Vigilancia Tecnológica

Esteban Cuadros Correa

Química Industrial

1. Select a search Project (Maximum 15 words)

“Prediction of smell in molecules based on chemical structure using AI”
2. Select 5 different search formulas for scientific articles in SCOPUS
3. Report for each search the person who is the most public, the place of origin, number of
publications, number of citations.
4. Find the year with the highest citation and make the graphs by area, by author, by affiliation
and by funding funds.
a. Prediction AND of AND smell AND artificial AND intelligence
TOTAL OF ARTICLES: 37

Only a few authors publish about this topic, and 3 of them have the same number of
publications: Jain, S.; Kaur, K.; Kerdcharoen, T.

The country that is most interested about this topic appears to be India, with 11
documents.
In total, the number of citations until 3/03/2023 is 404. The most citations were done in 2019,
related to the COVID-19 pandemics.
The year with more publications was 2021, and the graphs for this year are shown below.
b. Smells AND artificial AND intelligence
TOTAL OF ARTICLES: 206

The person that publishes the most is Kodogiannis, V.S.

The majority of articles are from India.

In total, the number of citations until 3/03/2023 is 3409.
The year with more publications was 2022, and the graphs for this year are shown below.
c. Smells AND artificial AND intelligence + Limited to Chemistry
TOTAL OF ARTICLES: 6

Because of the low number of articles, no discrimination can be made by autor.

Only by one extra article, the country that publishes the most is South Korea.
 In total, the number of citations until 3/03/2023 is 113.
Since the are only 6 articles, each articles corresponds to a different year, and there is
not a year with more publications than the other.
d. Smell AND prediction AND machine AND learning + Limited to Document type: Article or
Review.
TOTAL OF ARTICLES: 59

Two authors have three articles: Nakamoto, T.; Palomba, F.

The country with most publications is the United States.

In total, the number of citations until 3/03/2023 is 798.
The year with more publications was 2022, and the graphs for this year are shown below.
e. Smell AND chemical AND structure AND machine AND learning
TOTAL OF ARTICLES: 15

Three authors have the same number of articles: Gerkin, R.C.; Guan, Y.; Panwar, B.

The country with most publications is the United States

In total, the number of citations until 3/03/2023 is 837.
The year with more publications was 2021, and the graphs for this year are shown below.
5. Choose an article and select the first author, the corresponding author and the group leader.

In this case, the first author would be Achebouche, Rayane. The group leader is Taboureau,
Olivier. The corresponding author is also the group leader in this case.

6. Choose a review and a book published on the subject.

 Review

The are no books about this subject yet. Only articles and reviews.

7. Name 2 technical reports related to the search project

8. Search at least one national patent with reference to the subject of study and 4 international
ones.
9. Inform about the patent: Title, summary, inventors, application number, filing date,
assignment, search field and a referenced patent.
National patent
Patent number: NC2022/0012593
Title: DISPOSITIVO DE AROMATERAPIA ACTIVA MEDIANTE USO DE INTELIGENCIA
ARTIFICIAL
Description: La presente invención se relaciona con un dispositivo de aromaterapia con un
sistema de Inteligencia Artificial que determina mediante imagen o audio las emociones del
usuario y con base en esta emoción determina los aromas a generar en el ambiente sin la
necesidad de que el usuario se desplace a un lugar especializado a tomar la terapia. Con
esta invención se da acceso a que los usuarios puedan tener aromaterapia en cada
momento que lo requieran además de personalizar su resultado según la emoción actual y
la emoción a la cual quiere llegar mediante el uso de Inteligencia Artificial para determinar el
aroma propicio según la emoción actual del usuario y la nueva emoción que se quiere
generar dicha emoción objetivo puede ser determinada por un entorno físico o virtual.
Inventor: Luis Miguel Quevedo Martinez
Filing date: 20 sept. 2022
Search field: Other sectors (Artificial intelligence does not seem to be part of the list)
Patent referenced: No references are included in the information for this patent.

International patents
a. Patent number: WO2023009685 (A1)
Title: SYSTEMS AND METHODS FOR SCENT EXPLORATION
Description: Systems and methods may deliver a personalized fragrance match to
consumers based on fragrance testing, next-generation artificial intelligence, facial
emotional recognition, and olfactory science. The brain's scent receptors may react to
fragrance notes and ingredients, those reactions may be measured, and a custom profile
may be created that pinpoints what the consumer loves to smell and predicts fragrances
that the consumers may love. Using olfactory science, scent may be decoded by learning
the precise receptors activated in the brain by any given fragrance, opening up immense
potential for consumer facing implications. Though individual response to fragrance is
subjective, the receptors being activated are not. Olfactory science enables "digitization"
of fragrance, understanding the "receptor fingerprint" of any given fragrance. Accordingly,
consumers may be matched to fragrances while emphasizing how the consumers want
to feel when wearing the fragrance.
Inventor: LAMB JAMES [US]; GOTTIPATI SOWMYA [US]; MELILLO KARA [US] +
Filing date: 2023-02-02
Patent referenced: US2008131858 (A1)
b. Patent number: US2022414327 (A1)
Title: ARTIFICIAL INTELLIGENCE BASED CLASSIFICATION FOR TASTE AND SMELL
FROM NATURAL LANGUAGE DESCRIPTIONS
Description: Taste and smell classification from multilanguage descriptions can be
performed by extracting, by one or more processors using natural language processing,
a text including one or more words associated with taste and smell perceptions from an
input received from a plurality of users. The input includes multilanguage information
regarding at least one of changes in smell and changes in taste perceived by each of the
plurality of users. Feature vectors are generated for the text extracted from the input
using global vectors, and a distance between the feature vectors and a plurality of
reference descriptors associated with taste and smell is calculated for determining a
similarity between the text and the reference descriptors and creating a training dataset
 based on which a classification model is generated for categorizing the plurality of users
according to the at least one of changes in smell and changes in taste.
Inventor: MEYER ROJAS PABLO [US]; CECCHI GUILLERMO [US]; EYIGOZ ELIF
[US]; NOREL RAQUEL [US] +
Filing date: 2022-12-29
Patent referenced: Does not have any cited documents
c. Patent number: KR102353357 (B1)
Title: SERVER FOR CONTROLLING BAD SMELL FOR BIG DATA ANALYSIS BASED
ON ARTIFICIAL INTELLIGENCE AND METHOD THEREOF
Description: According to the present invention, disclosed are an odor control server
using big data analysis which comprises: a building unit that collects big data to build an
odor analysis model; an analysis unit for generating analysis information by learning the
amount of inputted drug in response to an odor environment or by inputting a similar odor
condition to the odor analysis model; and a remote control unit that generates a control
value based on the analysis information and provides the control value to an odor
reduction device to remotely control an operation of the odor reduction device.
Inventor: KIM JAE HWAN [KR]; KIM YOUNG TAE [KR]; PARK YOUNG KIL [KR] +
Filing date: 2022-01-19
Patent referenced: KR20050047045 (A)
d. Patent number: CN114493550 (A)
Title: Intelligent smell sensor intelligent monitoring system applied to oil depot
Description: The invention discloses an intelligent smell sensor intelligent monitoring
system applied to an oil depot, and the system comprises a safety monitoring system, an
intelligent oil depot data platform, an environment energy monitoring system, an
intelligent warehousing system, and an online monitoring data platform. The AI artificial
intelligence algorithm is combined, management such as identification, judgment, early
warning and disposal of oil depot safety is achieved, the environment-friendly monitoring
system conducts protection of heat insulation and cooling in summer and heat
preservation in winter on an oil tank through energy-saving and environment-friendly
materials, the effect is verified through an intelligent smell sensor, and safety and energy
saving of the oil depot are achieved; the intelligent warehousing system combines
leakage detection, inspection detection, oil temperature detection, external protection
and internal management to carry out online analysis on an existing warehouse. The
invention discloses an intelligent smell sensor intelligent monitoring system applied to an
oil depot, belongs to the technical field of intelligent oil depots, and can monitor the safety
of the oil depot in multiple dimensions.
Inventor: LIN TONGBIN; YU MIAO; ZHANG DAN
Patent referenced: Does not have any cited documents

10. Identify three possible competitors of your product or process, specifying the name, the
country and the differentiating factor.

Competitor 1: Application of artificial intelligence to decode the relationships between smell,

olfactory receptors and small molecules.
Country: France
Differentiating factor: Although they include many types of molecules in their machine
learning method, they do not consider the stereochemistry of the compounds, leaving a vast
number of enantiomeric compounds out of the list, and they are known to present differences
from one to the other.

Competitor 2: Machine learning techniques for code smell detection: A systematic literature
review and meta-analysis
 Country: China
Differentiating factor: In this case, the difference is that they only recognize a certain number
of molecules in their model, but not all of the molecules present an odor to the human nose.
Leaving these molecules out will decrease the prediction level of molecules starting from their
structure.

Competitor 3: Google has built an AI model with a human-like capacity to predict odor.
Country: United States
Differentiating factor: There is still work to do in standardizing the description of smells, since
they have found out it depends on ethnicity, alimentary behavior, age, etc. Their model is still
uncapable of assigning a smell to a molecule, since the description in most of the cases is
subjective.

11. Finally, mention how a supplier, processor and marketer intervene in your product or process.

Since this is a technological process, the role of the supplier would be mixed with the
processor to bring what is needed for the process. First, the space needed to store the data
in the cloud, and computers with the capability of doing all the calculations and associations
for thousand of data inputs. A handbook that includes many substances and their respective
structures, to make sure the information is accurate, and relevant to the investigation.
The role of the marketer would be important here since they would need to bring this product
into a commercial use. Their strategies should be focused on promoting the process to
food/beverage, healthcare, pharmaceutical industries to identify in their list of molecules
which ones would produce an odor with a specific objective. For example, in food, if they
already know a group of molecules produce a specific type of smell, then they could test them
to optimize processes, increase quality, reduce costs, etc.

12. Define the opportunity of your product, development or processes.

The opportunity this process has is the ability to predict the smell of a molecule, and how it
can impact different industries in their utilization, development, innovations, etc. Right now,
the path the industry is taken is towards automatized workflows, and predict models before
wasting materials, time, and equipment, when it could be known before hand if something
would work or not.