CHECK LIST FOR PATHOLOGY

DR PREETI SHARMA, MBBS, MD PATHOLOGY, GOLD MEDALLIST

Note: TOPICS IN RED ARE MOST IMPORTANT

CHAPTER SUBTOPICS- CHECKLIST

CELL INJURY Mechanism of apoptosis, Physiological apoptosis

Necroptosis (recent mention of MLKL)
Pyroptosis (esp caspase1,4,5,11)
FERROPTOSIS!!
Autophagy mechanism (macro, micro, CMA, mito)
Table of pigments and stains including
calcification
Examples of cellular adaptations (esp breast,
gravid uterus, barrett’s esophagus)
Cellular ageing: reason, premature ageing
syndromes, Role of sirtuins

INFLAMMATION Sequence of vascular and cellular events

EMPERIPOLESIS, ENTOSIS, NETOSIS
Clinical correlation (LAD,BRUTON’S,CHS,CGD)
IMAGES OF GRANULOMA and GIANT CELLS
TABLE OF EVENTS OF WOUND HEALING (correlate
with surgery)
INTERFERONOPATHIES (UPDATE)
GENETICS Examples (mnemonics) of mendelial disorders
Marfan’s syndrome (fibrillin1 gene)
 Mitochondrial disease pedigree and examples
Genomic imprinting basis of praderwilli and
angelman. Don’t forget beckwith Weidman
FRAGILE X- clinical feature, diagnosis and
premature ovarian failure update (robbins)
DIAGNOSIS OF GENETIC DISORDERS (karyotype,
PCR and types with NGS), PEDIGREE ANALYSIS
CRISPR CAS9 (very very very important)
IMMUNITY All CD markers
TOLERANCE- especially ANERGY, T regulatory
cells, PDL1, CTLA4
AUTOIMMUNE DISORDERS- SLE criteria
ANA PATTERNS ON IMMUNOFLOURESCENCE
ALL IMMUNODEFICIENCY DISORDERS- especially
CVID, SCID, IgA deficiency, WAS
AMYLOIDOSIS (especially structure, table of
diseases, stains, scintigraphy)
NEOPLASIA TABLES-protooncogenes, tumor markers,
paraneoplastic syndromes
Warburg effect
Ames test
Escape of Immune surveillance by tumor cells
Role of PAX genes
DIAGNOSTIC MODALITIES-FNAC, IHC, IF, EM
CVS Cardiomyopathymed-correlation (esp DCM causes, HCM
images, ARVCM genetics)
Endocarditismed-correlation especially IE and Robbins
photos of vegetations
TABLE OF EVENTS in myocardial infarction
 Cardiac tumors- location, microscopy, syndrome of
MYXOMA AND RHABDOMYOMA.
Image of papillary fibroelastoma
BLOOD VESSELS VASCULITISmed-correlation ESPECIALLY GCA,
PAN,SMALL VESSEL-ANCA (with images)
Microorganisms related to atherosclerosis
Hypertension changes in blood vessels
Vascular tumor- hemangioma, lymphangioma in
turner syndrome, painful presentation of glomus
tumor, Kaposi sarcoma in HIV patient, staghorn
vessels in hemangiopericytoma
LUNG COVID CHANGES-ARDS
Stages of typical pneumonia , Atypical pneumonia,
Hecht’s pneumonia, aspiration pneumonia
Asthma images, relation to
ADAM,IL13,YKL40,ATOPY
REID index increased in chronic bronchitis
Restrictive lung disease- silicosis, asbestosis,
berylliosis, bagassosis
Granulomatous diseases- foci of TB, all about
sarcoidosis
Lung tumor start to end—especially lepidic
variant, genes, IHC
Mesothelioma- relation to asbestos, BAP40 gene,
electron microscopy
GIT Salivary gland tumorscorrelation with surgery
Esophagus- achalasia causes and barium study
Stain for Barrett eso, image-gross and endoscopy
Esophageal tumor-risk factors
Stress ulcer-cushing and curling
 Stomach adenocarcinoma- lauren’s classification
ALL ABOUT GIST (genetics, gross, microscopy,
markers, treatment, pediatric gist)
MALTOMA-t(11;18), H.pylori, LEL
STAINS FOR H.PYLORI
INTESTINE IS IMPORTANT START TO END
MALABSORPTION: whipple diagnosis, celiac
pathogenesis and diagnosis, IPEX,
Abetalipoproteinemia
INFECTIONS-esp cryptosporidium, microsporidia
ALL POLYPS-esp hamatomatous, SSA,FAP
INTESTINAL CANCER- GENETICS
LIVER HEPATITIS changes morphological
Hepatitis serology graphs
Syndromes- Criggler Najjar, Dubin Jonson, Gilbert,
Rotor
Differences of PBC and PSC (antibodies, onion
skinning)
LATEST FAVORITE-autoimmune hepatitis
Hemochromatosis and Wilson disease to be
correlated with medicine
ALL RECENT ADVANCES OF HEPATIC ADENOMAS
HCC variant fibrolamellar carcinoma
FNH- ocp use, gross, radio
Miscpeds correlation-ALAGILLE SYNDROME, CAROLI
DISEASE
KIDNEY View the two lectures (free classes of unacademy)
(EVERYTHING IS Nephrotic nephritis (microscopic appearances-
IMPT) light,electron,IF,silver stain)
MPGN (INICET)
 CPN MICROSCOPY
CASTS CRYSTALS (very very very impt)
All about renal tumors
MALE and FEMALE View KSM of ovarian and testicular tumors (its
GENITAL SYSTEM enough)
Endometrial cancer genetics tables (POLE gene
added in robbins 10th edition)
Gleason grading of prostate cancer- KSM

SKIN IMMUNOFLUORESCENCE BULLOUS DISORDERS

BONE TUMORS- KSM (expecially ewings sarcoma,
chondroblastoma, osteocarcoma, syndromes)
MUSCLE POLYMYOSITIS, DERMATOMYOSITIS, DMD, BMD
ENDOCRINE THYROID TUMORS- KSM
PHEOCHROMOCYTOMA GENETICS AND
HISTOPATHOLOGY (UPDATED TABLE ROBBINS)
PITUITARY TUMORS- GENETICS TABLE ROBBINS