Stem cell-based Regenerative Prosthodontics

ABSTRACT

Background
Dentistry is a continuously changing field that has witnessed much
advancement in the past century.
Recent development of stem cell-based regenerative medicine has
introduced the concept of “regenerative prosthodontics” to our field.
Mesenchymal stem/stromal cells (MSCs) are now an excellent
candidate for tissue replacement therapies, and tissue engineering
approaches and chair-side cellular grafting approaches using
autologous MSCs represent the clinical state of the art for stem-cell-
based alveolar bone regeneration. Of the available regenerative
treatment options, craniofacial tissue regeneration using mesenchymal
stem cells (MSCs) shows promise.
Summary & conclusion
Among the available hydrogel biomaterials for cell encapsulation,
alginate-based hydrogels have shown promising results in biomedical
applications. Alginate scaffolds encapsulating MSCs can
provide a suitable microenvironment for cell viability and
differentiation for tissue regeneration applications. This poster aims
to summarize current applications of dental-derived stem cell therapy
and highlight the use of alginate-based hydrogels for applications in
craniofacial tissue engineering.

KEYWORDS- STEM CELLS, CRANIOFACIAL REGENERATIONS,

TISSUE ENGINEERING,MSCs

C PRADEEP
BISMA KHAN