1.

All of the following statements about Gynaecomastia are true except:

Subcutaneous mastectomy is the initial treatment of choice.
Seen in liver disease.
There may be estrogen – testosterone imbalance.
Can be drug induced.
2. The cambium layer is seen in:
Embryonal rhabdomyosarcoma.
Pleomorphic rhabdomyosarcoma.
Alveolar rhabdomyosarcoma.
Undifferentiated rhabdomyosarcoma.
3. which of the following HLA subtype is most characteristically associated with
Rheumatoid arthritis
HLA DRI.
HLA DR2.
HLA DR5.
HLA DR4.
4. Characteristic features of basal cell carcinoma are:
Keratin pearls.
Foam cells.
Nuclear palisading.
Psammoma bodies.
5. A 45 year old female had bloody nipple discharge
Intraductal papilloma.
Duct ectasia.
Fibrocystic breast disease.
Hyperprolactinemia.
6. Acanthosis nigricans is seen in:
GI malignancy.
lung cancer.
breast cancer.
all of the above.
7. Margins of squamous cell carcinoma are:
Inverted.
Everted.
Rolled.
Undermined.
8.Amaurotic cats eye reflex is seen in:
Papilloedema.
Retinoblastoma.
Papillitis.
Retinitis pigmentosa.
9. The commonest clinical pattern of basal cell carcinoma is:
Nodular.
Morpheaform.
Superficial.
Keratotic.
10. A female patient has nipple discharge with multiple ill defined breast lumps in
both breast. Most likely diagnosis?
Intraductal papilloma.
Duct ectasia.
Fibrocystic breast disease.
Hyperprolactinemia.
11. Which of the following is the initial site of disease in RA?
Cartilage.
Synovium.
Bone.
Tendon.
12. Cerebellar hemangioblastoma and retinal tumors are seen in:
VHL syndrome.
NF -1.
Tuberous sclerosis.
NF – 2.
13. The most common malignancy found in Marjolin’s ulcer is:
Basal cell carcinoma.
Squamous cell carcinoma.
Malignant fibrous histiocytoma.
Neutrophic malignant melanoma.
14. Heberden’s arthropathy affects:
Lumbar spine.
Symmetrically large joints.
Sacroiliac joints.
Distal interphalangeal joints.
15. Molecular classification of breast cancer is based on:
Serum hormone levels.
Expression of hormone receptors (ER/PR).
In-vitro response to chemotherapeutic agents.
Gene expression profiling.
16. Bowen’s disease is:
Mimics chronic dermatosis.
Premalignant condition.
Presents with pruritus.
All of the above.
17. Which of the following is the most common type of glial tumors?
Astrocytomas.
Medulloblastomas.
Neurofibromas.
Ependymomas.
18. Type of anemia seen in Rheumatoid arthritis is:
Microcytic hypochromic anemia.
Macrocytic normochromic anemia.
Normocytic hypochromic anemia.
Normocytic normochromic anemia.
19. Most common soft tissue tumor is:
Fibroma.
Lipoma.
Leiomyosarcoma.
Leiomyoma.
20. True about Paget’s disease of the nipple is:
Always there is underlying carcinoma.
Often bilateral eczema of nipple seen.
Histology reveals giant cells.
Highly malignant.