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Efficiency of self-ligating vs conventionally


ligated brackets during initial alignment
Emily Ong,a Hugh McCallum,b Mark P. Griffin,c and Christopher Hod
Brisbane and Herston, Queensland, Australia

Introduction: The aim of this study was to compare the efficiency of self-ligating (SL) and conventionally
ligated (CL) brackets during the first 20 weeks of extraction treatment. Methods: Study models of 50 consec-
utive patients who had premolar extractions in the maxillary and/or mandibular arch, 0.022 3 0.028-in slot
brackets, and similar archwire sequences were examined. Forty-four arches received SL Damon 3MX
brackets (Ormco, Glendora, Calif), and 40 arches received either CL Victory Series (3M Unitek, Monrovia,
Calif) or Mini-Diamond (Ormco) brackets. The models were evaluated for anterior arch alignment, extraction
spaces, and arch dimensions at pretreatment (T0), 10 weeks (T1), and 20 weeks (T2). Results: There were no
significant differences between the SL and CL groups at 20 weeks in irregularity scores (mandibular arch,
P 5 0.54; maxillary arch, P 5 0.81). There were no significant differences in passive extraction space closures
between the SL and CL groups (mandibular arch, T0-T2, P 5 0.85; maxillary arch, T0-T2, P 5 0.33). Mandibular
intercanine widths increased from T0 to T2: 1.96 and 2.86 mm in the SL and CL groups, respectively. This was not
significant between the groups (P 5 0.31). Logistic regression did not show a difference between the SL and CL
bracket groups. Conclusions: SL brackets were no more efficient than CL brackets in anterior alignment or
passive extraction space closure during the first 20 weeks of treatment. Ligation technique is only one of
many factors that can influence the efficiency of treatment. Similar changes in arch dimensions occurred,
irrespective of bracket type, that might be attributed to the archform of the archwires. (Am J Orthod
Dentofacial Orthop 2010;138:138.e1-138.e7)

highlighted the limitations of in-vitro studies.3 In partic-

B
racket designs have undergone continual modifi-
cations since fixed appliances were first used in ular, studies that demonstrate reduced friction in SL
orthodontics. The quest to improve treatment brackets compared with conventionally ligated (CL)
efficiency has culminated in many modern edgewise brackets have been coupled with small-diameter wires
appliances. Recently, the promotion of self-ligating in well-aligned arches with no tip and torque.4-9 In-
(SL) brackets has incited much controversy. Advocates vitro studies are limited because they cannot compre-
claim that low-friction SL brackets coupled with light hensively simulate a clinical scenario. Many variables
forces enhance the rate of tooth movement and decrease can influence the amount of friction generated in a fixed
treatment time. Other advantages include decreased appliance system. These include archwire and bracket
appointment times, improved oral hygiene, increased composition,10 archwire dimension,11 bracket slot
patient acceptance, and superior treatment results.1,2 dimension and design, interbracket distance, deflection
Most claims of SL brackets have been extrapolated of the archwire,12 and biologic factors such as saliva11
from in-vitro studies. A recent systematic review and perturbations.13 Therefore, it is questionable
whether the use of SL brackets translates into clinical
benefits such as decreased resistance to sliding, faster
a
Postgraduate student, Discipline of Orthodontics, School of Dentistry, tooth movement, and increased treatment efficiency.
University of Queensland, Brisbane, Queensland, Australia. Several in-vivo studies have compared the
b
Senior Dental Specialist (Orthodontics), Royal Children’s Hospital, Herston,
Queensland, Australia. efficiency of SL and CL brackets during various stages
c
Research fellow, School of Population Health, University of Queensland, of treatment with conflicting results. These studies
Herston, Queensland, Australia. measured treatment efficiency in terms of total treat-
d
Associate professor, Discipline of Orthodontics, School of Dentistry, Univer-
sity of Queensland, Brisbane, Queensland, Australia. ment times, numbers of appointments, and tooth move-
The authors report no commercial, proprietary, or financial interest in the prod- ment during initial alignment and active space closure.
ucts or companies described in this article. Early retrospective studies reported up to 6 months’
Reprint requests to: Christopher Ho, University of Queensland, School of Den-
tistry, 200 Turbot St, Brisbane, QLD 4000, Australia; e-mail, Christopher_Ho@ reduction in total treatment time and 7 fewer appoint-
health.qld.gov.au. ments with SL brackets.2,14 Subsequent well-designed
Submitted, October 2009; revised and accepted, January 2010. retrospective and prospective studies reported no signif-
0889-5406/$36.00
Copyright Ó 2010 by the American Association of Orthodontists. icant differences during initial alignment or active space
doi:10.1016/j.ajodo.2010.03.020 closure with various SL and CL brackets.15-20
138.e1
138.e2 Ong et al American Journal of Orthodontics and Dentofacial Orthopedics
August 2010

Miles et al15 and Miles17 postulated that SL brackets study models were available at pretreatment (T0), 10
might provide a measurable benefit in extraction weeks (T1), and 20 weeks (T2) postbonding; (4)
patients. Additionally, Scott et al19 suggested that SL treatment included 0.022 3 0.028-in slot brackets (SL
brackets might encourage passive space closure during brackets, Damon 3MX, Ormco, Glendora, Calif; or
initial alignment. There is a relative lack of evidence CL brackets, Victory Series, 3M Unitek, Monrovia,
comparing the efficiency of SL and CL brackets in Calif, or Mini-Diamond, Ormco); (5) treatment began
extraction patients because most studies have investi- with an initial archwire of 0.014-in copper-nickel-
gated mixed samples. Only 2 clinical trials have titanium (Damon archform, Ormco), followed by
compared SL and CL brackets solely in extraction 0.014 3 0.025-in copper-nickel-titanium (Damon arch-
patients.16,19 One study investigated the initial form, Ormco)21; (6) the patients were reviewed every 5
alignment phase and reported no difference between weeks; and (7) the first archwire was left in place until
SL and CL brackets.19 Neither clinical trial investigated the teeth were passively engaged in all bracket slots
the efficiency of passive space closure during alignment. before proceeding to the second archwire.
If there is a measurable advantage of SL brackets, then it The following exclusion criteria were applied: treat-
should be most apparent during alignment and space ment with nonsymmetrical extractions, no impacted or
closure when the bracket slides along the archwire. In unerupted permanent teeth anterior to the first molars
this study, passive space closure was defined as the ex- in the arch that received extractions, treatment with
traction space closure during alignment without active removable appliances or rapid maxillary expansion
space-closing mechanics. The amount of passive space appliances, and incomplete records at a time point.
closure varies greatly between patients, but this param- Fifty patients (20 male, 30 female) fulfilled the
eter has not been investigated before. If the use of SL inclusion criteria.
brackets could achieve greater passive space closure, Pretreatment characteristics were recorded includ-
there would be less extraction space to close actively. ing the patient’s age bonding, sex, mandibular and max-
This could reduce the overall treatment time. Further- illary crowding, irregularity index, extraction space,
more, this might minimize the detrimental effects of ac- intercanine width, intermolar width, and arch depth.
tive force application such as root resorption. All study models were evaluated by using Little’s
In this study, we aimed to determine whether there irregularity index22 to quantify the alignment of the 6
are significant differences in the efficiency of anterior anterior teeth. Crowding was calculated as the differ-
tooth alignment and the amount of passive space closure ence between the sum of tooth widths and arch circum-
between SL and CL brackets. Concomitant changes in ference taken from the line of best fit, through the
arch dimensions were also compared between the SL contact points mesial to the first molars, on a photocopy
and CL bracket groups. of the patient’s occlusal archform.
Extraction space was measured from the closest
points on the adjacent teeth before extraction. The
MATERIAL AND METHODS mesiodistal widths of the teeth to be extracted were
Ethical approval was obtained from the Dental Sci- not used because they were often displaced from the
ences and Research Ethics Committee of the University archform; this decreased the extraction space to be
of Queensland School of Dentistry and the Royal Child- closed. Similarly, extraction spaces at T1 and T2
ren’s Hospital and Health Services District Ethics Com- were measured from the closest points on the crowns
mittee. Study models of 50 consecutive patients who of the teeth on either side of the extraction space. The
received comprehensive full fixed appliance treatment contact points were not used because many teeth were
with 0.022 3 0.028-in slot brackets at the School of rotated.
Dentistry, University of Queensland and the Royal Intercanine widths were measured from the cusp
Children’s Hospital were examined. tips of the canines. Measurements were not taken
The dental school patients were treated by postgrad- from the gingival margin because the quality of the gin-
uate students under the supervision of an experienced gival impression was inconsistent. Intermolar widths
orthodontist. Royal Children’s Hospital patients were were measured from the central and mesial occlusal
treated by an experienced orthodontist (H.M. or C.H.). pits of the mandibular and maxillary first molars
Patient records were included if they satisfied the because this area of the impression was clearer than
following inclusion criteria: (1) treatment began the cusps. Arch depth was measured as the perpendicu-
between 10 and 18 years of age; (2) treatment included lar distance from a line drawn through the mesial
bilateral mandibular or maxillary extractions followed contact points of the first molars to the labial surfaces
by fixed appliance therapy; (3) intraoral photos and of the central incisors.
American Journal of Orthodontics and Dentofacial Orthopedics Ong et al 138.e3
Volume 138, Number 2

Wax was applied to cover the brackets on each Table I. Sample sizes at T0, T1, and T2
model before measurement. An identification number Mandibular arch Maxillary arch
was assigned to each model. Therefore, the researcher
(E.O.) was blinded to patient name, time point, and SL CL SL CL
bracket type during data collection to minimize system- T0 19 18 25 22
atic error. The study models were measured with elec- T1 19 18 25 22
tronic calipers with sharpened tips that were accurate T2 19 14 25 16
to 0.01 mm (Mitutoyo, Tokyo, Japan). All model mea-
surements were made by the principal researcher (E.O.).
The average differences between the measurements
Statistical analysis were 0.07 6 0.52 mm for the irregularity index and
0.06 6 0.33 mm for extraction space.
The difference in irregularity scores was used to
Fifty patients (20 male, 30 female) fulfilled the in-
determine the sample size. Based on a previous study,
clusion criteria. This gave a total of 84 arches; 44 arches
a clinically significant difference of 0.98 mm in irregu-
were treated with SL brackets and 40 arches with CL
larity score, at a power of 80% and a level of signifi-
brackets. In the CL sample, 18 arches received Mini-
cance of 0.05, would require a minimum of 17
Diamond brackets. The numbers of arches included in
patients per treatment group.19 In the final sample of
the statistical analysis for each bracket group at T0,
50 patients, 44 arches were treated with SL brackets
T1, and T2 are summarized in Table I. No SL arches
and 40 arches with CL brackets.
were excluded. Six CL maxillary arches were excluded
Statistical analysis was performed by using Mini-
from analysis at T2 because 5 models were missing, and
tab software (release 15, Minitab, State College, Pa)
1 patient received a different archwire sequence. Four
and SAS software (version 9.2, SAS Institute, Cary,
mandibular arches were also excluded at T2 because
NC). The mandibular and maxillary arches were
of missing models.
analyzed separately. Descriptive statistics were calcu-
The mean irregularity index scores decreased in
lated, and the data were checked for normality.
both bracket groups over time (Table II). Both groups
Two-sample t tests were performed at T0, T1, and
had greater decreases in irregularity during the first 10
T2 to compare the bracket groups for irregularity
weeks of treatment compared with the subsequent 10
scores, residual extraction spaces, intercanine widths,
weeks.
intermolar widths, and arch depths. The amounts of
Over 20 weeks, the mean irregularity scores in the
passive extraction space closure from T0 to T1, T1
SL group decreased from 10.88 to 2.84 mm in the man-
to T2, and T0 to T2 for each bracket group were
dibular arch, and from 11.98 to 4.37 mm in the maxil-
also calculated and compared by using 2-sample
lary arch. Scores in the CL group decreased from
t tests. A chi-square goodness-of-fit test was used to
12.52 to 2.45 mm in the mandibular arch, and from
determine whether the male-to-female ratio was
12.53 to 4.16 mm in the maxillary arch.
significantly different between the bracket groups.
There were no statistically significant differences
Logistic regression was also used to determine
between the treatment groups at T1 or T2 in the mandi-
whether there was a difference between the SL and
ble (T1, P 5 0.81; T2, P 5 0.54) or the maxilla (T1,
CL bracket groups. Regression coefficients and confi-
P 5 0.87; T2, P 5 0.81).
dence intervals were calculated for each variable (age,
For passive extraction space closure, the residual ex-
sex, irregularity index, intercanine width, intermolar
traction spaces were measured, and the left and right
width, and arch depth) for both arches. Multiple impu-
sides were averaged for each patient. The mean residual
tation was used to account for missing data.
extraction spaces for each bracket group at T1 and T2
Intraexaminer reliability was assessed by remeasur-
were then calculated (Table II). There were no significant
ing 20 subjects at least 4 weeks after the original
differences in residual extraction spaces between the
measurements. A t test was performed to compare the
groups at T1 or T2 in the mandible (T1, P 5 0.35; T2,
first and second measurements.
P 5 0.99) or the maxilla (T1, P 5 0.37; T2, P 5 0.44).
Overall space closure from T0 to T2 was similar in
RESULTS both arches. The differences were less than 1 mm and
Intraexaminer reliability was high. There were no not statistically significant.
statistically significant differences between the first The mean changes in arch dimensions from T0 to T2
and second measurements for irregularity index were calculated for each arch (Table III). There were no
(P 5 0.51) and extraction space closure (P 5 0.38). statistically significant differences between the groups
138.e4 Ong et al American Journal of Orthodontics and Dentofacial Orthopedics
August 2010

Table II. Descriptive statistics for the irregularity index and mean extraction space (2-sample t test)
Mandibular arch Maxillary arch

SL mean (SD) CL mean (SD) P value SL mean (SD) CL mean (SD) P value

Irregularity index, T0 10.88 (4.72) 12.52 (5.26) 0.33 11.98 (5.55) 12.53 (7.2) 0.78
Mean extraction space, T0 7.74 (0.75) 7.78 (0.96) 0.84 7.98 (1.92) 8.12 (1.17) 0.67
Irregularity index, T1 4.38 (3.63) 4.12 (2.87) 0.81 5.44 (3.72) 5.64 (4.46) 0.87
Mean extraction space, T1 5.45 (1.43) 4.98 (1.56) 0.35 5.51 (1.74) 5.04 (1.73) 0.37
Irregularity index, T2 2.84 (1.86) 2.45 (1.72) 0.54 4.37 (2.69) 4.16 (2.59) 0.81
Mean extraction space, T2 4.02 (1.78) 4.03 (1.65) 0.99 4.30 (2.13) 3.83 (1.76) 0.44

Table III. Mean changes in arch dimensions (T0-T2) in millimeters (2-sample t test)
Mandibular arch Maxillary arch

SL mean (SD) CL mean (SD) P value SL mean (SD) CL mean (SD) P value

Intercanine width 1.96 (1.78) 2.86 (2.80) 0.31 2.83 (2.49) 3.40 (4.12) 0.63
Intermolar width 1.44 (1.54) 1.34 (2.10) 0.88 0.25 (2.08) 0.14 (1.87) 0.87
Arch depth 1.69 (2.63) 1.08 (1.03) 0.61 2.42 (3.99) 1.37 (2.87) 0.33

for any changes in arch dimensions in either arch. In DISCUSSION


both groups, mandibular intercanine widths increased Studies have demonstrated that SL brackets gener-
(P 5 0.31), intermolar widths decreased (P 5 0.88), ate significantly lower levels of in-vitro friction than
and arch depths decreased (P 5 0.61). In the maxillary do CL brackets.4-9,23 This has led to the promotion of
arch, intercanine widths increased (P 5 0.63), intermo- SL brackets on the assumption that decreased friction
lar widths increased (P 5 0.87), and arch depths leads to enhanced clinical efficiency. However, our
decreased (P 5 0.33). study concurs with the growing body of evidence that
The changes were greatest in mandibular and max- there is no statistically significant difference in
illary intercanine widths. Mandibular intercanine treatment efficiency between SL and CL brackets
widths increased from T0 to T2: 1.96 and 2.86 mm in during initial alignment. Our study demonstrated that
the SL and CL groups, respectively. Maxillary interca- Damon 3MX SL brackets were no more efficient than
nine widths increased from T0 to T2: 2.83 and 3.4 Victory Series and Mini-Diamond CL brackets in
mm in the SL and CL groups, respectively. anterior alignment or passive extraction space closure
Logistic regression was used to determine whether during the first 20 weeks of orthodontic treatment.
there was a difference between the SL and CL bracket Early clinical studies by Eberting et al2 and Harra-
groups. Multiple imputation was used to account for dine14 reported decreased total treatment times and
the small amount of missing data at T2. The following fewer appointments for patients treated with Damon
variables were tested at 0, 10, and 20 weeks: age, sex, SL brackets. However, these retrospective studies
irregularity index, intercanine width, intermolar width, were both potentially subject to bias. The effect of con-
and arch depth. founding factors might have been considerable because
Regression coefficients and confidence intervals the selection criteria were not well detailed, the pretreat-
were calculated for each variable in both arches ment characteristics of the sample were not tested for
(Tables IV and V). The confidence intervals also equivalence,2 and clinical variables such as archwire se-
included the variance because of missing data. quences were different in each bracket group.14
All regression coefficients were close to zero, except Subsequent well-designed retrospective and
sex and intermolar width at T2, which also had large prospective clinical studies reported no significant
confidence intervals. No variable was significantly asso- differences in treatment efficiency between SL and
ciated with the probability of reduction in irregularity in CL brackets during initial alignment15,17-20 and active
either arch. Arch depth at T2 had borderline significance space closure.16 Most of these studies evaluated the
for the maxillary arch but was not considered highly alignment efficiency of the mandibular anterior arch
significant (particularly because of the multiple compar- because rotations, irregularity, and small interbracket
isons in this study). distances are typically encountered in this region.
American Journal of Orthodontics and Dentofacial Orthopedics Ong et al 138.e5
Volume 138, Number 2

Table IV. Logistic regression for the mandibular arch


Parameter Estimate of regression coefficient 95% CI P value

Age 0.09 0.80 0.61 0.80


Sex 1.55 4.18 1.07 0.25
Irregularity index, T0 0.20 0.27 0.68 0.40
Intercanine width, T0 0.71 1.67 0.24 0.14
Intermolar width, T0 0.74 0.38 1.85 0.19
Arch depth, T0 0.35 0.24 0.93 0.25
Extraction space, T0 0.17 1.98 1.63 0.85
Irregularity index, T1 0.20 0.90 0.49 0.56
Extraction space, T1 0.56 1.93 0.81 0.42
Irregularity index, T2 0.35 1.44 0.73 0.52
Intercanine width, T2 0.53 0.53 1.60 0.32
Intermolar width, T2 1.10 2.70 0.49 0.17
Arch depth, T2 0.09 0.73 0.90 0.83
Extraction space, T2 0.49 0.65 1.63 0.40

Table V. Logistic regression for the maxillary arch


Parameter Estimate of regression coefficient 95% CI P value

Age 0.30 0.92 0.32 0.34


Sex 0.35 2.09 2.79 0.78
Irregularity index, T0 0.01 0.19 0.21 0.91
Intercanine width, T0 0.08 0.29 0.46 0.66
Intermolar width, T0 0.13 0.64 0.39 0.63
Arch depth, T0 0.19 0.27 0.65 0.40
Extraction space, T0 0.21 0.73 0.31 0.42
Irregularity index, T1 0.05 0.31 0.41 0.80
Extraction space, T1 0.07 0.81 0.96 0.87
Irregularity index, T2 0.00 0.48 0.49 0.99
Intercanine width, T2 0.14 0.70 0.41 0.60
Intermolar width, T2 0.23 0.58 1.05 0.56
Arch depth, T2 0.78 1.54 0.03 0.04
Extraction space, T2 0.72 0.31 1.74 0.16

We investigated the anterior alignment of both arches extraction spaces because of reduced friction during
with the irregularity index. alignment could be a time-saving benefit.19 Therefore,
Various authors have drawn the same conclusions we exclusively investigated extraction subjects during
irrespective of the particular brand of SL bracket. Miles initial orthodontic treatment to assess the efficiency of
et al15 and Miles17 did not find any significant differ- alignment and passive extraction space closure.
ences when they prospectively compared Damon SL Two previous studies compared SL and CL brackets
and SmartClip (3M Unitek) SL with Victory Series solely in extraction patients. Miles16 prospectively com-
CL brackets during initial alignment. Pandis et al18 pared 0.018-in Victory series CL brackets and Smart-
also found no difference when comparing the time to Clip SL brackets during active space closure. He
alignment in the mandibular arch between Damon 2 found no differences in the rate of tooth movement
(Ormco) SL and Microarch (GAC International, Bohe- between the bracket types: 1.1 mm per month with SL
mia, NY) CL brackets. A recent large retrospective brackets and 1.2 mm per month with CL brackets. These
study concluded that InOvation (GAC) SL brackets rates are not comparable with our results because of dif-
had no measurable advantages over Victory Series CL ferent biomechanics and types of tooth movement dur-
brackets in initial alignment time, total treatment time, ing these stages.
or number of appointments.20 Scott et al19 conducted a randomized controlled trial
Despite these findings, it has been suggested that SL of patients having mandibular first premolar extractions.
brackets might provide benefits for extraction patients He concluded that Damon 3MX brackets were no more
during initial alignment or space closure.15,17 efficient during mandibular alignment than Synthesis
Correspondingly, spontaneous tooth movement into (Ormco) CL brackets. Those authors did not investigate
138.e6 Ong et al American Journal of Orthodontics and Dentofacial Orthopedics
August 2010

the maxillary arch or passive extraction space closure. minimize confounding factors. Therefore, the critical
Our study is the first to quantify the amount of tooth difference between the treatment groups was the
movement during passive extraction space closure. We method of ligation.
found no difference in the amount of passive space This study had several limitations. There was no
closure during initial alignment, in either arch, between control group available to measure the natural drift of
the bracket types. the teeth into the extraction spaces without orthodontic
We used the same initial archwire sequence as that appliances. It could also be argued that extraction ther-
of Scott et al,19 which included 0.014-in and 0.014 3 apy is not routinely performed with the SL bracket phi-
0.025-in copper-nickel-titanium archwires in the Damon losophy and is not intended for this sample of patients.
archform. The SL group of Pandis et al18 also used the Despite the strict inclusion and exclusion criteria, the
same sequence. Similar changes in arch dimensions possibility of sampling bias because of the retrospective
were observed in all patients with these archwires nature of the study cannot be dismissed. Several patients
regardless of the bracket type used. Therefore, the were excluded because of missing models at the various
dimensional changes can be attributed to the Damon arch- time points, or they received an alternate archwire
form. Mean mandibular intercanine widths increased, sequence that reduced the power of the study at T2.
mandibular intermolar widths decreased, and arch depths The patients were also treated by several clinicians
decreased. Mandibular intercanine widths increased by with various levels of experience. The 3 bracket types
averages of 1.96 and 2.86 mm in the SL and CL groups, used in this study had different prescription values.
respectively. Scott et al19 reported similar increases of It might be postulated that, as irregularity increases,
2.55 and 2.66 mm in SL and CL groups, respectively. other factors negate any benefit of the reduced friction
Mean maxillary intercanine widths increased by of SL brackets. For example, the narrower bracket
2.83 and 3.4 mm in the SL and CL groups, respectively. design of the Damon 3MX might have increased the
The increases in maxillary intermolar widths in both contact angle and contributed to elastic binding and
bracket groups were negligible. Interestingly, maxillary notching. Future research could explore these hypothe-
and mandibular intercanine widths increased despite the ses in extraction patients, with larger sample sizes in
extractions. This might be due to the distal movement of a prospective clinical trial.
the canines into the extraction spaces.19 These findings It is not surprising that bracket type does not appear to
discredit previous suggestions that premolar extractions have a significant influence on treatment efficiency. Treat-
inevitably cause ‘‘shrinking’’ of the dental arch, in- ment efficiency is the product of many mechanical and bi-
creased buccal corridors, and damage to smile es- ologic factors. It is unlikely that any 1 factor is responsible
thetics.24 Furthermore, studies have shown that buccal for the rate of tooth movement. The biology of tooth
corridors do not influence smile esthetics.25,26 movement is a complex and highly coordinated process
The results from this study concur with previous at the cellular, molecular, and genetic levels. Individual
studies that found no difference in the alignment of man- variation undoubtedly has a fundamental underlying role
dibular teeth in extraction patients with severe in tooth movement and treatment efficiency.
irregularity.18,19 The mean irregularity scores in the
study of Scott et al19 were 12.44 mm in the CL group CONCLUSIONS
and 11.23 mm in the SL group. Similarly, the patients
we investigated had severe irregularity scores. Pandis 1. SL brackets were no more efficient than CL
et al18 investigated moderate and severe irregularity. They brackets in anterior alignment and passive extrac-
reported no significant difference in subjects with severe tion space closure during the first 20 weeks of
irregularity scores greater than five. Interestingly, they orthodontic treatment.
found that patients with moderate irregularity, with irreg- 2. Changes in arch dimensions were similar in the SL
ularity scores between 2 and 5, were 2.7 times more likely and CL groups.
to align faster in the SL bracket treatment group. Differ-
ent archwire sequences were used in each bracket group We thank the Australian Society of Orthodontists’
in the study of Pandis et al18; this might have been a con- Foundation for Research and Education for providing
founding factor contributing to the hazard ratio. a grant to fund this research project.
A strength of this study was the inclusion and exclu-
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