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In conclusion, hemolytic anaemia may be present in a patient with low haemoglobin levels based
on the blood film findings of high polychromasia, high reticulocyte count, and spherocytes.
Immune hemolytic anaemia, inherited spherocytosis, and autoimmune hemolytic anaemia are
possible reasons of this phenomenon. To distinguish between these disorders and make a
conclusive diagnosis, additional laboratory investigations such as direct antiglobulin testing,
haemoglobin electrophoresis, and osmotic fragility testing may be necessary. Depending on the
underlying cause of the anaemia, several treatment options, such as blood transfusions,
corticosteroids, or splenectomy, may be available. The procedure below summarises all of this
diagnostic data. An algorithm is a flowchart that directs diagnosis by identifying the various
causes using data from lab testing. This provides the chance to include or omit reasons in order
to make a final diagnosis.