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  • Pedigree Analysis Problem

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    Rejean Padre
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    This document contains two family case studies with genetic questions. For the first case of a rare skin disease: the inheritance is likely autosomal recessive; the first generation would be carriers (heterozygous); generations III individuals 9 and 10 could be homozygous affected, carriers, or normal; and there is a 50% chance the offspring would have the disease. For the second case of hemophilia: the inheritance is likely X-linked recessive; the first generation would be a carrier female and normal male; generation II individuals 5 and 1 could be a carrier female and normal male; and the son of generation III individual 2 has a 50% chance of being affected.

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    pedigree-analysis-problem

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    This document contains two family case studies with genetic questions. For the first case of a rare skin disease: the inheritance is likely autosomal recessive; the first generation would be carriers (heterozygous); generations III individuals 9 and 10 could be homozygous affected, carriers, or normal; and there is a 50% chance the offspring would have the disease. For the second case of hemophilia: the inheritance is likely X-linked recessive; the first generation would be a carrier female and normal male; generation II individuals 5 and 1 could be a carrier female and normal male; and the son of generation III individual 2 has a 50% chance of being affected.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    8 views1 page

    Pedigree Analysis Problem

    Uploaded by

    Rejean Padre
    This document contains two family case studies with genetic questions. For the first case of a rare skin disease: the inheritance is likely autosomal recessive; the first generation would be carriers (heterozygous); generations III individuals 9 and 10 could be homozygous affected, carriers, or normal; and there is a 50% chance the offspring would have the disease. For the second case of hemophilia: the inheritance is likely X-linked recessive; the first generation would be a carrier female and normal male; generation II individuals 5 and 1 could be a carrier female and normal male; and the son of generation III individual 2 has a 50% chance of being affected.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    of 1

    A.

    FAMILY CASE 1 – RARE SKIN DISEASE


    1. Identify the type of inheritance. Explain your answer.
    2. Supposed this is a rare skin disease. What are the genotypes
    of 1 and 2 from the very first generation?
    3. What are the genotypes of 9 and 10 from the IV generation?
    4. What is the possibility that the offspring will have the rare
    disease if number 1 from generation III will marry a man
    with the disease?

    B. FAMILY CASE 2 - HEMOPHILIA

    1. Identify the type of inheritance. Explain your answer.


    2. Supposed this is a pedigree of a hemophiliac family.
    What are the genotypes of 1 and 2 from the very first
    generation?
    3. What are the genotypes of 5 and 1 from the generation
    II?
    4. What are the chances that the son of 2 from generation
    III will be hemophiliac?

    Use the blank space for your answers:

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