Crede’s prophaylaxis is the instilling of ordered

ophthalmic ointment into the newborn’s eyes to avoid

damage and blindness due to conjunctivitis brought
about by Neisseria gonorrhea.
 ACTION: These antibiotic ointments are
bacteriostatic and bactericidal. They provide
prophylaxis against Neisseria gonorrhoeae and
chlamydia trachamatis.
 INDICATION: These medications are applied
to prevent ophthalmia neonatorum in newborns
of mothers who are infected of gonorrhea and
conjunctivitis in newborn of mothers infected
with chlamydia.
 It is part of the routine care of the newborn to give
prophylactic eye treatment against gonorrhea
conjunctivitis or opthalmia neonatorum.

 Neisseria gonorrhea, the causative agent, may be

passed on the fetus from the vaginal canal during
delivery.

 This practice was introduced by Crede, a German

gynecologist in1884. Silver nitrate, erythromycin and
tetracycline ophthalmic ointments are the drugs used
for this purpose.
2. Vitamin K
 Fat soluble vitamin
 Essential for function of blood coagulation
 At birth –
• Reduced vitamin K stores
• Minimal placental transfer
 After birth
• Vitamin K is limited in breast milk (Van Winckel et al, 2008)

 Given IM injection – lateral anterior thigh muscle

 Phytonadione (1mg) = 0.1 cc (mature)
= 0.05 ml (premature)
3. Hepa B Vaccine
Birth dose and interval between the
doses are extremely important :
• not only for the robustness of the
immune response, but
as well for the prevention of vertical and
horizontal transmission and
• the long term protection post-
vaccination.
 Hepatitis B vaccine can
prevent hepatitis B. Hepatitis B is a liver
disease that can cause mild illness
lasting a few weeks, or it can lead to a
serious, lifelong illness.
 Acute hepatitis B infection is a short-
term illness that can lead to fever, fatigue,
loss of appetite, nausea, vomiting,
jaundice (yellow skin or eyes, dark urine,
clay-colored bowel movements), and
pain in the muscles, joints, and stomach.
 Chronic hepatitis B infection is a long-
term illness that occurs when the
hepatitis B virus remains in a person’s
body. Most people who go on to develop
chronic hepatitis B do not have
symptoms, but it is still very serious and
can lead to liver damage (cirrhosis), liver
cancer, and death. Chronically-infected
people can spread hepatitis B virus to
others, even if they do not feel or look
sick themselves.