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Psychopathology 19: 244-252 (1986) 0254-4962/86/OI95-0244S2.75/0

First-Rank Symptoms and Bleuler’s Basic Symptoms


New Results in Applying the Polydiagnostic Approach

P. Bernera, H. Katschnig'0, G. Lenza


“Psychiatric Clinic, University of Vienna and
bDepartment of Social Psychiatry, Psychiatric Clinic, University of Vienna, Austria

Abstract. By comparing six different operational diagnostic systems (International Classi­


fication of Diseases, Diagnostic and Statistical Manual; 3rd ed., Research Diagnostic Crite­
ria, St. Louis criteria, Taylor criteria and Vienna Research Criteria), the data presented in
this paper illustrate how attribution to various categories of functional psychoses varies
according to the applied algorithms. Bleuler’s basic symptoms are obviously considered by
all of the compared systems to be more significant for attribution to schizophrenia than
first-rank symptoms.

Introduction lates with regard to the differentiation be­


tween schizophrenia and affective disorders
With the exception of French psychiatry, that the presence of ‘schizophrenic’ symp­
the main efforts to divide functional psy­ toms deprives manic-depressive features of
choses into subgroups were centered until their diagnostic value. Subsequently, the def­
recently on the diagnosis of schizophrenia. inition of the phenomena to be considered as
Two major reasons may be held responsible schizophrenic became a preoccupation in
for this fact: The first is the incorporation of which, after Kraepelin, two trends pre­
Kraepelin's paraphrenias into his concept of vailed.
paranoid schizophrenia, which was done be­ The most eminent representative of the
cause catamnestic studies demonstrated that first of these diagnostic approaches to
paraphrenic patients may eventually de­ schizophrenia is E. Bleuler [6], who aban­
velop residual deficiency states [19]. Thus doned the illness course as diagnostic crite­
for the functional psychoses, the concept of a rion and established two symptom hierar­
simple dichotomy distinguishing only be­ chies. The theoretical, etiopathogenetic dis­
tween schizophrenia and manic-depressive tinction between primary symptoms, which
illness became prevalent. The second reason are directly related to the illness process and
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was the explicit or implicit acceptance of are thus autochthonous, and secondary
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Jaspers’ hierarchical principle, which stipu­ symptoms, which represent reactions to the
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First-Rank Symptoms and Blculcr’s Basic Symptoms 245

illness process and thus are psychologically symptoms’ may occur in affective disorders
understandable, must not be confused with as well; this led some of them to plead for a
the clinical distinction between basic and reversal of Jaspers’ hierarchical principle.
accessory symptoms appearing in schizo­ The doubts expressed in view of the specific­
phrenic illness. Basic symptoms are consid­ ity of ‘schizophrenic symptoms’ concerned
ered as signs of special value for the diagno­ most frequently Schneider’s first-rank symp­
sis. Some of them belong the the primary, toms (FRS), but it might be argued, espe­
some to the secondary symptoms. Thus, cially in consideration of Janzarik’s [ 15] con­
Bleuler’s diagnostic rules are not really based cept of the ’structural dynamic coherency’,
solely on his theory of the illness process, but that at least a part of Bleuler’s basic symp­
they are strongly ‘theory-oriented’. The other toms may arise not only in schizophrenic but
attempt to define schizophrenia phenome­ also in rapidly alternating manic-depressive
nologically is a pragmatical one, introduced mixed states [4, 9, 21, 22],
by K. Schneider [26] when establishing his More recently formulated diagnostic
list of ‘first-’ and ‘second-rank’ symptoms. tools attempt to counterbalance the fore-
These symptoms were arbitrarily chosen in mentioned shortcomings of the classical
order to draw a clear line between schizo­ bleulerian and Schneiderian diagnostics
phrenic and manic-depressive disorders; mainly through two precedures, namely re­
only those symptoms were included which stricting some well-definable schizophrenic
presented no undue difficulty for conceptual symptoms and introducing criteria for exclu­
comprehension and clinical recognition. sion. Among the latter figure essentially
Both Bleuler’s and Schneider’s diagnostic manic-depressive symptoms, criteria of ill­
procedures have their specific deficiencies: ness course and symptomatological or other
Bleulcr’s criteria for schizophrenia have empirical indicators of good prognosis de­
never been adequately operationalized [7, rived mainly from Scandinavian studies on
13], and Schneider’s neglect of any underly­ ‘schizophreniform’, ‘psychogenic,’ or ‘reac­
ing theoretical concept led many searchers to tive psychoses’. Only a few of these modern
question their heuristic value. Furthermore, diagnostic algorithms base their symptoma­
the adherence to Jasper’s hierarchical princi­ tological elements solely on some of
ple was increasingly considered as a defi­ Schneider’s (e.g. the CATEGO system) or
ciency of both systems: as early as 1933, some of Bleuler’s schizophrenic symptoms
Kasanin suggested that patients exhibiting (e.g. the Vienna Research Criteria, VRC);
schizophrenic as well as affective features most of them are ‘mixed’, i.e. they contain a
may belong to an independent group called combination of selected bleulerian or Schnei­
‘schizoaffective psychoses’. Thus, he ques­ derian criteria. When choosing one of these
tioned at the same time both Jaspers’ hierar­ ‘mixed’ diagnostic systems, the user is rarely
chical principle and the dichotomy of func­ aware of the real importance it attributes -
tional psychoses. Later, especially during the through its operational rules - to FRS or to
last decade, numerous psychiatrists [re­ Bleuler’s basic symptoms for the establish­
ported in ref. 3, 18, 23, 24] voiced, on the ment of the diagnosis of schizophrenia. The
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grounds of empirical data or theoretical con­ application of the polydiagnostic approach


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siderations, the opinion that ‘schizophrenic [16], which consists in applying a whole set
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246 Berner/Katschnig/Lenz

of different diagnostic criteria to the same Table I. Frequency of FRS in 97 first-admitted


sample of patients, enables us to elucidate schizophrenic patients (ICD 295)
this problem. n %
The following data are taken from a re­
search project on functional psychoses, At least one FRS 84 86.6
based on 200 first-admission patients to the
Psychiatric Clinic and to the Psychiatric Delusional perceptions 48 49.5
Hospital of Vienna with an ICD diagnosis of Made volition, made affect and 38 39.2
295, 296, 297 or 298. The patients were made impulses
rated with an expanded version of the
Present State Examination [27], and a series Thought withdrawal and thought 29 29.9
of diagnostic criteria for schizophrenia, schi­ insertion
zoaffective disorder and affective disorder Voices commenting 27 27.8
were applied to them. In order to demon­
strate the differences of various diagnostic Voices arguing 26 26.8
systems with regard to the weight they assign
to FRS and basic symptoms, we herewith Thought broadcasting 20 20.6
present the findings obtained with five Somatic passivity experiences 17 17.5
'mixed’) algorithms (Taylor, RDC, ICD-9,
St. Louis, DSM-III). These results are com­ Audible thoughts 12 12.4
pared with those gathered when applying the
VRC, which do not contain FRS and are
exclusively based on certain selected basic
symptoms. This comparison permits some Table II. Frequency of Bleuler’s basic symp-
toms in 97 first-admitted schizophrenic patients
considerations regarding the concordance
(ICD 295)
between FRS and the basic symptoms of
Bleuler. n %

At least one of Blculer’s basic 87 89.7


symptoms
Prevalence of FRS and Basic Symptoms
in ICD Schizophrenic Psychoses Disturbances of affect 66 68

The prevalence of FRS in patients diag­ Disturbances of volition and 45 46.4


nosed as schizophrenic according to various behavior
different diagnostic systems differs consider­
Disturbances of the subjective 45 46.4
ably from one study to another. Mellor [20] experience of self
found that 72% of his schizophrenic patients
had one or more FRS. Prevalence was some­ Formal thought disorder 39 40.2
what lower in the international pilot study of
Autism 27 27.8
schizophrenia with 57% [11]; Huber et al.
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[14] found a prevalence of 77.5% in his Ambivalence 18 18.6


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patients, Bland and Orn [5] one of 88%. The


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First-Rank Symptoms and Bleulcr’s Basic Symptoms 247

distribution of FRS in our sample corre­ contains not only ‘affective blunting’ but
sponds roughly to the frequency given by also other disturbances especially ‘parathy­
Bland and Orn. Table I demonstrates, in ac­ mia’ (inappropriate affect), which quite fre­
cordance with findings of Koehler et al. [ 17] quently occur in rapidly changing manic-
and Bland and Orn [5], that the most fre­ depressive mixed states as well.
quently encountered FRS are ‘delusional
perceptions’. They are closely followed by
‘made volition, affect, or impulses’ whilst all Discriminative Ability Attributed by
other FRS occur less often. Various Diagnostic Systems to FRS and
Although Bleuler’s basic symptoms are Basic Symptoms
contained in several diagnostic systems and
research criteria, much less is written about The collaborating investigators of the In­
them compared with the many papers dis­ ternational Pilot Study of Schizophrenia
cussing various aspects of Schneider’s FRS. [28], using data from nine participating
This might be due to the above-mentioned countries and putting patients diagnosed as
fact that for many of them a satisfactory schizophrenic together with those suffering
operational definition has not yet been for­ from paranoid psychoses, found that most
mulated, so that they cannot be diagnosed FRS were highly disciminating: For exam­
with sufficient reliability [4, 7], In our sam­ ple, a patient who hallucinated voices dis­
ple the distribution of Bleuler’s basic symp­ cussing him had a 0.95 probability of receiv­
toms clearly shows the relative importance ing a diagnosis of schizophrenic or paranoid
of the ‘disturbances of affect’ (table II). Now­ psychosis. A patient who experienced his
adays, these symptoms can certainly be elic­ thoughts as being broadcast had a 0.97 prob­
ited much more reliabley with recently de­ ability of receiving these two diagnoses. Sim­
veloped instruments, e.g. the ‘scale for the ilarly, thought insertion, thought withdraw­
assessment of negative symptoms’ of An- al, and delusions of control each had a prob­
dreasen [1], But when discussing the signifi­ ability of 0.93-0.97 of being associated with
cance o f ‘disturbances of affect’ for the diag­ a diagnosis of schizophrenia or paranoid
noses of schizophrenia, it should be kept in psychosis. Therefore, most of the FRS taken
mind that this symptomatological category individually were found by the participants
of the study to be strong diagnostic indica­
tors, although they did not occur exclusively
in schizophenia. Table III shows that the dis­
Table III. Probability of receiving different diag­ criminative ability attributed to FRS by the
noses of schizophrenia for patients who have experi­
diagnostic systems included in our study in
enced at last one FRS (n = 121)
in general much lower and that it differs also
Taylor criteria for schizophrenia (n = 96) 0.74 - sometimes considerably - from one algo­
RCD schizophrenia (n = 67) 0.54 rithm to the other.
1CD schizophrenia (n = 64) 0.46 The first findings can be explained by the
St. Louis schizophrenia (n = 44) 0.39
fact that all of the ‘mixed’ diagnostic systems
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DSM-III schizophrenia disorder (n = 49) 0.36


presented in table III contain affective fea­
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VRC schizophrenia (n = 40) 0.30


tures as exclusion criteria (the ICD-9 implic­
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248 Berner/Katschnig/Lenz

itly, because the schizoaffective subgroup Tabic IV. Probability of receiving different diag­
has been withdrawn, the others explicitly). noses of schizophrenia for patients who have at least
one of Bleuler’s basic symptoms (n = 91)
The differences between the various systems
must be located in their specific algorithmic Taylor criteria for schizophrenia (n = 96) 0.85
rules. Thus it is not surprising that Taylor’s ICD schizophrenia 0.69
criteria, which consider the presence of at (295 without 295.7, n = 64)
least one FRS as sufficient for inclusion and RCD schizophrenia (n = 67) 0.59
DSM-III schizophrenic disorder (n = 49) 0.45
use (apart from clouded consciousness and VRC schizophrenia (n = 40) 0.44
somatic disturbance) only affective disorders St. Louis criteria for schizophrenia (n = 44) 0.42
as excluding features, attribute the highest
discriminative ability of all compared sys­
tems to FRS. The very low probability rate
of the St. Louis criteria and DSM-III must be basic symptoms to be included in Taylor’s
mainly attributed to the requirement of an schizophrenia. The somewhat lower but still
illness duration of at least 6 months. As relatively high probability rate of ICD-9 and
expected, the RDC, which have reduced this RDC reflects their linkage to Bleuler’s con­
time limit to 2 weeks, offer a higher proba­ cept of schizophrenia, whilst the low proba­
bility for patients who have experienced at bility found when applying DSM-III and the
least one FRS to be classified as schizo­ St. Louis criteria has again to be attributed
phrenics; this probability remains, however, to the required illness duration. Since the
much lower than that encountered when us­ VRC consider only well-defined formal
ing Taylor’s criteria. This may be attributed thought disorders as features permitting the
to the fact that the RDC require at least two diagnoses of schizophrenia, the probability
of their symptomatological inclusion criteria of receiving this diagnosis when exhibiting at
for making the diagnosis whilst Taylor is sat­ least one basic symptom is, as expected,
isfied with one single FRS. The relatively low.
low probability rate of ICD-9 reflects its de­ In general, it may be deduced from tables
pendence on Bleuler’s concept. The lowest III, IV that there is a high probability for
probability is found when applying the VRC patients exhibiting at least one FRS or one
(which also exclude cases fulfilling the crite­ basic symptom to receive the diagnosis of
ria for schizophrenia and affective disorders schizophrenia if the diagnostic algorithm
by diagnosing them as a ‘schizoaffective syn­ builds symptomatologically on these symp­
drome’). This is certainly due to the fact that toms only (which applies to Taylor’s crite­
they are not based upon FRS. ria). The probability is low, if (as is the case
Table IV demonstrates the discriminative for all the other ‘mixed’ systems presented)
ability attributed to Bleuler’s basic symp­ second-rank and accessory symptoms are
toms: Explanations similar to those exposed also included in the algorithm and if more
with reference to FRS may also apply to the than one FRS or basic symptom is required.
differences shown in table IV. The inclusion The introduction of a time limit further low­
of formal thought disorders and affective ers the discriminative ability attributed to
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blunting in Taylor’s criteria explains the in­ FRS and basic symptoms. This discrimina­
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creased probability of patients with Bleuler’s tive ability is, of course, also considered to
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First-Rank Symptoms and Bleuler’s Basic Symptoms 249

Table V. Probability of receiving different diagnoses of schizophrenia for patients who experienced differ­
ent FRS [26]

Taylor St. Louis RDC VRC DSM-III ICD

Made volition, made affect and 0.73 0.35 0.48 0.39 0.33 0.50
made impulses
Delusional perceptions 0.71 0.33 0.49 0.23 0.35 0.40
Voices commenting 0.90 0.73 0.87 0.53 0.63 0.87
Voices arguing 0.86 0.46 0.86 0.41 0.51 0.57
Thought withdrawal and 0.82 0.45 0.67 0.61 0.52 0.61
thought insertion
Somatic passivity experiences 0.90 0.52 0.76 0.43 0.52 0.71
Thought broadcasting 0.95 0.45 0.64 0.50 0.50 0.64
Audible thoughts 0.85 0.54 0.69 0.54 0.54 0.69

be low if the algorithm is exclusively built on the exception of the criteria requesting a 6-
a narrow seletion of certain symptoms (as is month duration of the illness (St. Louis,
the case for the VRC). DSM-11I), the item ‘thought withdrawal and
thought insertions’ also shows a relatively
high probability rate. In particular the fact
Discriminative Ability Attributed to that this applies also to patients diagnosed as
Single FRS or Basic Symptoms schizophrenic by VRC suggest that there
might be a linkage between observed formal
Table V compares the probabilities of re­ thought disorders and the subjective experi­
ceiving the diagnosis of schizophrenia for ence of thought withdrawal or thought inser­
each FRS. With the exception of Taylor’s tion.
criteria (which impute an equal weight to Table VI shows that some of Bleuler’s
each FRS) the compared systems do not basic symptoms have an important discrimi­
attribute a high discriminative value to most native ability in all of the compared systems:
of the FRS. The symptom ‘voices comment­ the high probability of receiving a diagnosis
ing’ is, however, loaded with a relatively high of schizophrenia when formal thought disor­
probability in all classifications - a finding ders arc present is indeed very impressive.
which is in line with Bland and Orn’s [5] out­ The somewhat lower probability for the St.
come study, where the authors found ‘voices Louis criteria and DSM-III is again due to
commenting’ negatively correlated on all the necessity of a 6-month illness duration.
outcome measures, which means that this With the exception of the Viennese criteria,
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symptom is a strong predictor for bad out­ ‘autism’ is also loaded with a high probabil­
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come. Furthermore, it is striking that, with ity in all systems.


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250 Berner/Katschnig/Lenz

Table VI. Probability of receiving different diagnoses of schizophrenia for patients with different ‘basic
symptoms’ according to Bleuler

Taylor St. Louis RDC VRC DSM-III 1CD

Disturbances of affect 0.94 0.48 0.62 0.51 0.54 0.75


Formal thought disorder 0.95 0.69 0.90 1.00 0.69 0.90
Disturbances of volition and behavior 0.87 0.45 0.57 0.36 0.49 0.77
Autism 0.97 0.76 0.83 0.55 0.72 0.90
Disturbances of the subjective 0.87 0.44 0.69 0.51 0.44 0.69
experience of self
Ambivalence 0.77 0.39 0.56 0.39 0.39 0.61

Table VII. Frequency (%) of at least one FRS in Table VIII. Frequency (%) of at least one of Bleu-
various diagnostic criteria ler’s basic symptoms in various diagnostic criteria

RDC schizophrenia 97.0 VRC schizophrenic axial syndrome 100.0


St. Louis schizophrenia 93.2 ICD 295 89.7
Taylor schizophrenia 92.7 St. Louis schizophrenia 86.4
RDC schizoaffective, manic type 92.0 DSM-III schizophrenic disorder 83.7
VRC schizophrenic axial syndrome 90.0 RDC schizophrenia 80.6
DSM-III schizophrenic disorders 87.8 Taylor schizophrenia 80.2
RDC schizoaffective, depressive type 87.5 RDC schizoaffective, manic type 76.0
ICD 295 86.6 RDC schizoaffective, depressive type 68.8
Taylor mania 50.0 VRC cyclothymic axial syndrome 25.6
VRC cyclothymic axial syndrome 43.0 Taylor mania 18.2
St. Louis mania 33.3 RDC mania 6.5
RDC mania 32.3 Taylor depression 5.4
Taylor depression 16.1 St. Louis mania 3.7
ICD 296 13.0 St. Louis depression 2.0
St. Louis depression 6.1 RDC major depressive disorder 0
RDC major depressive disorder 4.3 ICD 296 0

Occurrence of FRS and Basic Symptoms disorders [10]. In their comprehensive re­
in Disorders Not Diagnosed as view, Pope and Lipinski [23] conclude that a
Schizophrenic considerable amount of patients diagnosed
as good prognosis schizophrenia really be­
As already mentioned in the introduction long to the affective disorders. In order to
several studies have indicated that FRS not further elucidate this assumption, we com­
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only occur in schizophrenia but also in man­ pared the frequency of FRS and basic symp­
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ic-depressive illness and even in neurotic toms in patients attributed by the compared
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First-Rank Symptoms and Bleuler’s Basic Symptoms 251

systems to schizophrenic, schizoaffective ing to Janzarik [15], from a ‘dynamic re­


and affective disorders. These findings are striction’.
presented in tables VII, VIII. Table VII By comparing six different operational
shows the percentage of patients exhibiting diagnostic systems, the data presented in this
at least one FRS for each category. It is paper illustrate how attribution to various
noteworthy that there are still many pa­ categories of functional psychoses varies ac­
tients whose symptomatology includes FRS, cording to the applied algorithms. Bleuler’s
even when they fulfill the conditions for basic symptoms are obviously considered by
attribution to purely affective disorders. all of the compared systems to be more sig­
The same applies, although to a lower de­ nificant for attribution to schizophrenia
gree, to the occurrence of basic symptoms than FRS.
(table VIII). The fact that the percentage of
patients exhibiting at least one basic symp­
tom is lower than the percentage of patients References
with at least one FRS in each category of 1 Andreasen, N.C.: Negative symptoms in schizo­
affective disorders may indicate that the phrenia. Archs gen. Psychiat. 39: 784-788
compared algorithms consider basic symp­ (1982).
toms to be superior to FRS as indicators for 2 Berner, P.: Der Lebensabend des Paranoikers
Wien. Z. NervHeilk. 27: 115-161 (1969).
a ‘real’ schizophrenia. Which FRS or basic
3 Berner, P.: Unter welchen Bedingungen lassen
symptoms were actually present in the pa­ weitere Verlaufsforschungen noch neue Erkennt­
tients assigned to affective disorders could nisse über die endogenen Psychosen erwarten?
not be investigated for this paper. The dif­ Psychiatria clin. 15: 97-123 (1982).
ferences in frequency of FRS and basic 4 Berner. P.; Gabriel, E.; Katschnig, H.; Kieffcr, W.;
symptoms between the compared assign­ Koehler, K.; Lenz, G.; Simhandl, C.: Diagnostic
criteria for schizophrenic and affective psychoses
ments to affective disorders can be ex­ (American Psychiatric Press, Washington 1983).
plained by the particularities of each algo­ 5 Bland, R.C.; Orn, H.: Schizophrenia: Schneider’s
rithm. Thus, for instance, the St. Louis cri­ first-rank symptoms and outcome. Br. J. Psychiat.
teria and the RDC show lower percentages /J7. 63-68 (1980).
6 Bleuler, E.: Die Prognose der Dementia praecox
of FRS and basic symptoms than Taylor’s
(Schizophreniegruppe). Allg. Z. Psychiat. 65:436-
system because both contain certain schizo­ 464 (1908).
phrenic symptoms as criteria for exclusion, 7 Bleuler, M.: Eugen Bleuler and schizophrenia. Br.
whilst Taylor’s ‘broad affect’ is the only ele­ J. Psychiat. 144: 326-333 (1984).
ment leading to the exclusion of schizo­ 8 Bürger-Prinz, H.: Probleme der phasischen Psy­
chosen (Enke, Stuttgart 1961).
phrenic patients.
9 Carlson, G.A.; Goodwin, F.K.: The stages of ma­
As is shown in tables VII, VIII, the nia. A longitudinal analysis of the manic episode.
percentage of FRS and basic symptoms is Archs gen. Psychiat. 28: 221-228 (1973).
generally much lower in patients assigned to 10 Carpenter, W.T., Jr.; Strauss, J.S.; Muleh, S.: Arc
depression than in those attributed to ma­ there pathognomonic symptoms in schizophre­
nia? An empiric investigation of Kurt Schneider’s
nia. This may be explained by the assump­
first-rank symptoms. Archs gen. Psychiat. 28:
tion that the diagnosis of mania includes 847-852 (1973).
128.111.121.42 - 3/3/2018 7:41:16 PM

more patients presenting ‘mixed states’ than 11 Carpenter, W.T., Jr.; Strauss, J.S.: Cross-cultural
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the depressives, the latter suffering, accord­ evaluation of Schneider’s first-rank symptoms of
Downloaded by:
252 Berncr/Katschnig/Lcnz

schizophrenia: a report from the International Pi­ 22 Nunn, C.M.H.: Mixed affective states and natural
lot Study of Schizophrenia. Am. J. Psychiat. 131: history of manic-depressive psychosis. Br. J. Psy­
682-687 (1974). chiat 134: 153-160 (1979).
12 Hoenig, J.: Kurt Schneider and anglophone psy­ 23 Pope, H.G.; Lipinski. J.F.: Diagnosis in schizo­
chiatry. Compreh. Psychiat. 23: 391-344 (1982). phrenia and manic-depressive illness. A reassess­
13 Hoenig, J.: The concept of schizophrenia. Kraepe- ment of the specificity of ‘schizophrenic’ symp­
lin - Bleuler - Schneider. Br. J. Psychiat. 142: toms in the light of current research. Archs gen.
547-556 (1983). Psychiat. 35: 811-828 (1978).
14 Huber, G.; Gross, G.; Schüttler, R.: Schizophrenic 24 Pope, H.G.; Lipinski, J.F.; Cohen, B.M.; Axelrod,
(Springer, Berlin 1979). D.T.: Schizoaffective disorder: an invalid diagno­
15 Janzarik, W.: Dynamische Grundkonstellation in sis? A comparison of schizoaffective disorder,
endogenen Psychosen (Springer, Berlin 1979). schizophrenia and affective disorder. Am. J. Psy­
16 Katschnig, H.; Berner, P.: The poly-diagnostic ap­ chiat 137: 921-927 (1980).
proach in psychiatric research. Proc. Int. Conf. 25 Schneider, C.: Die schizophrenen Symptomvcr-
Diagnosis and Classification of Mental Disorders bande (Berlin 1942).
and Alcohol and Drug Related Problems, Copen­ 26 Schneider, K.: Clinical psychopathology (Grune &
hagen 1982 (World Health Organization, Geneva Stratton, New York 1959).
1983). 27 Wing, J.K.; Cooper, J.E.; Sartorius, N.: Measure­
17 Koehler, K.; Guth, W.; Grimm, G.: First-rank ment and classification of psychiatric symptoms
symptoms of schizophrenia in Schneider-oriented (Cambridge University Press, Cambridge 1974).
German centers. Archsgcn. Psychiat. 34: 810-813 28 World Health Organization: The International Pi­
(1977). lot Study of Schizophrenia, vol. 1 (World Health
18 Koehler, K.: First-rank symptoms of schizophre­ Organization, Geneva 1973).
nia: questions concerning clinical boundaries. J.
Psychiat. 134: 235-248 (1979).
19 Mayer, W.: Über paraphrene Psychosen Z. ges.
Neurol. Psychiat. 26: 78-80 (1921). P. Berner, MD,
20 Mellor, C.S.: First-rank symptoms of schizophre­ Psychiatric Clinic,
nia. Br. J. Psychiat. 117: 15-23 (1970). University of Vienna,
21 Mentzos, S.: Mischzustände und mischbildhafte Währinger Gürtel 74-76,
phasische Psychosen (Enke, Stuttgart 1967). A -1097 Vienna (Austria)

128.111.121.42 - 3/3/2018 7:41:16 PM


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