MIC charts: Sentinel M

Organism: Staphylococcus aureus

Collection Program: CDC Sentinel AST Surveillance

Dates of specimen collection: Clinical isolates collected during 2013-2017
Collection Protocol: Convenience sample of clinical isolates from participating US h
Standard reference AST method used: Determination of MIC by reference broth m
 MIC charts: Sentinel MIC data (CDC)

ates collected during 2013-2017

of clinical isolates from participating US hospital laboratories
ermination of MIC by reference broth microdilution performed at CDC using in-house prepared drug panels

Organism: Staphylococcus aureus

Select/Search Drug
Oxacillin
Penicillin
Cefoxitin
Ceftaroline
Clindamycin
Erythromycin
Daptomycin
Gentamycin
Doxycycline+
Tetracycline
Levofloxacin
Linezolid
Mupirocin
Sulfamethoxazole-Trimethoprim
Vancomycin
Rifampin
Organism Staphylococcus aureus 1200
1079
Oxacillin MIC (mcg/Count of Oxacillin MIC (mcg/ml)
0.249 439 1000
0.5 105
1 19
2 12 800
4 33
8 76
600
16 164
17 231
439
Total Result 1079
400

231
200 164
105
76
19 12 33
0

17
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76
16

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Organism - all - 1200

1079
Penicillin MIC (mcg Count of Penicillin MIC (mcg/ml)
0.059 136
1000
0.12 14
0.25 22
0.5 37
800 764
1 46
2 60
2.1 764
Total Result 1079 600

400

200
136

46 60
22 37
14
0

1
12

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1079
Organism Staphylococcus aureus
1200

Ceftaroline MIC (m Count of Ceftaroline MIC (mcg/ml)

0.249 581 1079
0.5 406
1 90 1000
2 2
Total Result 1079

800

600 581

406
400

200

90

2
0
0.249 0.5 1 2 Total
Result

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Organism Staphylococcus aureus
1200

Clindamycin MIC (mCount of Clindamycin MIC (mcg/ml)

1079
0.249 847
0.5 15
1 4 1000

2 1
4 1
847
8 1
16 2 800
17 208
Total Result 1079

600

400

208
200

15 4 1 1 1 2
0
9

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2
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1079
Organism Staphylococcus aureus 1200

Erythromycin MIC ( Count of Erythromycin MIC (mcg/ml) 1079

0.249 35
1000
0.5 261
1 94
2 4
4 11 800
8 19
8.1 655 655
Total Result 1079 600

400

261

200

94
35 19
4 11
0

1
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Organism Staphylococcus aureus 1200

Daptomycin MIC (mCount of Daptomycin MIC (mcg/ml) 1078

0.49 957
1 112 1000
957
2 5
4 4
Total Result 1078
800

600

400

200

112

5 4
0
0.49 1 2 4 Total
Result

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Organism Staphylococcus aureus

Gentamycin MIC (mCount of Gentamycin MIC (mcgml) 1200

1.9 990
4 12
8 2
16 3 1030
32 5 1000 990
33 18
Total Result 1030

800

600

400

200

12 5 18
2 3
0
4

8
9

16

32

33

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1030
Organism Staphylococcus aureus
1200

Doxycycline MIC (mCount of Doxycycline MIC (mcg/ml)

0.9 1007 1079
2 32
4 18 1007
1000
8 19
16 3
Total Result 1079

800

600

400

200

32
18 19
3
0
0.9 2 4 8 16 Total
Result

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Organism - all -
1200

Tetracycline MIC ( Count of Tetracycline MIC (mcg/ml) 1079

0.9 973
2 21 1000 973
4 15
8 10
16 6
17 54 800
Total Result 1079

600

400

200

54
21 15 10 6
0
0.9 2 4 8 16 17 Total
Result

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 1079

54
6
16 17 Total
Result
Organism Staphylococcus aureus
1200

Levofloxacin MIC ( Count of Levofloxacin MIC (mcg/ml) 1079

0.49 567
1 6 1000
2 7
4 195
8 81
800
16 57
17 166
Total Result 1079
600 567

400

195
200 166

81
57
6 7
0

49

16

17

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8

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16

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1079
Organism Staphylococcus aureus
1200

Linezolid MIC (mcg Count of Linezolid MIC (mcg/ml) 1079

<= 1 88
1000
2 718
4 273
Total Result 1079
800
718

600

400

273

200

88

0
<= 1 2 4 Total
Result

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Organism Staphylococcus aureus
1200

Mupirocin MIC (mcCount of Mupirocin MIC (mcg/ml) 1079

3.9 1012
1012
8 7 1000
16 11
32 9
257 40
Total Result 1079 800

600

400

200

40
7 11 9
0
9

16

32

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Organism - all - 1200

Rifampin MIC (mcg/Count of Rifampin MIC (mcg/ml)

0.49 1060 1079
1060
1 3
2 3 1000
8 3
8.1 10
Total Result 1079

800

600

400

200

3 3 3 10
0
0.49 1 2 8 8.1 Total
Result

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Organism Staphylococcus aureus
1200

Sulfamethoxazole-TCount of Sulfamethoxazole-Trimethoprim MIC (mcg/ml)

0.49 1037
1 12 1037
2 4 1000
4 3
8.1 23
Total Result 1079

800

600

400

200

12 23
4 3
0

1
49

8.
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1200

1079
1037

1000

800

600

400

200

12 23
4 3
0
1

1
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Organism - all -
1200
Vancomycin MIC (mCount of Vancomycin MIC (mcg/ml)
1079
0.49 511
1 559
1000
2 9
Total Result 1079

800

600
559
511

400

200

9
0
0.49 1 2 Total
Result

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 1200

Cefoxitin MIC (mcg Count of Cefoxitin MIC (mcg/ml)

1079
1.9 96
4 447 1000
8 20
16 210
17 306
Total Result 1079 800

600

447

400
306

210
200

96

20
0
1.9 4 8 16 17 Total
Result

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 1079

306

17 Total
Result