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Hypothyroidism Diagnosis Flowchart

Signs or symptoms
of hypothyroidism

Measure serum TSH

TSH > 5.5 mlU per L TSH in normal range TSH < 0.35 mIU per L*

Measure serum free T₄ Patient is euthyroid Consider


hyper-thyroid state

Free T₄ is below Free T₄ is within Free T₄ is above


normal range normal range normal range

Primary Subclinical Not primary


hypothyroidism hypothyroidism hypothyroidism

*—TSH reference ranges may vary depending on the laboratory.

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