STEP 1 REVIEW COURSE - PART 1

SET 30

SET 30

1. What landmarks are used when placing an internal jugular central venous catheter?
(COA p1011)

2. A patient presents with a 1 cm, painless, mobile mass in her right parotid gland. You inform
the patient that most tumors in the parotid gland are benign. What is the most common
benign tumor of the salivary gland? What is a Warthin’s tumor? Which cranial nerve goes
through the parotid gland?
(FA18 p370, 490) (FA19 p370, 494) (SU p41, 119)

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STEP 1 REVIEW COURSE - PART 1

SET 30
3. What is the characteristic fetal complication associated with lithium use in pregnancy?
What other agents used to treat bipolar disorder can be teratogenic, and what are their
corresponding fetal effects?
(FA18 p294, 296, 545) (FA19 p296, 298, 549) (SU p16)

4. What is the mechanism of organophosphate poisoning? What are the symptoms of

cholinergic excess?
(FA18 p236) (FA19 p240) (SU p402)

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 STEP 1 REVIEW COURSE - PART 1
SET 30
5. The parents of a 5-year-old girl are concerned because their daughter has night terrors,
sleepwalking, and enuresis (bedwetting). In which stage of sleep do these occur? What
medications shorten this stage of sleep and thus are useful in treating night terrors,
sleepwalking, and enuresis?
(FA18 p481) (FA19 p485) (SU p42-43)

6. A 22-year-old man suffers a stabbing injury to the chest. He has lost a lot of blood, and
you are concerned that his cardiac output is low. What are the two equations for cardiac
output?
(FA18 p278) (FA19 p283) (SU p68)

7. A 5-year-old boy is treated with mebendazole for a pinworm infection. Mebendazole acts
on microtubules to inhibit the pinworms. What other medications act on microtubules?
What syndrome demonstrates a defect in microtubule polymerization?
(FA18 p48) (FA19 p48)

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 STEP 1 REVIEW COURSE - PART 1
SET 30
8. What is the mechanism of action of local anesthetics? Which nerve fibers are blocked first
with local anesthesia?
(FA18 p533) (FA19 p537)

9. What are the three different eukaryotic RNA polymerases? What type of RNA does each
make?
(FA18 p41) (FA19 p42) (SU p284)

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STEP 1 REVIEW COURSE - PART 1

SET 30
10. What is the rule of 2s associated with a Meckel diverticulum?
(FA18 p378) (FA19 p378) (SU p118)

*Page references are as follows:

FA18: First Aid for the USMLE Step 1 2018

FA19: First Aid for the USMLE Step 1 2019
SU: Step-Up to USMLE Step 1 2015
R: Robbins and Cotran Pathologic Basis of Disease, 9th ed. (2015)
Phys: Guyton and Hall Textbook of Medical Physiology, 13th ed. (2016)
H: Harrison’s Principles of Internal Medicine, 19th ed. (2015)
COA: Clinically Oriented Anatomy, 7th ed. (2014)
GG: Goodman and Gilman’s Pharmacological Basis of Therapeutics, 12th ed. (2011)

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