45- 024 Synthesis of Heterogeneous Enzyme—Metal Nanoparticle Biohybrids in Aqueous Media and Their Applications in C—C Bond Formation and Tandem Catalysis. — Novel enzyme/metal nanoparticles nanobiohybrids synthesized in aqueous medium are used as multivalent catalysts in various sets of synthetic reactions even at ultra-low concentrations (ppb amount). They act as a reducing agent for nanoparticle formation, stabilizing agent to avoid aggregation, and as a biocatalyst. — (FILICE, M.; MARCIELLO, M.; DEL PUERTO MORALES, M.; PALOMO*, J. M.; Chem. Commun. (Cambridge) 49 (2013) 61, 6876-6878, http://dx.doi.org/10.1039/c3cc42475h ; Dep. Biocatal., Inst. Catal., CSIC, E-28049 Madrid, Spain; Eng.) — M. Duhs