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VOLUME I – Diagnosis

∠ From the editors: Introducing the digital edition of The PCR-EAPCI Percutaneous Interventional
Cardiovascular Medicine Textbook (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=168)
Christoph K. Naber, Andreas Baumbach, Alec Vahanian

∠ Foreword: A European touch (/eurointervention/textbook/pcr-textbook/chapter/?chap-

ter_id=164)
Valentin Fuster

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 ∠ Foreword: Why a textbook? Why this textbook? (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=165)
Spencer B. King, III

∠ Preface: PCR-EAPCI Percutaneous Interventional Cardiovascular Medicine Textbook: a step and

benchmark for a future model in education (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=163)
Jean Marco, chairman of PCR and Jean Fajadet, president of EAPCI

∠ Introduction: Bringing it all together, the Genesis of the PCR EAPCI textbook (/eurointerven-
tion/textbook/pcr-textbook/chapter/?chapter_id=167)
Eric Eeckhout, Patrick W. Serruys, William Wijns, Alec Vahanian, Marc van Sambeek, Rodney de Palma

Part I – Foundations of interventional cardiovascular medicine

∠ A history of cardiac catheterisation (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=64)
Michel E. Bertrand, Bernhard Meier
∠ A history of percutaneous coronary intervention (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=65)
Michel E. Bertrand, Bernhard Meier
∠ Right and left heart catheterisation (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=66)
Morton J. Kern
∠ Vascular access (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=67)
! 2014 !2
Olivier Bertrand, Rodney de Palma, David Meerkin
∠ Vascular closure (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=68)
Anouska M. Moynagh, Marie-Claude Morice ! 2016
∠ Cardiac transseptal catheterisation (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=69)
Gregory Ducrocq, Thomas R.D. Shaw, Habib Gamra, Peter C. Block, Neil R. Grubb, Carlos E. Ruiz, Alec Vahanian ! 2015
∠ Catheterisation for peripheral diagnostic and interventional procedures (/eurointerven-
tion/textbook/pcr-textbook/chapter/?chapter_id=70)
Marco Roffi, Robert F. Bonvini
∠ Cardiac catheterisation in children and adults with grown-up congenital heart disease (/euroin-
tervention/textbook/pcr-textbook/chapter/?chapter_id=71)
Ingo Daehnert, Philipp Lurz, Philipp Bonhoeffer
∠ Endomyocardial biopsy (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=72)
Ali Yilmaz, Karin Klingel, Reinhard Kandolf, Udo Sechtem
∠ Pericardiocentesis (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=73)
John D. Groarke, Andrew O. Maree, Igor F. Palacios " ! 2016
∠ Percutaneous ventricular assistance (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=74)
Juan N. Pulido, Charanjit S. Rihal ! 2016
∠ Radiation protection (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=75)

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 Eugenio Picano, Maria Grazia Andreassi, Madan M. Rehani, Leonardo Bolognese, Eliseo Vano
∠ Contrast agents and renal protection (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=76)
Antonio L. Bartorelli, Giancarlo Marenzi ! 2014
∠ Sedation, pain management and resuscitation (/eurointervention/textbook/pcr-textbook/chap-
ter/?chapter_id=77)
Linda Veldmeijer, Ingeborg HF. Herold, Erik Korsten
∠ Biostatistics for the interventionist (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=78)
Tim Collier, Stuart Pocock

Part II – Diagnostic cardiovascular modalities and their application

∠ Cardiac biomarkers (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=79)
Evangelos Giannitsis, Christian Hamm, Holger Nef, Hugo A. Katus ! 2013
∠ Fundamentals of coronary biomechanics (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=80)
Frank Gijsen, Peter Mortier, Matthieu De Beule, Jolanda Wentzel, Patrick Segers
∠ Non-invasive imaging for coronary disease (/eurointervention/textbook/pcr-textbook/chap-
ter/?chapter_id=81)
Juhani Knuuti, Antti Saraste, Sami Kajander, Heikki Ukkonen, Juha Koskenvuo " ! 2014
∠ Non-invasive imaging for structural heart disease (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=82)
Victoria Delgado, Nina Ajmone Marsan, Maarten Witsenburg, Carl Schultz, Martin J. Schalij, Jeroen J. Bax ! 2014
∠ Imaging for peripheral artery disease (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=83)
Peter M. Pattynama ! 2016
∠ Invasive diagnostic coronary angiography (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=84)
Guy R. Heyndrickx, Aaron J. Peace, Chrysafios Girasis, Christoph K. Naber, Christos V. Bourantas, Patrick W. Serruys " !
2015
∠ Invasive haemodynamic assessment (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=85)
Paul Sorajja, Rick A. Nishimura
∠ Invasive physiological assessment of coronary disease (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=86)
! 2014 !2
Pim A.L. Tonino, Jan-Willem E.M. Sels, Nico H.J. Pijls
∠ Assessment of coronary vasoreactivity and the microcirculation (/eurointervention/text-
book/pcr-textbook/chapter/?chapter_id=87)
Thomas F Lüscher, Andreas F. Flammer, Amir Lerman
∠ Intracardiac echocardiography (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=88)
Anna E. Bortnick, Frank E. Silvestry, Howard C. Herrmann "
∠ Intravascular ultrasound (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=89)
Hector M. García-García, Fernando Alfonso ! 2015

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 ∠ Optical coherence tomography (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=90)
Evelyn Regar, Francesco Prati " ! 2016
∠ Near-infrared spectroscopy (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=91)
James A. Goldstein, Salvatore Brugaletta, Sean P. Madden, Stephen T. Sum, Simon R. Dixon, Ryan D. Madder, Patrick W.
Serruys, James E. Muller ! 2015

VOLUME II – Intervention I

Part III – Percutaneous interventions for cardiovascular disease

∠ Guide catheters and wires (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=92)
Soo Teik Lim, Tian Hai Koh " ! 2016 !2
∠ Balloon angioplasty technology (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=93)
Tassilo Bonzel, Christian Hamm, Volker Schächinger, Gerhard Strupp, Didier Tchetche ! 2014
∠ Coronary artery stents (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=94)
Scot Garg, Anna Franzone, Patrick W Serruys, Stephan Windecker ! 2015
∠ Bioresorbable scaffolds (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=95)
Yoshinobu Onuma, Antoine Lafont, Alexandre Abizaid, Ron Waksman, John Ormiston, Patrick W. Serruys ! 2015
∠ Drug-coated balloons (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=96)
Bruno Scheller ! 2016
∠ Rotational atherectomy (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=97)
Farrel Hellig, Shaheen Pandie, Emanuele Barbato, Antonio Colombo, Guy R. Heyndrickx " ! 2015
∠ Directional atherectomy (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=98)
Antonio Colombo, Azeem Latib
∠ Laser therapy (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=99)
Michael Haude, Miltos Papalexandris, Hubertus Degen
∠ Distal protection and thrombectomy (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=100)
Marco Valgimigli, Simone Biscaglia
∠ Bifurcation lesions (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=101)
! 2016 !2
Thierry Lefèvre, Yves Louvard, Marie-Claude Morice
∠ Ostial lesions (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=102)
Christoph K. Naber, Thomas Schmitz, Eberhard Grube, Georg V. Sabin
∠ Left main coronary artery disease (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=103)
Vasim Farooq, Patrick W. Serruys, Greg W. Stone, Renu Virmani, Alaide Chieffo, Jean Fajadet ! 2015

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 ∠ Chronic total occlusions (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=104)
Gerald S. Werner ! 2015
∠ Saphenous vein graft disease (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=105)
Gabriel Maluenda, Pierfrancesco Agostoni, Pieter R. Stella, Paul Vermeersch, Itsik Ben-Dor, Lowell F. Satler, Ron Waksman,
Augusto D. Pichard ! 2015
∠ Risk stratification and risk models in revascularisation (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=106)
Scot Garg, David R. Holmes ! 2015
∠ Interventions for stable coronary disease (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=107)
Pradyumna E. Tummala, Bill D. Gogas, Robert Guyton, David O. Williams, Spencer B. King III ! 2015
∠ Interventions for ST-segment elevation acute myocardial infarction (/eurointervention/text-
book/pcr-textbook/chapter/?chapter_id=108)
Dariusz Dudek, Carlo Di Mario, Giuseppe De Luca, Artur Dziewierz, Tomasz Rakowski ! 2016
∠ Interventions for non-ST-segment elevation acute coronary syndromes (/eurointerven-
tion/textbook/pcr-textbook/chapter/?chapter_id=109)
Helge Möllmann, Holger M. Nef, Sebastian Szardien, Jean-Pierre Bassand, Christian W. Hamm
∠ Interventions for patients with diabetes mellitus (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=110)
Manel Sabaté ! 2016
∠ Lesion and patient subsets: chronic kidney disease (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=111)
Flavio Ribichini, Roberto Scarsini, Gabriele Pesarini, Valeria Ferrero, Corrado Vassanelli ! 2016
∠ Secondary revascularisation (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=112)
Hernán David Mejía-Rentería, Nieves Gonzalo, Javier Escaned ! 2016
∠ Hybrid interventions (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=113)
Oana Bodea, Frank Van Praet, Hugo Vanermen, Philippe Kolh, Bernard De Bruyne
∠ Cardiogenic shock (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=114)
Holger Thiele, Pascal Vranckx, Gerhard Schuler ! 2014 !2
∠ The prevention and management of complications during percutaneous coronary intervention
(/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=115)
Rodney De Palma, Christian Roguelov, Adel Aminian, Olivier Muller, Tito Kabir, Eric Eeckhout
∠ Stent thrombosis (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=116)
Dean J. Kereiakes, Ian J. Sarembock ! 2015
∠ In-stent restenosis (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=117)
Vasim Farooq, Lorenz Räber, Bill D. Gogas, Patrick W. Serruys ! 2015
∠ Peri-procedural and post-procedural antithrombotic pharmacotherapy (/eurointerven-
tion/textbook/pcr-textbook/chapter/?chapter_id=118)
Kurt Huber ! 2016 !2
∠ Secondary prevention and follow-up (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=119)
Francois Schiele ! 2015

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 VOLUME III – Intervention II

Part III – Percutaneous interventions for cardiovascular disease

∠ Percutaneous balloon mitral commissurotomy (/eurointervention/textbook/pcr-text-
book/chapter/current/120.html) ! Chapter under update
Alec Vahanian, Dominique Himbert, Eric Brochet, Gregori Ducrocq, Marina Urena, Bernard Iung
∠ Percutaneous mitral valve repair (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=121)
Ted Feldman, Olaf Franzen ! 2015
∠ Balloon aortic valvuloplasty (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=122)
Hélène Eltchaninoff, John G. Webb "
∠ Transcatheter aortic valve implantation (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=123)
Nicolo Piazza, Alain Cribier " !3
∠ Percutaneous pulmonary valvuloplasty (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=124)
Louise Coats, Philipp Lurz, Ingo Daehnert, Philipp Bonhoeffer "
∠ Percutaneous pulmonary valve implantation (/eurointervention/textbook/pcr-textbook/chap-
ter/?chapter_id=125)
Robert Wagner, Ingo Daehnert, Philipp Bonhoeffer, Philipp C. Lurz ! 2016
∠ Atrial septal defect and patent foramen ovale closure (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=126)
Jochen Wöhrle " ! 2016
∠ Ventricular septal defect closure (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=127)
Gianfranco Butera, Quang N. Nguyen, Biagio Castaldi, Luciane Piazza, Massimo Chessa, Mario Carminati " ! 2016
∠ Patent ductus arteriosus closure (/eurointervention/textbook/pcr-textbook/chapter/cur-
rent/128.html) ! Chapter under update
Massimo Chessa, Biagio Castaldi, Gianfranco Butera, Diana Gabriela Negura, Mario Carminati
∠ Left atrial appendage occlusion (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=129)
Daniel H. Steinberg, Stefan Bertog, Jennifer Franke, Jens Wiebe, Nina Wunderlich, Horst Sievert ! 2014
∠ Coarctation of the aorta (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=130)
Benjamin G. Smith, Shakeel A. Qureshi ! 2016
∠ Interventions for congenital and acquired pulmonary vein stenosis (/eurointervention/text-
book/pcr-textbook/chapter/?chapter_id=131)

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 James .R. Bentham, Neil. Wilson
∠ Percutaneous closure of paravalvular leaks (/eurointervention/textbook/pcr-textbook/chap-
ter/?chapter_id=166)
Carlos E. Ruiz, Yuriy Dudiy, Vladimir Jelnin, Itzhak Kronzon, Bryce N. Einhorn, Howard A. Cohen " ! 2015
∠ Carotid artery stenting (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=132)
Alberto Cremonesi, Marco Roffi, Estevao Carvalho De Campos Martins, Fausto Castriota ! 2016
∠ Subclavian, brachiocephalic and vertebral interventions (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=133)
Alberto Cremonesi, Marco Roffi, Estevao Carvalho De Campos Martins, Fausto Castriota ! 2016
∠ Thoracic and abdominal aortic disease (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=134)
Christoph A. Nienaber, Edith M. Willigendael, Ibrahim Akin, Stephan Kische, Marc R.H.M. Van Sambeek
∠ Interventions in the reno-visceral circulation (/eurointervention/textbook/pcr-textbook/chap-
ter/?chapter_id=135)
Thomas Zeller ! 2014
∠ Peripheral arterial occlusive disease (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=136)
Nicolas Diehm, Alberto Cremonesi, Andrej Schmidt, Dierk Scheinert, Iris Baumgartner !2
∠ Interventions for varicose veins (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=137)
Renate R. Van Den Bos, Mickael A. Kockaert, Martino H.A. Neumann ! 2016
∠ Closure of arteriovenous fistulae and malformations (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=138)
Stefan C. Bertog, Daniel H. Steinberg, Jennifer Franke, Nina Wunderlich, Horst Sievert, Peter N. Ruygrok ! 2015
∠ Alcohol septal ablation for hypertrophic obstructive cardiomyopathy (/eurointervention/text-
book/pcr-textbook/chapter/?chapter_id=139)
Hubert Seggewiss, Angelos G. Rigopoulos ! 2015
∠ Alternative techniques to alcohol septal ablation for hypertrophic obstructive cardiomyopathy
(/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=140)
Bachir Allam, Eric Durand, Antoine Lafont ! 2015
∠ Concept, Techniques and Clinical Effectiveness of Renal Nerve Ablation in Hypertension (/eu-
rointervention/textbook/pcr-textbook/chapter/?chapter_id=141)
Isabella Sudano, Christian Templin, Milosz Jaguszeweski, Ulf Landmesser, Felix Mahfoud and Thomas F. Lüscher
∠ Techniques of myocardial stem cell delivery (/eurointervention/textbook/pcr-textbook/chap-
ter/?chapter_id=142)
Jozef Bartunek, Anthony Mathur, Marc Vanderheyden "
∠ Cell-based regenerative therapy (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=143)
Abdul M. Mozid, Samer Arnous, Matthew Lovell, Anthony Mathur
∠ Pulmonary embolism and pulmonary hypertension (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=144)
Klaus Distelmaier, Irene M. Lang ! 2015
∠ Endovascular treatment of acute ischemic stroke (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=171)

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 Maxim Mokin, Adnan H. Siddiqui, Elad I. Levy, L. Nelson Hopkins ! 2016

VOLUME IV – Perspectives

Part IV – Interventional cardiovascular medicine into context

∠ The Heart team (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=145)
! 2014 !1
Stuart J. Head, Nicolas M. Van Mieghem, Patrick W. Serruys, Arie Pieter Kappetein
∠ Patient information, ethics, and informed consent (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=146)
Daniel Bromage, Marko Noc, Jean Marco
∠ The cardiac catheterisation laboratory environment (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=147)
Jacques J. Koolen, Rodney De Palma, Lukas Dekker
∠ Administration and data collection (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=148)
Andreas Baumbach, Peter F Ludman
∠ Registry studies and post-marketing surveillance (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=149)
Stefan James, Ole Fröbert ! 2015
∠ Clinical trial design (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=150)
Pallav Garg, Adnan Kastrati, Laura Mauri
∠ Quality of life assessment (/eurointervention/textbook/pcr-textbook/chapter/?
chapter_id=151)
Mattie Lenzen, Ron Van Domburg, Susanne S. Pedersen ! 2016
∠ Risk-benefit analysis (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=152)
Salvatore Brugaletta, Patrick W. Serruys, Vasim Farooq, Arie Pieter Kappetein, Sally C. Stearns ! 2015
∠ Cost and cost-effectiveness (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=153)
Isabelle Durand-Zaleski ! 2013
∠ Interventional cardiology training (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=154)
Carlo Di Mario, Martine Gilard, Lino Goncalves, Ulf Jensen
∠ Consensus on definitions of clinical endpoints: percutaneous coronary and valvular interven-
tion trials (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=155)
Pascal Vranckx, Donald E. Cutlip, Roxana Mehran, Martin B. Leon, Patrick W. Serruys ! 2014 !2
∠ Consensus on definitions of clinical endpoints : carotid artery and supra-aortic trunk revascu-
larisation trials (/eurointervention/textbook/pcr-textbook/chapter/?chapter_id=156)
Alberto Cremonesi, Marco Roffi, Carlo Setacci

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 Part V – Annexes
∠ Interventional pharmacology (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=157)
Sotiris Antoniou, Paul Wright, Rodney de Palma
∠ Interventional innovation landscape (/eurointervention/textbook/pcr-textbook/chapter/?chap-
ter_id=158)
Hollis Call, Eric Lehto, Paul Cummins, Patrick W. Serruys ! 2014
∠ ARC definitions of clinical endpoints for interventional trials (/eurointervention/textbook/pcr-
textbook/chapter/?chapter_id=159)
Pascal Vranckx, William Wijns
∠ Cardiology audit and registration data standards (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=160)
∠ Abridged ESC guidelines for interventional practice (/eurointervention/textbook/pcr-text-
book/chapter/?chapter_id=161)
! 2015
∠ The global burden of cardiovascular disease (/eurointervention/textbook/pcr-textbook/chap-
ter/?chapter_id=162)
! 2015

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