardous substance according to Regulation (EC) 1272/2008 (CLP), its varioug amendments and adaptations and Directive 67/548/EEC. National Regulations Germany Water hazard class (WGK): nwg {not water endangering) £849 (amorphohis silica, CASRN 7631-86-9) ‘Swiss Poison class: ~ (tested and found to be not toxic): G-8311 International Inventories Page 11/13Product code: MSP Product name: CAB-O-SiL® Untreated Fumed Revi in date: 20-May-2015 Silica - Pharmaceutical Grade TSCA - United States Toxic Substances Control Act Section 8(b) Inventory Complies DSL/NDSt.- Canadian Domestic Substances List/Non-Domestic Substances List Complies FINECS/ELINCS -Evropean Inventory of Existing Chemical Substances/European List of complies Notified Chemical Substances ENCS - Japan Existing and New Chemical Substances Complies ECSC - China Inventory of Existing Chemical Substances Complies ECL - Korean Existing and Evaluated Chemical Substances Complies PICCS - Philippines inventory of Chemicals and Chemical Substances Complies AICS - Australian Inventory of Chemical Substances Complies NzloC - New Zealand Inventory of Chemicals Complies TCSI- Taiwan Chemical Substance Inventory Complies 15.2. Chemical safety assessment EU Chemical Safety Assessment: Per Article 14.4 ofthe REACH Regulation a Chemical Safety Assessmerf hasbeen carted out EU Exposure Scenarl ‘not hazardous. ‘er Article 14.4 of the REACH Regulation no exposure scenario has been develoed as the substance is 716 OTHERINFORVATIONS SS Pharmaceutical Use: See Section 1 Food Additive Us Not permitted References: NIOSH Pocket Guide to Chemical Hazards, September 2005. "Silica, amorphous". DHS (NICHI Publication No, 2005-149, National Technical information Service, Springfield, VA. p. 277 Gontacts: Cabot Corporation Cabot GmbH Cabot Carbon, td 157 Concord Road Kronensteasse 2 Sully Moors Road Billerica, Ma 01821 79618 Rheinfelden Sully, Vale of Glamorgn CF64 SRP UNITED STATES GERMANY Wales, UNITED KinecpM Tel: 1-878-663-3455 Tol (+49) 7623.707.0 Tel: (444) 1446.7369: Fax: 1-978-670-6955 Fax: (+49) 7623.707.530 Fax: (444) 1446.7372 Cabot Corporation Cabot BluestarLte, Cabot Corporation 700 € US. Highway 36 Xinghuo Industrial Garcen Tuscola, 61953-9643 Yongxiu County, Jiujiang City 330319 Midland, Mt 43640 UNITED sTaTES Jiangx! Province, CHINA UNITED STATES Telt-217-253-3370 Tel: (86-792) 3171616 Tel: 1-989-495-0030 Fax: 1-217-253-5530 Fax: (86-792) 3170320 Fax: 1-989-495-2139 Page 12/13,Product code: MSP Product name: CAB-O-SiL ® Untreated Fumed _Revisidn date: 20-May-2015 Silica - Pharmaceutical Grade ‘The information set forth is based on in implied, is intended. The information i responsibilty for use or reliance theret formation that Cabot Corporation believes and its English counterpart, the Englis tobe accurate. No Yarranty, expressed or is provided solely for your information and c consideration and CaHot assumes no legal ‘on. In the event of a discrepancy between the information on thd|non-English document h version shall supersede, Gabot Corporation - Safety, Health and Environmental Affairs 20-May-2015 © and "TM" indicate trademarks of the Cabot Corporation. End of Safety Data Sheet Page 13/13,