‘86 luong nuGe bu 24 hit thay aBi;phy thude vo nhibu you t8 khair tinh rang nude tu >2124h(lugng nude nap vo binh thé) ting dp subtle & edu thin lim cd die nude Ubu & Nguyen nnan __Si8m than ké man tinh: 18 chic xo chin ép vo Bng than va mach mau quan 6g ban _t6 bao éng than kom dap ing vs ADH gwen rhan 8 NGu him thu: do sy xu ign cs ec chit ao Ap sult thm thdu cao godt thin do thn kin: gk 6t ADH ‘Thidu gu: rude dud 6t24h, v8 nigucd,3/24h, v6 nu hod todn150ma/24h thong xvyEo) owen anan da ty xz0ng Bt htm qu du protein wong kong phn tp Jot qua mang ge cbu thn va wot aud Ka nina hp thu 8 than {Be thuon mangle chu thn, protein 8 at i qualch you albumin) “Tén thyong éng than aim ngveng hip tu protein nguyen akan viem chu than, Protein nidu Binh thuéng; nude Ubu Nu nh King co hg cBu,Xét naib cin ads:800-1000 hg Bul al mau dp thru bu mB a (C6 tn co sy mau dong) > navdng to: Hong hing cfu neu _/" gai mau vith: cha a am thay 61 mau pu6e tb Seu tude eg bn angen tog Bt ceo ann ng tai than: nerphon ln thang, xubt hay su thon: wut ruyét tl cong wt su, sl.) do protin vi ce hd phn Khe bi vn al theo thd ca bg 6g thn ng 69 va tinh cht ca poten nigu 66 globulin gut cory ma rude bu, chy chm thay dBi tinh cht hat a nude try rong: thénh phn hd ybu 8 protein, Kid 0 18 BBO Tru nigu teat ry tong 0 thé hg eu, bac edu telah try gu try ms ng dong hat mo tryonbae:do 16 bo dng than bam vonue tiéu bao hoa Tinh chat két dinh nao a6 the yéu té thuan igi: nuée tisu {Qué acid hoe qua kiém Vi khuan nigu: E coli, cau khudn rudt Té bao thurgng bi: té bao bigu mo sinh ra tir 6ng than, bang quang, .. Bach cau niguture mau : san phdm chuyn héa cua protein khi khiy amin tai gan binh thyéng:0,2-0,3911 tng ure mau: n nhitu dam, nh khusn _98p trong trong hyp suy than nang tang én zona, phan én tin trang nbiBm be el ban than khéng Gc nhung phan dnh mic 6 nhi&m doc Hei ching cla co tb do than Khong 820 tha tang ure my cae sén phBm chia nto kde: creatinin, aod ure nuyén nhanthye sp sty nniém de indolphenol acid, mdi phosphasuiphat 1a sin phdm chuydn hoa ea ereatin phosphate & co Tang rao oe bin thudng05-1.2mo'd mau rnguyn nha: suy than ep, man tinh, thao dung, suy timhoal theo van, nhl mau co tim ‘Than tham gl lt cdn bing Kibm toan Toan mau kiém,nang dn dén nhiém toan mét bo“Thuting gp 6 46 tu6i 6-10 ti NNguyén nha: thuting gp sau nim LC tan méu beta nhémn A ca che bénh sinh him tring duting hd hip tn do ty 12 do tyb 49,55,57,60 him tring ng viém cfu thn cp do ch mién dich viém mao mach cBu thén (nding n hon), viém mao mgch tosn than _thiém lién Bu nhém A od thé tao IgG va IgM két hop vb Kring nguyén protein M cia lin cu vim mang dy hat héa bé thé hat héa BC gay vigm 1h thdng déng mau PHMD lui hinh dn cu thin Ibng dong va gay vm | Prine day oo mang day tao thanh hinh 9 {én thuong lan réng sim Sioc ait tng tinh thm mang ige__ protein nigu, dng cu nigu thigu méu 6 thin (déng méu) tng tit renin lam tng huyét 69 viém mao mach ngoal vi gy tng tinh thm(phi), co mach tng site cn ngoal vi dc 18, VK thay déi t# bao cu thn than ty khng nguyén co thé tao khang thé gy viém thn ty mign bigu hign: phi, dit, di mau, tng huyét dp XN nude tiéu: protein, hing cu, tr. XN méusure, creatinin mau ting King thé khéng ién eu, t8 bao cBu thin 6 thé toa phiin glam phic hgp midn dich chia 196,C3,C5, properdin vide thd ty mig XN mign dich:ni ching lam sang va sinh ha, xuat hin khi cBu thén bi tén thucng i céc bénh I khc nhau {3c trung bdi phi, dai it, protein nigu, albumin mau giém, r6ilogn lipid mau, dai me HCTH nguyén phat: bén i cu thén nguyén phat aguyén aban. thanh phiin tao dién tich am ola mang day, co kéo mat chan t8 bio biéu mé am thay 46) kich thud loc albumin at di qua mang Igc lim gidm albumin trong huyét tudng (goal ra cbn ob céc protein khic) hhoat hoa hg RAA Co ché Gidim 4p suat keo ‘idm thé tich bénh sinh gy phu tun hoan tng chifc nng than kinh giao cam ting téng hp lipoprotein & gan lipid mau tng do giém i héa do, mat lipid dich loc Hing dong ma 6 lang 6ng cenzym di héa qua duting nuéc tiéu ng cao md trong nut ta biéu hién:dai it, phi todn than,nuc tiéu c6 bot ra XN nuiéc tiéu: protein nigu, try m@, tinh thé cholesterol, t€ bo mé hinh bu duc im sing rméualbumin méu gidm, anipha 2, beta globuin gidm,ting lipid, cholesterol Hau qua: suy than ep, nhigm khudn,.Glam thd tich mau truée than gidm cung lugng tim tuthuyét ap nang, kéo da mach méu [én tai than do cau than nguyén nan. viém than ké cp sau than: te edp dung dn nigu do si, u cj mre 02.98 dong mau an than ap wo tly : ach inh mao loc clu tng ap ly thay tinh trong bao Bowman ne than co that mach than, gidm dong mau & vé than J | than gidm co ché bénh sinh sung phéng té bao ngi m6, bisu mé c6 chan giam tinh thém mang loc tde éng than:éo sy xudt hign ela cée ty, tn thé, khuéch tan nguge tré Iai ctia dich Ie do éng than tn thuong tang ap lye eva t8 chibc ké chén ép vao éng thantn thuving ¢ cu thin, mach thin. nephron tén thucing ning mat chifc ning sinh i chile ning thin dugc thy hign bal ce nephron nguyén ven cén lal nephron bi tén thutng qua niéu, céc nephron ting eying hoat ding tn thuving qué nhiéu khéng duy ti dude hang s6 ni mdi uit hin ri loan vé twin hodn, hé hap, tiéu héa, than kinh 0 che bénh sinh cdc r6i loan chinh‘gam macige __9l8m 8 khBng hbi phue ehuthen ceang gidm suy than cang nang sglai dogn Gu nati ting mite Igc cu thén<20mi/phut: natri mau giam do gidm tai hp thu Cr) lai doan dau K+ mau chua tang do 66 tang tét adosterol tang thai tir tithe thu ‘ng & gia doan dau do: tng thu np kal, dha protein, tan mau, Hi: ph mau gidm do khong tha tir duge He, dy tr kiém gi, si nhiu: do giém hap thu gay da nigu thém thu aim ting hap chét chuyén héa vitamin D ina J giim hép tu clei rut giim cle mu, ting phosphate méu ip tuyén cd gidp tang iép PTH lam tang huy dong calel ty xuong v8o mau yéu t6 lam tang cubng can al: té bao xuong kém dap Ung. Jong xaromg: do cham qué trinh tao xuong, kkniém khuyét trong qua trinh mudi khong héa cia xuong ‘én chu chuyén xurong cao thong vigm xyong x0" xuomg Joan dung xwong shud 007 yn TO ti cb rie xoxudt hign s6m va ting dn khi chire nding than suy giam Ur dong chat dc tre ché erythopoietin idm tiéterythopoietin thigu nguyén liu tao mau tribu mau n nguyén nha tang hoat déng RAA idm kind nding bai xudt nat, thisa dich ngoai bao, tang thé tich tuan hoan ‘uy gidm chic nang t& bao ndi mac, idm dép Ging vs cde yéu t6 gian mach tng hoat tinh eta hd giao cam ngodi ra:d6c 6, erythropoietin. ting huyét ap ‘ng: r6i loan kinh nguy@t, gidm thy thai, ram: gidm testosteol gay ri foan tinh due, gidm san xuat tinh trang gidm calci, natri gay chudt nit noi tiét (Gc biét sinh dyc) tsb loan ke ‘ybu cor do lng dong call than kinnh co_/” viem than kinh ngoai vi do King dong cc phan tir trong lvgng trung binh