Scribd Logo
Upload

Welcome to Scribd!

  • Abstract 16136122

    Uploaded by

    Clory Dell'aquila
    8 views1 page
    1. Researchers found that extra-virgin olive oil contains oleocanthal, a compound that induces a stinging sensation similar to ibuprofen. 2. Oleocanthal was shown to act as a natural anti-inflammatory compound with potency and effects similar to ibuprofen, despite being structurally dissimilar. 3. Both oleocanthal and ibuprofen inhibit the same cyclooxygenase enzymes involved in prostaglandin biosynthesis.

    Original Description:

    Original Title

    abstract-16136122

    Copyright

    © © All Rights Reserved

    Available Formats

    TXT, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    1. Researchers found that extra-virgin olive oil contains oleocanthal, a compound that induces a stinging sensation similar to ibuprofen. 2. Oleocanthal was shown to act as a natural anti-inflammatory compound with potency and effects similar to ibuprofen, despite being structurally dissimilar. 3. Both oleocanthal and ibuprofen inhibit the same cyclooxygenase enzymes involved in prostaglandin biosynthesis.

    Copyright:

    © All Rights Reserved
    Download as TXT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    8 views1 page

    Abstract 16136122

    Uploaded by

    Clory Dell'aquila
    1. Researchers found that extra-virgin olive oil contains oleocanthal, a compound that induces a stinging sensation similar to ibuprofen. 2. Oleocanthal was shown to act as a natural anti-inflammatory compound with potency and effects similar to ibuprofen, despite being structurally dissimilar. 3. Both oleocanthal and ibuprofen inhibit the same cyclooxygenase enzymes involved in prostaglandin biosynthesis.

    Copyright:

    © All Rights Reserved
    Download as TXT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    1. Nature. 2005 Sep 1;437(7055):45-6. doi: 10.1038/437045a.

    Phytochemistry: ibuprofen-like activity in extra-virgin olive oil.

    Beauchamp GK(1), Keast RS, Morel D, Lin J, Pika J, Han Q, Lee CH, Smith AB,
    Breslin PA.

    Author information:
    (1)Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104, USA.

    Newly pressed extra-virgin olive oil contains oleocanthal--a compound whose


    pungency induces a strong stinging sensation in the throat, not unlike that
    caused by solutions of the non-steroidal anti-inflammatory drug ibuprofen. We
    show here that this similar perception seems to be an indicator of a shared
    pharmacological activity, with oleocanthal acting as a natural anti-inflammatory
    compound that has a potency and profile strikingly similar to that of ibuprofen.
    Although structurally dissimilar, both these molecules inhibit the same
    cyclooxygenase enzymes in the prostaglandin-biosynthesis pathway.

    DOI: 10.1038/437045a
    PMID: 16136122 [Indexed for MEDLINE]

    You might also like