PRELIM LAB GEN.

PATHOLOGY LUNG PATHOLOGY

SLIDE SPECIFICATIONS IMAGES

CYTOMEGALOVIRUS  Infection by
PNEUMONIA CMV, a Beta
herps virus

 Haemorrhagic
nodules

 Mono nuclear
infiltrates

 Infected cells
are enlarged
and having
intra nuclear
basophilic
inclusions
surrounded by
clear halo
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
LOBAR PNEUMONIA  Dilation and
congestion of
capillaries in
the A.Walls

 Alveolar
spaces are
filled with
eosinophilic
fluid and RBC
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
LIPID ASPIRATED  Necrotic
PNEUMONIA alveolar tissue
with lipid laden
macrophages

 Vacuoles are
different sized
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
INTERSTITIAL  Widening of
PNEUMONIA interstitium with
clear alveolar
sacs
 Interstitial
edema
congestion and
lymphocyte
infiltrates
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
TUBERCULOSIS  Caseating
granuloma
 Langhan type
giant cell
 Lymphocytes

 Type 4
Hypersensitivity
Delayed
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
ASPERGILOSIS  Dichotomous
branching
aspergillus
hyphae with
septation
 Fungus ball
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
COCCIDIODOMYCOSIS  Spherules with
numerous
endospores

 lymphocyte
infiltrates in
back ground
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
ADULT  Alevolar
RESPIRATORY Hyaline
SYNDROME membranes

 Pink hyaline
materials
deposition in
alveolar wall
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
HYALINE  Also called as
MEMBRANE NRDS
DISEASE
 Deficiency of
pulmonary
surfactant
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
PULMONARY  Deep vein
EMBOLISM thrombosis

 Lines of zahn
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
ACUTE LUNG  Red infarct
INFARCT
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
GOOD PASTURES  Type 2
LUNG hypersensitivity

 Hemosiderin
laden
macrophages
are present
 Intra alveolar
haemorrage
 Fibric alveolar
septa


`
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
CHRONIC PASSIVE  Heart failure
CONGESTION LUNG cells
 Intra alveolar
hemosiderin
laden
macrophages
 Left sided heart
failure
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
ASTHMA  Type 1
Hypersensitivity
 Hypertrophy /
hyperplasia of
branchial wall

 Eosinophills
are present
 Mucus plug is
also present
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY

EMPHYSEMA  Causative
smoking and
alpha 1 anti
trypsin defi.

 Slide shows
Centriacinar
type

 irreversible
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
BRANCHIACTASIS  irreversible
 abnormal
dilatation of
bronchi and
bronchioles
 Acute and
chronic
inflammatory
cells
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
SARCOIDOSIS  Noncaseating
granuloma
 Langhen type
gaint cell
 Type 4
hypersensitivity
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
ANTHRACOSIS  Extensive
fibrosis with
numeorus
black carbon
pigment
 Marked
collagen
deposition
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
ASBESTOSIS  Asbestos body
(Golden brown
Fusiform or
beaded rod )

 macrophages
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
OAT CELL  men usually
CARCINOMA/SMALL effected
CELL CARCINOMA  99% in
smokers
 AZZOPARDI
EFFECT
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
SQUAMOUS CELL  Commonly
CARCINOMA associated with
Men, smoking
 Islands of large
polygonal
malignant cells
,contains
keratin and
inter cellular
bridges
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
PULMONARY  NSCLC
ADENOCARCINOMA  Most common
type of lung
cancer in
females and
non smokers
young
 Lepidic pattern
 Acinar pattern
 Papillary
pattern
 Micropapillary
pattern
 Solid pattern
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
BRONCHIAL  Trabeculae of
CHARCINOID mediun sised
polygonal cells
with
eosinophilic
cytoplasm
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
 PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
MALIGNANT  Pleural
MESOTHELIOMA mesothelioma

 Incidence high
in people with
heavy
exposure to
asbestos
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY
PRELIM LAB GEN. PATHOLOGY LUNG PATHOLOGY