Noakhali Scien B.Pharmn Professional nology University ezamination 2022 (Jan-June) Cours 1 Phar 5102 ‘Answer any seven questions, Including qu 1 MCQ on the separate sheet. 10 2. a. How does in-vivo micronucleus assay determine clastogens? : 3 b, Describe aneuploldization. How does aneuploidy play @ vital role in genetic 143 disorders? " Wha happened in Sickel cell anemia? Describe shorty. 3 factors affecting biotransformation? Describe briefly. 4 rome P-450 named? How is cytochrome P-450 involved in phase-I 4 ¢. Write a short note on Entoxification, 's arsenic accumulated in skin, and is it hard to remove? 3 Vihy the half life of lead in bone is larger than in blood? What are the symptoms of | 2#2 mercury poisoning? © “Although iron is a vital nutrient in the human body, it shows corrosive effect inthe 3 GIT". justify the statement. 4 a Why i What are the consequences of toxic injury to kidney? Show the mechanism of 5 tubular obstruction by toxicant with an illustration. What is fatty liver? . Due to intensive chemotherapy, which type of toxicity in blood is observed. Show its 4 mechanism. b. L 2. etine ~1) Risk Assessment) Apoptosis i) Teatogenicty and Ww) Hypersenstivty 4 b. “Hepatic Diseases’ have a great impact on drug metabolism” ~Justify your answer 4 ‘with suitable examples. c. Compare various types of hypersensitivity reactions. 2 Sh eee) On ln b. Give an overview of the steps of poisoning management. 4 Explain why metabolites of paracetamol are more toxic than the metabolites of 2 aspirin, fh 2. How could you repair damaged DNA which is occurred through oxidizing agents? 4 . Define Antidote. Give the mechanism of action of BAL. 3 ¢. Write a short note on Chelating Agents. 3 a Define Saleyiism, Establish a reletionship between aspirin overdose and respiratory = 3 alkalosis. b. What are the factors influencing acetaminophen toxicity. 3 ¢. Give a brief discussion on antibody mediated hypersensitivity reaction.Answer any seven quest 1 b. Noakhall Science and Technology Unive arm Professional Year § TertN rina f ce Department of ph Course Tile: Hospital management, Marksi70, Time: 4h city ‘zammination 2022 Qan-dune) tions, Including question no.t McQ (on the separate sheet) pifferentiate the principle of teamwork from group work, 2 prioritize the big five personality traits to efficient hospital management with proper explanation. Discuss the different levels of organizational behavior in a hospital, 4 Classify hospital waste to smooth away the segregation within the hospital activities, “Being a hospital administrator places more strain " thetsererencs ‘on character than intellect” justify Give an overview of the present hospital waste management system in Bangladesh, Write the epidemiological principle in public health. Make a protocol for Health Need Assessment, Enlist the events of descriptive epidemiology and discuss them. What is the production concept in product management? 2 “Healthcare pricing may follow any strategic option but must be logical and 4 understandable,” analyze the statement. What are the counseling options for the behavioral changes of patients? Discuss, 4 Evaluate the necessary steps need to keep the digestive system healthy & fit. 3 “Knowledge about hospital terminologies helps to provide effective patient care” 4 Justify this statement? Relate the function of the circulatory system with other body systems. 3 ‘Suppose you are a hospital pharmacist in a reputed hospital, develop standard 5 operating procedures (SOPs) for dispensing process. Construct the framework to perform an audit in a hospital. 5 Design a scientific research method with an example. a Illustrate the tools required for data presentation in Biostatistics. Examine the limitation of operation research, : Define material management system. Illustrate the steps involved in an effective 6 material management system in a hospital. down the points that need to be noted before purchasing hospital material. 2 Write dows ‘Summarize the method used to forecast demand.Answer any Seven question: we 2 b. © > Noakhali Science B.Pharm Profession: Course Title: Research Marks al Year 5 Term 1 Final Geottaston goa Dene i ani ition 2022 (Jan-June) arch Methodology, Cource Code: Phar $109 Tine: thes Sesion: 2016-17 including question no. NCQ (Provided in Separate Sheet) *Research is mi 'S Much concerned with the creation of new knowledge’ Justify. 3 Make a comparis : Hake» comparison betwean Research Question and Hypa 3 you think ‘How does social media affect people's behavior?’ Is a standard research 4 question? Give proper logic to support your answer. Write a short note on Fundamental and Applied Research’. 2 ‘Selecting a good research topic involves several steps'-Explain with proper example. 5 Write down the criteria of a good research. 3 As a researcher, which factors should you consider for a research design? 3 Discuss the various types of variables that can interfere with the study results. 4 How is an experimental group different from a Control group? ¥* 3 Outline the steps of sampling design. 4 Discuss different types of Probability and Non-probability Sampling methods. 6 Describe the qualities of a good researcher. 2 Write the difference between the Questionnaire and Schedule. « 4 Mc. Y is a project student. He has both primary data & secondary data for writing his 4 project paper. Which type’s data does he choose for writing his project paper & why? Please explain. Discuss the skill of an interviewer. 2 Compare qualitative data & quantitative data. 4 ‘You are a researcher. Nowadays, suicidal cases are increasing day by day. You want to 4 investigate the reason. Which method do you choose for data collection for your investigation? Please explain. Define peer-review articles, open access journals & predatory Journals. 3 ‘Compare between bibliography & reference. 3 Sodur Rahim and Abdur Karim (Corresponding Author) are students in the Department 4 of Pharmacy, Noakhali that information with a ‘Science and Technology University. Write a title page by using ny title. Define Manuscript evaluation. A Discuss the different sections of an evaluation report. y ott karim and Mr, Alim are Manager. Suddenly production rate decreased. So, 4 rate nen ants an internal evaluation, ond Mr. Alm wants an external assessment, Vinose selection is better, You think. Please justify your word. sNoakhali Science and Technology University &.Pharm Professional Year § Term I Final Examination 2022 (Jan-June) Department of Pharmacy Course Title: Pharmacy Regulatory Affairs, Course Code: Phar 5107 Marks:70, Time: 4 hrs, Session: 2016-17 Answer any seven questions, including question no.t 10 1. McQ ‘Suppose your Pharmaceutical company has launched a new product, a. Its Trade price (TP) is 50 tk, MRP excluding VAT is 58 tk, VAT payable price 4 (vPP) is 57.67 tk, Company VAT 7.5 tk, and retail VAT 1 tk. Calculate the MRP, including VAT for this product. What will be the chemist’s margin here? b, Make an arrow chart showing the approval procedure for this price. 6 3. a. Create a flow chart showing the recipe approval process for a new 5 pharmaceutical product. b. Suppose your company Medica Pharma Bd (Tongi, Gazipur ) has launcheda 5 new drug Ritonavir tablets (white color, film-coated, USP 100 mg) which is an antiretroviral medication to treat HIV/AIDS (DAR No: MPR101112, MLN : MePRit111213 ), 1* batch of it was produced yesterday, and it will be expired feblets after 2 years, ty box eondain a strip of Ie Design a carton for this product Fae ime 50 tK A Concisely describe the principles of the National health policy of Bangladesh. 10 5. 2. Make a plan to promote a pharmaceutical product in the market considering 5 applicable rules and regulations. b. 5 smugglers have been napped with 20 gm of cocaine, 35 gm of pethidine, 5 1.5 kg of opium, 50 liters of alcohol and 4.5 gm of LSD, respectively. What will be the prescribed penalty for them according to the Narcotic act 1990? ~ 2. Differentiate between act and ordinance. 2 b. Discuss the categories of substances listed as drug in Drug Act 1940. 4 © “Any concealment or alteration of quality of a product rendered it as 4 misbranded in Drug Act 1940'- justify. “Drug ordinance 1982 has profound impact on flourishing local pharmaceutical § industries’- justify. Among all objectives of National Drug policy 2005, list the most important 5 three objectives and justify your selections. ‘Advertisement of medicines in strictly prohibited in Drug Ordinance 1982’ - 2+3 why? What are the benefits of such prohibition? Write down the procedures of drug quality assurance in National Drug policy 5 2005. Discuss the power of a drug inspector conferred in Drug Act 1940, 5 ‘Analysis of seized drug samples must be performed with strict protocol in Drug 5 Act 1940" explain.Noakchali Science and Technology University B.Pharm Professional Year 5 Term 1 Final Examination 2022 (Jan-June) Department of Pharmacy, Course Title: Clinical Pharmacy, Course Code: Prar 5202 Marks:70, Time: 4 hws, Session: 2016-17 Answer any seven questions, including question no.3 1 McQ (on the separate sheet) 10 ical progress? x ‘a. How does asthma differ from COPD in respect to thelr pathopinyiola cal progress 5 §Disgaosing and confirming 2 man with breathing ISUe® 26 Oe A ony of patient invelves several investigations, How can we classi these types? Tia : A, a. senator th conations for whic an aia conan scted controled or party > oe Setrolled or uncontrolled? bc Shokethe structure of an asthma review with a flow chart. ; 3 brow anc types of inhalers have been invented to meet up 2 variety of patient 4 requirements ~ analyze the statement, ies like stroke, insomnia, 6 If 2 unipolar patient has any of the mentioned comorbi ‘and hyperthyroidism, what will be the appropriate antidepressant in each case and why? b. Describe the pharmacological basis of depression management. 4 5, a, Write the summary of adverse drug reactions involving the skin. b. Define and mention the sign and symptoms of panic disorder, OCD, and schizophrenia. 2 ¢. Mention the risk factors for developing ADRs. & a. How is creatinine synthesized in our body? 2 b. Evaluate the significance of serum creatinine at different stages of renal impairment. 2 ©. A33-year-old male patient admitted having the following profile with renal impairment: | 3*2 i. Systolic blood pressure: 180 mm-Ha, ref. value: 120 mm-Hg; Il, Serum calcium level 4.4 mg/dL, ref, value: 8.6-10.3 mg/dL; ii, Blood potassium level: 5.9 mmol/L, ref. value: 3.5-5.0 mmol/L. Design your management plan for these conditions. 7. a. An 18-year-old female patient was hospitalized with a nauseated condition. If only 4 ‘solid oral dosage form is available to administer, then justify the best route for such administration and outline the precautions. b. Identify the possible sites for intravenous needle insertion with the parenteral 6 administration process. 25 a If'a drug °X" is needed to be therapeutically monitored, what kind of properties does it require to be confirmed at first? b. How can a drug be therapeutically monitored? 25 The average dosage of oral methotrexate (MTX) for rheumatoid arthritis starts at 5 7.5-10 mg weckly. This is equivalent to 3 or 4 pills taken once a week, which requires therapeutic monitoring. If a patient is prescribed MT%, identify the factors that might interfere with its’ desired therapeutic effect. a. Outline the different characteristics of liver disease. 4 343 b. iad arate A tis pertenes) cavity and itching are common features of acute iver failure. Explain the underlying reason and propose your management plan for each of these medical conditions. a ° ,