Scribd Logo
Upload

Welcome to Scribd!

  • Handling, Rute, Perhitungan

    Uploaded by

    Maria Aya
    1 views5 pages

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    1 views5 pages

    Handling, Rute, Perhitungan

    Uploaded by

    Maria Aya

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 5

    No Kegiatan Dokumentasi

    1. Pemberian obat Intravena

    2. Pemberian obat Intramuscular

    3. Pemberian obat Intraperitonial

    4. Pemberian obat Subkutan

    5. Pemberian obat Per Oral

    Pemberian obat 5 rute


    Handling
    No. Kegiatan Dokumentasi
    1. Pengambilan hewan percobaan
    dengan cara pegang ekor hewan
    percobaan ( mencit)

    2. Pegang bagian belakang leher


    dengan ibu jari dan telunjuk, serta
    tenangkan hewan percobaan
    (mencit)

    3. Penimbangan hewan percobaan


    (mencit)
    1. Na-CMC 0,5% ( control negative)
    Na-CMC 0,5 mg dalam 100 ml
    - Intravena
    VAO = 1/2 x 0,5 ml = 0,25 ml
    Volume pemberian :
    1. Mencit 25 gram = 25 gram/35 gram x 0,25 ml = 0,17 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,25 ml = 0,20 ml
    3. Mencit 23 gram = 23 gram/35 gram x 0,25 ml = 0,16 ml
    - Intra Muscular
    VAO = ½ x 0,05 ml = 0,025 ml
    Volume pemberian :
    1. Mencit 25 gram= 25 gram/35 gram x 0,025 ml = 0,017 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,025 ml = 0,020 ml
    3. Mencit 23 gram = 23 gram/35 gram x 0,025 ml = 0,016 ml
    - Intra Peritonial
    VAO = ½ x 1 ml = 0,5 ml
    Volume pemberian :
    1. Mencit 25 gram= 25 gram/35 gram x 0,5 ml = 0,35 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,5 ml = 0,41 ml
    3. Mencit 23 gram = 23 gram/35 gram x 0,5 ml = 0,32 ml
    - Subkutan
    VAO = ½ x 1 ml = 0,5 ml
    Volume pemberian :
    4. Mencit 25 gram= 25 gram/35 gram x 0,5 ml = 0,35 ml
    5. Mencit 29 gram = 29 gram/35 gram x 0,5 ml = 0,41 ml
    6. Mencit 23 gram = 23 gram/35 gram x 0,5 ml = 0,32 ml
    - Per Oral
    VAO = ½ x 1 ml = 0,5 ml
    Volume pemberian :
    1. Mencit 25 gram= 25 gram/35 gram x 0,5 ml = 0,35 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,5 ml = 0,41 ml
    3. Mencit 23 gram = 23 gram/35 gram x 0,5 ml = 0,32 ml

    2. Paracetamol 500 mg/60 kgBB


    Faktor konversi = 0,0026 (Mencit)
    Mencit 20 gram = 500 mg x 0,0026 = 1,3 mg
    Mencit 35 gram = 35 gram/20 gram x 1,3 mg = 2,275 mg
    - Intravena
    VAO = 1/2 x 0,5 ml = 0,25 ml
    Larutan stok = 10/0,25 ml x 2,275 mg = 91 mg
    Volume pemberian :
    1. Mencit 30 gram = 30 gram/35 gram x 0,25 ml = 0,2 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,25 ml = 0,2 ml
    3. Mencit 28 gram = 28 gram/35 gram x 0,25 ml = 0,2 ml
    - Intra Muscular
    VAO = 1/2 x 0,05 ml = 0,025 ml
    Larutan stok = 10/0,025 ml x 2,275 mg = 910 mg
    Volume pemberian :
    1. Mencit 30 gram = 30 gram/35 gram x 0,025 ml = 0,02 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,025 ml = 0,02 ml
    3. Mencit 28 gram = 28 gram/35 gram x 0,025 ml = 0,02 ml
    - Intra Peritonial
    VAO = 1/2 x 1 ml = 0,5 ml
    Larutan stok = 10/0,5 ml x 2,275 mg = 45,5 mg
    Volume pemberian :
    1. Mencit 30 gram = 30 gram/35 gram x 0,5 ml = 0,4 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,5 ml = 0,4 ml
    3. Mencit 28 gram = 28 gram/35 gram x 0,5 ml = 0,4 ml
    - Subkutan
    VAO = 1/2 x 1 ml = 0,5 ml
    Larutan stok = 10/0,5 ml x 2,275 mg = 45,5 mg
    Volume pemberian :
    1. Mencit 30 gram = 30 gram/35 gram x 0,5 ml = 0,4 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,5 ml = 0,4 ml
    3. Mencit 28 gram = 28 gram/35 gram x 0,5 ml = 0,4 ml
    - Per Oral
    VAO = 1/2 x 1 ml = 0,5 ml
    Larutan stok = 10/0,5 ml x 2,275 mg = 45,5 mg
    Volume pemberian :
    1. Mencit 30 gram = 30 gram/35 gram x 0,5 ml = 0,4 ml
    2. Mencit 29 gram = 29 gram/35 gram x 0,5 ml = 0,4 ml
    3. Mencit 28 gram = 28 gram/35 gram x 0,5 ml = 0,4 ml

    3. Ibuprofen 400 mg/70kgBB


    Faktor konversi = 0,0026 (Mencit)
    Mencit 20 gram = 400 mg x 0,0026 = 1,04 mg
    Mencit 35 gram = 35 gram/20 gram x 1,04 mg = 1,82 mg
    - Intravena
    VAO = 1/2 x 0,5 ml = 0,25 ml
    Larutan stok = 10/0,25 ml x 1,82 mg = 72,8 mg
    Volume pemberian :
    1. Mencit 27 gram = 27 gram/35 gram x 0,25 ml = 0,1 ml
    2. Mencit 28 gram = 28 gram/35 gram x 0,25 ml = 0,1 ml
    3. Mencit 39 gram = 39 gram/35 gram x 0,25 ml = 0,1 ml
    - Intra Muscular
    Larutan stok = 10/0,025 ml x 1,82 mg = 728 mg
    Volume pemberian :
    1. Mencit 27 gram = 27 gram/35 gram x 0,025 ml = 0,01 ml
    2. Mencit 28 gram = 28 gram/35 gram x 0,025 ml = 0,02 ml
    3. Mencit 39 gram = 39 gram/35 gram x 0,025 ml = 0,02 ml
    - Intra Peritonial
    Larutan stok = 10/0,5 ml x 1,82 mg = 36,4 mg
    Volume pemberian :
    1. Mencit 27 gram = 27 gram/35 gram x 0,5 ml = 0,3 ml
    2. Mencit 28 gram = 28 gram/35 gram x 0,5 ml = 0,4 ml
    3. Mencit 39 gram = 39 gram/35 gram x 0,5 ml = 0,5 ml
    - Subkutan
    Larutan stok = 10/0,5 ml x 1,82 mg = 36,4 mg
    Volume pemberian :
    1. Mencit 27 gram = 27 gram/35 gram x 0,5 ml = 0,3 ml
    2. Mencit 28 gram = 28 gram/35 gram x 0,5 ml = 0,4 ml
    3. Mencit 39 gram = 39 gram/35 gram x 0,5 ml = 0,5 ml
    - Per Oral
    Larutan stok = 10/0,5 ml x 1,82 mg = 36,4 mg
    Volume pemberian :
    1. Mencit 27 gram = 27 gram/35 gram x 0,5 ml = 0,3 ml
    2. Mencit 28 gram = 28 gram/35 gram x 0,5 ml = 0,4 ml
    3. Mencit 39 gram = 39 gram/35 gram x 0,5 ml = 0,5 ml

    You might also like