taininmelanom: Shatod focel nee Sbltz c0-41: 2

dtuse
laneyhe me
Malamoma
vls
enelase saeche nem ahu, bpecifiu musleeytoleahy
Mimenhn, maness speiihe Nen
ambiqe membame epithelial
&peifcty elan-A and tMB- thamsensie
MS
tache
Nete
melamin tthes
melaneytes
in
iye matad pest 2
dew,qowth, (MiTE) facten
abilty melamonma 70 i6i
maliana Melrsi
igmented melamoeyhe wls
nom- melanocytes
NK-|c3
(ab MART- I 3.
neqatine
n -lo3) -AA Melan
lemoa Desmolastic
magine ineatinq D
Sungea Mohs (ah-body
neqatie eeh iMa-us):
metstoh
ytoerata sentineS-lsDMAt
1
Neweid Molan
canbarel kinoethy
Red Fast (i)
coleu brown
feene-
th (i)
Pmoteolyhi eeER:
epitope inded epitope
ndued ensgne hetieve)
clane auto
bat waku
uced (heat
Pnineiple:
loDemat
g- ol Relevae
histoleisty' Tmmuno
 classste

HiniceoNIPMOSOme Maintainemes proesha (MeM3 MM 4)

icohubwe asvited pokeun2 (M Af ), versicer,
phohohistone H Dysplas he' naevi) ukerhial sdg
melhome
Heat h h þvt ein l0c (HSe tos) : T-.mlanoma.

Gueese ranapites GLwT-1: benign melao uyhe naewi, -melane

Parsaneshe maens- Melawma

Nuclein-b

Cox-2, pPART ’metastais

HSP- los. widestad mets &þu P
ehaso-hishone Hs (þHHa) mitohe iactiuy
CeACAM(Caaciembnyml anhigen cel adheie' eledr )
RUNX3

Basal Cel cauinona

neulamets

eutanes adreatumusio
Adnexa & hidemal Tuenus cutanns meta-vÙaeral odemecAi
Desmoklash
Tihoehiteliom Bec Sweas
eot)
Bas
0-34

S-\0

Geoep1s
 DEpIs mamay
xha'
k-MA, CE A ehamammaN

neanhànent (vls non neiomdocne CA Oerpeyn

cytokehns neuiema)
ainiehoes ome aintenane nelea þoteus,

dema Jatt
nhndibulal anea coiat Lanahams cels D40: hain plkda

ALobecia

Apotoke bdsal leratineytes: bss,

IHc cutanens ynnomas

4 Abslule Sezay cel count wvD cls nm

2

3 Deenstahen t 1- ceel elene mmaleela fuqheme 'methos

Proma utanees
 clhssale

Pmmay cutaneons B- cel lyhemes

Pnmayeutaneeus follide cente tymhome
2
Pima cutneoms maaine B-el

CO ao, eos, BcL-2 ),B G

MUM- tRe-4

Pimay

pyoaeie gamado ma, qramlotien tises

E. Schamberas Disease

3 fnga
4-Protooad: Paeum tis cami
Paihe: Leihamia.

ARleg Contact permhhs :5HT14 SHI24A

 Thenapeuthe Apblicathn
eelularetabalie pataway
Tasgets
2. Homen

Parain emb edded tsinei hoeacaa

celula
detaL.
3 Decalciked necme ateras
4.

6. electronr hics toby

7.