Name. …………………………….student Code …………………… Group …………..

Quiz : evidence based practice Date 9 August 2023

case. 1. There were 2 patients with Non-Hodgins Lymphoma

Mr. Aek. 37 yr Male, single, tx with R-CHOP
Life year gain 20 year with utility score = 0.6
Direct medication cost = 300,000 / month
Transportation cost = 3,000 / month
Unemployed cost = 50,000 / month

Mr. Pay 47 yr Male, single, tx Copanlisib (Aliqopa) targets the PI3K-alpha

Life year gain 10 year with utility score = 0.9
Direct medication cost = 1,000,000 / month
Transportation cost = 5,000 / month
Unemployed cost = 3,000 / month

Question 1: calculation total cost per year of R-CHOP

Question 2: calculation total cost per year of Copanlisib

Question 3 : calculation QALYs of R-CHOP

Question 4 : calculation QALYs of Copanlisib

Question 5 : calculation CER / Life yr gain (cost effectiveness ratio of

Copanlisib vs R-CHOP

Question 6 : calculation ICER / QALYs ( incremental cost effectiveness

ratio of Copanlisib vs R-CHOP

Question 7 : calculation NMB of R-CHOP

Question 8 : calculation NMB of Copanlisib

Question 9 : plot item of Copanlisib and R-CHOP
(draw willingness to pay and scale by yourself )
ICER +

QALYs +