Shree.

Rishikesh Shikshan Prasarak Mandal, Navi Mumbai’s

Shri. D. D. Vispute College of Pharmacy & Research Center, New
Panvel

MOCK TEST MCQ

SUB: PHARMACOLOGY – II CLASS: THIRD YEAR B. PHARMACY

PATTERN: CBCS SEM – V

1) Actions of thyroxin do not include

(a) Acceleration of cardiac rate
(b) Decreased glomerular filtration rate
(c) Fine tremor of skeletal muscles
(d) Increased appetite

2) Effects of iodide salts given in large doses do not include

(a) Decreased size of the thyroid gland
(b) Decreased vascularity of the thyroid gland
(c) Decreased hormone release
(d) Increased 131I uptake
3) Insulin preparations that contain a modifying protein include
(a) Lente insulin
(b) Regular insulin
(c) Isophane insulin (NPH)
(d)Ultralinete insulin

4) Which of the following insulins can be administered intravenously?

(a) Regular insulin
(b) Isophane insulin (NPH)
(c) Protamine zinc insulin (PZi)
(d) Semilente insulin

5) Severe cases of bleeding due to fibrinolytic agents are treated with

(a) Aspirin
(b) Heparin
(c) EACA (Epsilon Amino Caproic Acid)
 (d) Vitamin K

6) The preferred route of administration of streptokinase in acute myocardial

infarction is
(a) Intravenous
(b) Subcutaneous
(c) Intracoronary
(d) Intracardiac

7) Which one of the following agents is not used in oral or implantable contraceptives?
(a) Clomiphene
(b) Ethinyl estradiol
(c) Mestranol
(d) Norethindrone

8) Drug of choice in treating autoimmune hemolytic anemia:

(a) cyclophosphamide plus factor XIII
(b) Rho (D) immune globulin
(c) Prednisone
(d) OKT3 monoclonal antibody

9) HIV is a retrovirus that infects and colonizes cells in the ______.

(a) immune system
(b) immune system and the central nervous system
(c) endocrine system
(d) immune system and endocrine system

10) Which of the following immunosuppressant drugs is nephrotoxic?

(a) Azathioprine
(b) Cyclophosphamide
(c) Mycophenolate mofetil
(d) Tacrolimus
11) Monocytes move from the systemic circulatory system into general connective
tissues, where they differentiate into what phagocytic cell type?
(a) Macrophage
(b) T- Cell
(c) B- Cell
(d) Neutrophil

12) Which of the following cell types of the innate immune system does not perform
phagocytosis?
(a) Neutrophils
(b) Basophils
(c) Macrophages
(d) Eosinophils

13) Which of the following chemotherapy agents has demonstrated the ability to cause
accelerated rheumatoid nodule formation?
(a) Cisplatin
(b) Methotrexate
(c) Paclitaxel
(d) rituximab

14) Major toxicity of alkylating drugs:

(a) Alopecia
(b) Myelosuppression
(c) renal damage
(d) hepatic failure

15) Most useful alkylating drug currently available:

(a) melphalan (Alkeran)
(b) cyclophosphamide (Cytoxan)
(c) lomustine (CCNU,CeeNU)
(d) thiopeta (Thioplex)
16) Nitrosourea with minimal bone-marrow suppression and effective in treating
pancreatic, islet cell carcinoma.
 (a) Lomustine
(b) Carmustine
(c) Streptozocin
(d) procarbazine
17) Anticancer drug that is also used to treat psoriasis and rheumatoid arthritis:
(a) mercaptomurine (6-MP)
(b) methotrexate
(c) procarbazine (Matulane)
(d) allopurinol (Zyloprim, Purinol)
18) Anticancer agent that works by depolymerization of microtubules:
(a) azatadine (Optimine)
(b) vinblastine (Velban)
(c) cladribine (Leustatin)
(d) methotrexate
19) Among anticancer antibiotics: most toxic--
(a) Plicamycin (Mithramycin)
(b) Dactinomycin (Cosmegen)
(c) Doxorubicin (Adriamycin)
(d) Bleomycin (Blenoxane)
20) Natural adrenocortical hormones are produced in released by:
(a) Pituitary
(b) Hypothalamus
(c) Adrenal cortex
(d) Liver
21) Adrenocortical steroid secretion is mainly controlled by:
(a) angiotensin release
(b) renin
(c) calcitonin
(d) corticotrophin

22) Choose the antimicrobial which acts by interfering with DNA function in the
bacteria:
A. Chloramphenicol
B. Ciprofloxacin
C. Streptomycin
 D. Vancomycin

23) Indicate the sulfonamide whose sodium salt yields a nearly neutral solution which
is suitable for topical use in the eye:
A. Sulfadiazine
B. Sulfacetamide
C. Sulfadoxine
D. Sulfamoxole

24) The following quinolone antimicrobial agent is not useful in systemic infections:
A. Lomefloxacin
B. Ofloxacin
C. Nalidixic acid
D. Pefloxacin

25) The following antibiotic is a first line drug for treatment of Mycobacterium avium
complex infection in AIDS patients:
A. Clindamycin
B. Clarithromycin
C. Roxithromycin
D. Erythromycin