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  • Friability Tester: Principal:: Laboratory Technique Pharmaceutical Industry Tablets

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    Tanvi Zakarde
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    The friability tester determines the durability of tablets by measuring the amount of material lost from their surfaces when subjected to mechanical stress. Tablets are placed in a drum that rotates for a set time, simulating the stress of transportation and handling. The tablets are then reweighed and the percentage of mass lost is calculated, with most formulations allowing only a small amount of surface material to wear off and no complete fractures. This test is important for quality control and ensuring tablets will remain intact during production, storage, and use.

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    The friability tester determines the durability of tablets by measuring the amount of material lost from their surfaces when subjected to mechanical stress. Tablets are placed in a drum that rotates for a set time, simulating the stress of transportation and handling. The tablets are then reweighed and the percentage of mass lost is calculated, with most formulations allowing only a small amount of surface material to wear off and no complete fractures. This test is important for quality control and ensuring tablets will remain intact during production, storage, and use.

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    24 views1 page

    Friability Tester: Principal:: Laboratory Technique Pharmaceutical Industry Tablets

    Uploaded by

    Tanvi Zakarde
    The friability tester determines the durability of tablets by measuring the amount of material lost from their surfaces when subjected to mechanical stress. Tablets are placed in a drum that rotates for a set time, simulating the stress of transportation and handling. The tablets are then reweighed and the percentage of mass lost is calculated, with most formulations allowing only a small amount of surface material to wear off and no complete fractures. This test is important for quality control and ensuring tablets will remain intact during production, storage, and use.

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    FRIABILITY TESTER :

    PRINCIPAL : Tablet friability can be used to measure


    efficiency of tabletting equipment or as an indicator of
    formulation suitability as well as routine QC functions. It can
    also be thought of as measuring “dusting”. Tablets are rotated
    in a plastic drum for a specified period of time. A gravimetric
    determination is then made to quantitate the amount of
    surface material that has worn off.
    WORKING: Friability testing is a laboratory
    technique used by the pharmaceutical industry to test
    the durability of tablets during transit. This testing
    involves repeatedly dropping a sample of tablets over a
    fixed time, using a rotating wheel with a baffle. The
    result is inspected for broken tablets, and the
    percentage of tablet mass lost through chipping. A
    typical specification will allow a non-zero percentage of
    chipping, and zero broken tablets.

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