DEPARTMENT OF BIOTECHNOLOGY NAME : TOGA BRANDON REG NUMBER : C22151745G PROGRAM : BIOTECHNOLOGY ( BSBIO ) MODULE : MICROBIOLOGY(CUBIO103) LECTURER : MS. M CHIMHOWA ASSIGNMENT : 2 Assignment 2 1. The cell membrane consists of membrane proteins which enables it to undergo its functions. The cell membrane is composed of a lipid bilayer with transmembrane proteins such as globular proteins that run through both layers of the lipid bilayer. The trans/integral proteins help in the transportation of substances such as glucose in facilitated diffusion. The peripheral membrane proteins usually found on either surface of the lipid bilayer help in cell signal transduction that is function as receptors for peptide hormones. Membrane proteins act as junctions by linking intercellular components of the cell to extracellular ones. Glycoproteins with carbohydrate groups attached to them function as cell surface receptor sites. Glycoproteins keep cells moist and allow adhesion of molecules to take place. Some interior proteins such as spectrins and clathrins are situated structurally to support the plasma membrane. Some proteins are for production of enzymes to perform metabolic reactions in the cell membrane. Peripheral membrane proteins enable cell to cell recognition and also attachment of cytoskeleton and the extracellular matrix. Integral proteins allow both active and passive transport to occur enabling exchange of certain substances such as sodium ions across the plasma membrane. 2. The cell surface membrane has a unique structure which enables it to carry out its functions of the cell. The membrane is called the Fluid Mosaic Model because it is always in constant motion and fluid. The cell membrane has major components which include the phospholipid bilayer, the transmembrane proteins, peripheral membrane proteins and the cell surface receptors also known as surface markers. The peripheral membrane proteins are those attached to either surface of the bilayer. The phospholipid bilayer covers a larger surface area because it contains 2 layers of non- polar tails which point inward and the polar head which face the outside environment on the membrane surface. The lipid bilayer has hydrophilic heads which are water loving due to their polarity and hydrophobic tails (saturated or unsaturated) which are fat loving due to their long hydrocarbon chains. Bilayer is fluid since the interaction of the lipids and the outer aqueous surrounding keeps the lipids floating in the bilayer. The unsaturated hydrocarbon tails keep the more fluid. Cell membrane has cholesterol mostly found on areas with lots of unsaturated fats which helps in maintaining membrane fluidity by stabilizing the bilayer when it becomes less fluid and permeable. The cell membrane is selectively permeable due to hydrophobic interior hence regulates the entry and exit of molecules such as water, oxygen, and amino acids. The lipid bilayer consists of globular proteins which help in selective transportation of substances such as glucose through facilitated diffusion. The cell membrane contains channel proteins which can change shape and spin which aid special movement of substances. Some proteins function as enzymes in speeding up biochemical reactions. The cell surface membrane also consists of carbohydrates chains sometimes found attached to proteins or lipids on the outside of the membrane. These carbohydrates form the glycocalyx which function as protection and in cell recognition as markers for a variety of cell-cell interactions.