MAGNESIUM SULPHATE FOR PRE ECLAMSIA WITH SEVERE FEATURES AND

ECLAMSIA

1. LOADING DOSE-4G OF 20%MGSO4- IV

1g---2mls
4g….??
4g----8mls
To get 20%, 8mls+12mls of water for injection
To get 20mls, equivalent to 4g of 20%mgso4
Give slowly over 5mins
2. MAINTAINANCE DOSE- IM
10g of 50%mgso4, divide into two syringes each with 10mls
5g-equivalent to 10mls
10mls of 50%mgso4, dilute 1 ml of 2%lignocaine
Administer intramusculary in alternate buttock
Continue with maintainance dose 4hourly, for 24 hrs
Until delivery or last fit/convulsion
Which ever comes last

If convulsions occur within 15mins

Give half of iv loading dose

Stop MGSO4 if

Patter reflex is absent

Urine output is less than 100mls for hr

Respiratory rate less than 12

If magnesium sulphate toxicity occur- give calcium gluconate 1g equivalent to

1omls